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Phase II Pragmatic Randomized Controlled Trial of Patient-Led Therapies (Mirror Therapy and Lower-Limb Exercises) During Inpatient Stroke Rehabilitation
Conclusions. Both patient-led mirror therapy and lower-limb exercises during inpatient stroke care are safe, feasible, and acceptable and warrant further investigation. Practice for 5 to 15 minutes for 7 days is a realistic prescription unless strategies to enhance adherence are included. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - September 23, 2015 Category: Neurology Authors: Tyson, S., Wilkinson, J., Thomas, N., Selles, R., McCabe, C., Tyrrell, P., Vail, A. Tags: Clinical Research Articles Source Type: research

Does Action Observation Training With Immediate Physical Practice Improve Hemiparetic Upper-Limb Function in Chronic Stroke?
Conclusions. This study provides preliminary evidence of the additive value of action observation plus physical practice over relaxation-sham plus physical practice. There appears to be capacity for further recovery of upper-limb function in chronic stroke that persists at least in the short term. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - September 23, 2015 Category: Neurology Authors: Sugg, K., Muller, S., Winstein, C., Hathorn, D., Dempsey, A. Tags: Clinical Research Articles Source Type: research

Muscle Fatigability During a Sustained Index Finger Abduction and Depression Scores Are Associated With Perceived Fatigue in Patients With Relapsing-Remitting Multiple Sclerosis
Conclusions. The found association accentuates the importance of including both physiological fatigability-related and psychological mood–related constructs in models to explain perceived fatigue in patients with MS. The model also directs future research toward applying effortful conditions and emphasizes the importance of assessing different constructs when evaluating rehabilitation strategies to reduce MS-related fatigue. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - August 24, 2015 Category: Neurology Authors: Wolkorte, R., Heersema, D. J., Zijdewind, I. Tags: Clinical Research Articles Source Type: research

Spatial and Temporal Control Contribute to Step Length Asymmetry During Split-Belt Adaptation and Hemiparetic Gait
Conclusions. Our results suggest that changes in where the feet are placed or changes in interlimb timing could be used as compensatory strategies to reduce overall SLA in stroke survivors. These results may allow clinicians and researchers to identify patient-specific gait abnormalities and personalize their therapeutic approaches accordingly. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - August 24, 2015 Category: Neurology Authors: Finley, J. M., Long, A., Bastian, A. J., Torres-Oviedo, G. Tags: Clinical Research Articles Source Type: research

A Randomized Controlled Trial to Reduce Falls in People With Parkinson's Disease
Conclusions. Rehabilitation combining falls prevention education with strength training or movement strategy training reduces the rate of falls in people with mild to moderately severe PD and is feasible. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - August 24, 2015 Category: Neurology Authors: Morris, M. E., Menz, H. B., McGinley, J. L., Watts, J. J., Huxham, F. E., Murphy, A. T., Danoudis, M. E., Iansek, R. Tags: Clinical Research Articles Source Type: research

Wrist Rehabilitation Assisted by an Electromyography-Driven Neuromuscular Electrical Stimulation Robot After Stroke
Conclusions. The NMES robot–assisted wrist training was more effective than the pure robot. The additional NMES application in the treatment could bring more improvements in the distal motor functions and faster rehabilitation progress. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - August 24, 2015 Category: Neurology Authors: Hu, X.-L., Tong, R. K.-y., Ho, N. S. K., Xue, J.-j., Rong, W., Li, L. S. W. Tags: Clinical Research Articles Source Type: research

Changes in Strength, Sensation, and Prehension in Acute Cervical Spinal Cord Injury: European Multicenter Responsiveness Study of the GRASSP
Conclusion. The GRASSP showed excellent responsiveness, detecting distinct changes in strength and prehension relating to the severity of cervical SCI. It detected clinically significant changes complimentary to the ISNCSCI and SCIM-SS assessments. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - August 24, 2015 Category: Neurology Authors: Velstra, I.-M., Curt, A., Frotzler, A., Abel, R., Kalsi-Ryan, S., Rietman, J. S., Bolliger, M. Tags: Clinical Research Articles Source Type: research

Anodal tDCS Combined With Radial Nerve Stimulation Promotes Hand Motor Recovery in the Acute Phase After Ischemic Stroke
Conclusion. These results show that early cortical neuromodulation with anodal tDCS combined with rPNS can promote motor hand recovery and that the benefit is still present 1 month after the stroke. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - August 24, 2015 Category: Neurology Authors: Sattler, V., Acket, B., Raposo, N., Albucher, J.-F., Thalamas, C., Loubinoux, I., Chollet, F., Simonetta-Moreau, M. Tags: Clinical Research Articles Source Type: research

Boosting Cognition With Music in Patients With Disorders of Consciousness
Conclusions. These findings demonstrate for the first time that music has a beneficial effect on cognitive processes of patients with disorders of consciousness. The autobiographical characteristics of music, that is, its emotional and personal relevance, probably increase arousal and/or awareness. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - August 24, 2015 Category: Neurology Authors: Castro, M., Tillmann, B., Luaute, J., Corneyllie, A., Dailler, F., Andre-Obadia, N., Perrin, F. Tags: Clinical Research Articles Source Type: research

Method to Reduce Muscle Fatigue During Transcutaneous Neuromuscular Electrical Stimulation in Major Knee and Ankle Muscle Groups
Conclusions. Our study has revealed improvements in fatigue tolerance during transcutaneous neuromuscular electrical stimulation using SDSS, a stimulation strategy that alternates activation of subcompartments of muscles. The SDSS protocol can provide greater stimulation times with less decrement in mechanical output compared with the conventional protocol. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - August 24, 2015 Category: Neurology Authors: Sayenko, D. G., Nguyen, R., Hirabayashi, T., Popovic, M. R., Masani, K. Tags: Clinical Research Articles Source Type: research

Spaced Noninvasive Brain Stimulation: Prospects for Inducing Long-Lasting Human Cortical Plasticity
Neuroplasticity is critical for learning, memory, and recovery of lost function following neurological damage. Noninvasive brain stimulation (NIBS) techniques can induce neuroplastic changes in the human cortex that are behaviorally relevant, raising the exciting possibility that these techniques might be therapeutically beneficial for neurorehabilitation following brain injury. However, the short duration and instability of induced effects currently limits their usefulness. To date, trials investigating the therapeutic value of neuroplasticity-inducing NIBS have used either single or multiple treatment sessions, typically...
Source: Neurorehabilitation and Neural Repair - August 24, 2015 Category: Neurology Authors: Goldsworthy, M. R., Pitcher, J. B., Ridding, M. C. Tags: Clinical Research Articles Source Type: research

A Randomized Controlled Trial of the Effect of Early Upper-Limb Training on Stroke Recovery and Brain Activation
Conclusion. Early, more-intensive, UL training was associated with greater changes in activation in putative motor (supplementary motor area and cerebellum) and attention (anterior cingulate) regions, providing support for the role of these regions and functions in early recovery poststroke. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - August 24, 2015 Category: Neurology Authors: Hubbard, I. J., Carey, L. M., Budd, T. W., Levi, C., McElduff, P., Hudson, S., Bateman, G., Parsons, M. W. Tags: Clinical Research Articles Source Type: research

Daily Electrical Muscle Stimulation Enhances Functional Recovery Following Nerve Transection and Repair in Rats
Conclusions. Our results demonstrated that EMS using a moderate stimulation paradigm immediately following nerve transection and repair enhances electrophysiological and behavioral recovery. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - July 21, 2015 Category: Neurology Authors: Willand, M. P., Chiang, C. D., Zhang, J. J., Kemp, S. W. P., Borschel, G. H., Gordon, T. Tags: Basic Research Articles Source Type: research

BDNF Induced by Treadmill Training Contributes to the Suppression of Spasticity and Allodynia After Spinal Cord Injury via Upregulation of KCC2
Conclusions. BDNF-mediated restoration of KCC2 expression underlies the suppression of spasticity and allodynia caused by rehabilitation. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - July 21, 2015 Category: Neurology Authors: Tashiro, S., Shinozaki, M., Mukaino, M., Renault-Mihara, F., Toyama, Y., Liu, M., Nakamura, M., Okano, H. Tags: Basic Research Articles Source Type: research

Strategy Training Shows Promise for Addressing Disability in the First 6 Months After Stroke
Conclusions. Strategy training shows promise for addressing disability in the first 6 months after stroke. Lessons from this pilot study may inform future clinical trials. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - July 21, 2015 Category: Neurology Authors: Skidmore, E. R., Dawson, D. R., Butters, M. A., Grattan, E. S., Juengst, S. B., Whyte, E. M., Begley, A., Holm, M. B., Becker, J. T. Tags: Clinical Research Articles Source Type: research