Neurorehabilitation and Neural Repair This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Subcortical Volume Loss in the Thalamus, Putamen, and Pallidum, Induced by Traumatic Brain Injury, Is Associated With Motor Performance Deficits
Conclusions. Our results reveal that GM atrophy is associated with motor impairments in TBI, providing new insights into the etiology of motor control impairments following brain trauma. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - July 10, 2016 Category: Neurology Authors: Gooijers, J., Chalavi, S., Beeckmans, K., Michiels, K., Lafosse, C., Sunaert, S., Swinnen, S. P. Tags: Clinical Research Articles Source Type: research

Prefrontal Cortex Activation While Walking Under Dual-Task Conditions in Stroke: A Multimodal Imaging Study
Conclusion. Our results provide novel evidence that enhanced brain activity changes relate to dual task motor decrements. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - June 2, 2016 Category: Neurology Authors: Al-Yahya, E., Johansen-Berg, H., Kischka, U., Zarei, M., Cockburn, J., Dawes, H. Tags: Clinical Research Articles Source Type: research

Long-term Effectiveness of Intensive Therapy in Chronic Stroke
Conclusions. Motor benefits from intensive therapy compared with usual care were observed at 12 and 36 weeks posttherapy; however, this difference was attenuated at 36 weeks. Subgroups analysis showed that younger age, and a shorter time since stroke were associated with greater immediate and long-term improvement of motor function. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - June 2, 2016 Category: Neurology Authors: Wu, X., Guarino, P., Lo, A. C., Peduzzi, P., Wininger, M. Tags: Clinical Research Articles Source Type: research

Enhanced Neurobehavioral Outcomes of Action Observation Prosthesis Training
Conclusions. These results indicate that the type of limb imitated influences neural and behavioral strategies for novel prosthetic device usage. This finding is important, as customary prosthetic rehabilitation with intact therapists involves mismatched limb imitation that may exacerbate challenges in adapting to new motor patterns demanded by prosthesis use. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - June 2, 2016 Category: Neurology Authors: Cusack, W. F., Thach, S., Patterson, R., Acker, D., Kistenberg, R. S., Wheaton, L. A. Tags: Clinical Research Articles Source Type: research

Influence of Spinal Cord Integrity on Gait Control in Human Spinal Cord Injury
Conclusions. In motor-incomplete SCI, distinct clusters of discretely controlled gait parameters can be discerned that refine the evaluation of gait impairment beyond outcomes of walking speed and distance. These findings are specifically different from that in other neurological disorders (stroke, Parkinson) and are more discrete at targeting and disentangling the complex effects of interventions to improve walking outcome following motor-incomplete SCI. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - June 2, 2016 Category: Neurology Authors: Awai, L., Bolliger, M., Ferguson, A. R., Courtine, G., Curt, A. Tags: Clinical Research Articles Source Type: research

Short-Duration and Intensive Training Improves Long-Term Reaching Performance in Individuals With Chronic Stroke
In this study, we evaluated the long-term and generalization effects of short-duration and intensive reach training in 16 individuals with chronic stroke and mild to moderate impairments. Participants performed 2 sessions of unassisted intensive reach training, with 600 movements per session, and with display of performance-based feedback after each movement. The participants’ trunks were restrained with a belt to avoid compensatory movements. Training resulted in significant and durable (1 month) improvements in movement time (20.4% on average) and movement smoothness (22.7% on average). The largest improvements occ...
Source: Neurorehabilitation and Neural Repair - June 2, 2016 Category: Neurology Authors: Park, H., Kim, S., Winstein, C. J., Gordon, J., Schweighofer, N. Tags: Clinical Research Articles Source Type: research

An RCT to Treat Learning Impairment in Traumatic Brain Injury: The TBI-MEM Trial
Conclusion. The mSMT is effective for improving learning and memory in TBI. Classification of evidence. Based on widely accepted classification systems for treatment study design, this study provides class I evidence that the mSMT behavioral intervention improves both objective memory and everyday memory in persons with TBI over 5 weeks. Thus, this study extends the evidence for efficacy of the treatment protocol to a sample of persons with TBI. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - June 2, 2016 Category: Neurology Authors: Chiaravalloti, N. D., Sandry, J., Moore, N. B., DeLuca, J. Tags: Clinical Research Articles Source Type: research

Responsiveness of the Neuromuscular Recovery Scale During Outpatient Activity-Dependent Rehabilitation for Spinal Cord Injury
Conclusions. The NRS is a responsive measure that detects change in motor function during outpatient neurorehabilitation for SCI. There is potential utility for its application in randomized controlled trials and as a measure of clinical recovery across diverse SCI populations. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - June 2, 2016 Category: Neurology Authors: Tester, N. J., Lorenz, D. J., Suter, S. P., Buehner, J. J., Falanga, D., Watson, E., Velozo, C. A., Behrman, A. L., Michele Basso, D. Tags: Clinical Research Articles Source Type: research

Effects of Exercise on Falls, Balance, and Gait Ability in Parkinsons Disease: A Meta-analysis
The objectives of our study were to determine the effects of exercise training on the enhancement of balance and gait ability and reduction in falls for people with PD and to investigate potential factors contributing to the training effects on balance and gait ability of people with PD. We included 25 randomized control trials of a moderate methodological quality in our meta-analysis. The trials examined the effects of exercise training on balance and gait ability and falls against no intervention and placebo intervention. The results showed positive effects of exercise intervention on enhancing balance and gait performan...
Source: Neurorehabilitation and Neural Repair - June 2, 2016 Category: Neurology Authors: Shen, X., Wong-Yu, I. S. K., Mak, M. K. Y. Tags: Reviews Source Type: research

Exercise Training and Cognitive Rehabilitation: A Symbiotic Approach for Rehabilitating Walking and Cognitive Functions in Multiple Sclerosis?
The current review develops a rationale and framework for examining the independent and combined effects of exercise training and cognitive rehabilitation on walking and cognitive functions in persons with multiple sclerosis (MS). To do so, we first review evidence for improvements in walking and cognitive outcomes with exercise training and cognitive rehabilitation in MS. We then review evidence regarding cognitive–motor coupling and possible cross-modality transfer effects of exercise training and cognitive rehabilitation. We lastly present a macro-level framework for considering mechanisms that might explain impro...
Source: Neurorehabilitation and Neural Repair - June 2, 2016 Category: Neurology Authors: Motl, R. W., Sandroff, B. M., DeLuca, J. Tags: Reviews Source Type: research

Electrical Stimulation to Promote Peripheral Nerve Regeneration
This article aims to review the currently known biological basis for the regenerative effects of acute brief low-frequency electrical stimulation on axonal regeneration and outline the recent clinical applications of the electrical stimulation protocol to demonstrate the significant translational potential of this modality for repairing peripheral nerve injuries. The review concludes with a discussion of emerging new advancements in this exciting area of research. The current literature indicates the imminent clinical applicability of acute brief low-frequency electrical stimulation after surgical repair to effectively pro...
Source: Neurorehabilitation and Neural Repair - May 4, 2016 Category: Neurology Authors: Willand, M. P., Nguyen, M.-A., Borschel, G. H., Gordon, T. Tags: Basic Research Articles Source Type: research

Interactive Effects Between Exercise and Serotonergic Pharmacotherapy on Cortical Reorganization After Spinal Cord Injury
Conclusions. These results uncover the interactive effects between active/passive exercise and serotonergic pharmacotherapy on cortical reorganization after spinal cord injury, emphasizing the importance of understanding the effects of therapeutic strategies in spinal cord injury (and in other forms of deafferentation) from an integrated system-level approach. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - May 4, 2016 Category: Neurology Authors: Foffani, G., Shumsky, J., Knudsen, E. B., Ganzer, P. D., Moxon, K. A. Tags: Basic Research Articles Source Type: research

The Specific Requirements of Neural Repair Trials for Stroke
Novel molecular, cellular, and pharmacological therapies to stimulate repair of sensorimotor circuits after stroke are entering clinical trials. Compared with acute neuroprotection and thrombolysis studies, clinical trials for repair in subacute and chronic hemiplegic participants have a different time course for delivery of an intervention, different mechanisms of action within the milieu of the injury, distinct relationships to the amount of physical activity and skills practice of participants, and need to include more refined outcome measures. This review examines the biological interaction of targeted rehabilitation w...
Source: Neurorehabilitation and Neural Repair - May 4, 2016 Category: Neurology Authors: Dobkin, B. H., Carmichael, S. T. Tags: Clinical Research Articles Source Type: research

Is Period3 Genotype Associated With Sleep and Recovery in Patients With Disorders of Consciousness?
Conclusion. For the first time we have shown a possible association between Per3 polymorphism and consciousness recovery level in DOC patients. Even though the exact molecular mechanism has not been defined, we speculate that its effect is mediated by higher total sleep time and slow wave sleep, which would improve the preservation of main cerebral connections. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - May 4, 2016 Category: Neurology Authors: Bedini, G., Bersano, A., Sebastiano, D. R., Sattin, D., Ciaraffa, F., Tosetti, V., Brenna, G., Franceschetti, S., Ciusani, E., Leonardi, M., Vela-Gomez, J., Boncoraglio, G. B., Parati, E. A. Tags: Clinical Research Articles Source Type: research

Spatial Neglect Hinders Success of Inpatient Rehabilitation in Individuals With Traumatic Brain Injury: A Retrospective Study
Conclusions. Spatial neglect is common following TBI, impedes rehabilitation progress in both motor and cognitive domains, and prolongs length of stay. Future research is needed for linking specific traumatic injuries and lesioned networks to spatial neglect and related impairment. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - May 4, 2016 Category: Neurology Authors: Chen, P., Ward, I., Khan, U., Liu, Y., Hreha, K. Tags: Clinical Research Articles Source Type: research