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Virtual Reality-Based Training to Improve Obstacle-Crossing Performance and Dynamic Balance in Patients With Parkinson's Disease
Conclusions. VRWii training significantly improved obstacle crossing performance and dynamic balance, supporting implementation of VRWii training in participants with PD. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - July 21, 2015 Category: Neurology Authors: Liao, Y.-Y., Yang, Y.-R., Cheng, S.-J., Wu, Y.-R., Fuh, J.-L., Wang, R.-Y. Tags: Clinical Research Articles Source Type: research

Hand and Arm Bimanual Intensive Therapy Including Lower Extremity (HABIT-ILE) in Children With Unilateral Spastic Cerebral Palsy: A Randomized Trial
Conclusion. The findings suggest that combined upper and lower extremity in an intensive training protocol may be efficacious for improving both upper and lower extremity function in children with USCP. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - July 21, 2015 Category: Neurology Authors: Bleyenheuft, Y., Arnould, C., Brandao, M. B., Bleyenheuft, C., Gordon, A. M. Tags: Clinical Research Articles Source Type: research

Efficacy and Feasibility of Functional Upper Extremity Task-Specific Training for Older Adults With and Without Cognitive Impairment
Conclusions. Task-specific training may be appropriate for improving upper extremity function in older adults, yet future work in older patients with specific neurological conditions is needed. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - July 21, 2015 Category: Neurology Authors: Schaefer, S. Y., Dibble, L. E., Duff, K. Tags: Clinical Research Articles Source Type: research

Effects of Community Exercise Therapy on Metabolic, Brain, Physical, and Cognitive Function Following Stroke: A Randomized Controlled Pilot Trial
Conclusion. Exercise therapy improves short-term metabolic, brain, physical, and cognitive function, without changes in glucose control following stroke. The long-term impact of exercise on stroke recurrence, cardiovascular health, and disability should now be explored. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - July 21, 2015 Category: Neurology Authors: Moore, S. A., Hallsworth, K., Jakovljevic, D. G., Blamire, A. M., He, J., Ford, G. A., Rochester, L., Trenell, M. I. Tags: Clinical Research Articles Source Type: research

Generalizability of the Proportional Recovery Model for the Upper Extremity After an Ischemic Stroke
Conclusions. These results confirm in an independent sample that stroke patients with mild to moderate initial impairments show an almost fixed proportional upper extremity motor recovery. Patients who will most likely not achieve the predicted amount of recovery were identified using clinical determinants measured within 72 hours poststroke. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - July 21, 2015 Category: Neurology Authors: Winters, C., van Wegen, E. E. H., Daffertshofer, A., Kwakkel, G. Tags: Clinical Research Articles Source Type: research

A Single Session of Repetitive Transcranial Magnetic Stimulation Over the Dorsolateral Prefrontal Cortex in Patients With Unresponsive Wakefulness Syndrome: Preliminary Results
Conclusions. We demonstrated that a single session of 10-Hz rTMS over the right DLPFC may transiently improve consciousness and partially restore the connectivity within several cortical areas in some patients with UWS. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - July 21, 2015 Category: Neurology Authors: Naro, A., Russo, M., Leo, A., Bramanti, P., Quartarone, A., Calabro, R. S. Tags: Clinical Research Articles Source Type: research

Abu Dhabi Neuro Rehabilitation Conference 2015 Meeting Abstracts
(Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - July 21, 2015 Category: Neurology Tags: Meeting Abstracts Source Type: research

Training Intensity Affects Motor Rehabilitation Efficacy Following Unilateral Ischemic Insult of the Sensorimotor Cortex in C57BL/6 Mice
Discussion. These data indicate that increased training intensity increases the rate of functional improvements per time and per training session following ischemic insult. Thus, training intensity is an important variable to consider in efforts to optimize rehabilitation efficacy. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - June 25, 2015 Category: Neurology Authors: Bell, J. A., Wolke, M. L., Ortez, R. C., Jones, T. A., Kerr, A. L. Tags: Basic Research Articles Source Type: research

Effects of Physical Exercise on Neuroinflammation, Neuroplasticity, Neurodegeneration, and Behavior: What We Can Learn From Animal Models in Clinical Settings
Physical exercise is a cornerstone in the management of many neurodegenerative disorders, such as Parkinson’s disease, dementia, and stroke. However, much of its beneficial effects on improving motor functions and cognition as well as decreasing neurodegeneration and neuroinflammation are not yet well understood. The obvious limitations of studying the protective mechanisms behind exercise, for example, brain plasticity and neurodegeneration, could be overcome by generating novel animal models of neurodegenerative disorders. In this narrative review, we discuss the beneficial effects of exercise performed in animal m...
Source: Neurorehabilitation and Neural Repair - June 25, 2015 Category: Neurology Authors: Svensson, M., Lexell, J., Deierborg, T. Tags: Basic Research Articles Source Type: research

Interventions to Reduce Spasticity and Improve Function in People With Chronic Incomplete Spinal Cord Injury: Distinctions Revealed by Different Analytical Methods
Conclusions. Improvements in function were achieved in a limited number of people with SCI. Using the MID and GMM techniques, differences in responses to interventions between high-and low-functioning participants could be identified. These techniques may, therefore, have potential to be used for characterizing therapeutic effects resulting from different interventions. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - June 25, 2015 Category: Neurology Authors: Duffell, L. D., Brown, G. L., Mirbagheri, M. M. Tags: Clinical Research Articles Source Type: research

Impaired Functional Connectivity Unmasked by Simple Repetitive Motor Task in Early Relapsing-Remitting Multiple Sclerosis
Conclusions. Our study unmasked RS-FC changes of motor-related networks occurring after a simple repetitive motor task in early RRMS patients only. Evaluation of altered RSN dynamics might prove useful for anticipating neuroplasticity and for MRI-informed neurorehabilitation. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - June 25, 2015 Category: Neurology Authors: Petsas, N., Tomassini, V., Filippini, N., Sbardella, E., Tona, F., Piattella, M. C., Pozzilli, C., Wise, R. G., Pantano, P. Tags: Clinical Research Articles Source Type: research

Cortical Excitability During Passive Action Observation in Hospitalized Adults With Subacute Moderate to Severe Traumatic Brain Injury: A Preliminary TMS Study
Studies indicate that motor functions in patients with traumatic brain injury (TBI) can be improved with action observation. It has been hypothesized that this clinical practice relies on modulation of motor cortical excitability elicited by passive action observation in patients with TBI, a phenomenon shown thus far only in normal controls. The purpose of this work was to test this hypothesis and characterize the modulation of motor cortex excitability during passive action observation in patients with subacute moderate to severe TBI. We measured motor evoked potentials induced by single-pulse transcranial magnetic stimul...
Source: Neurorehabilitation and Neural Repair - June 25, 2015 Category: Neurology Authors: Fecteau, S., Dickler, M., Pelayo, R., Kumru, H., Bernabeu, M., Opisso Salleras, E., Tormos, J. M., Pascual-Leone, A. Tags: Clinical Research Articles Source Type: research

Placebo-Controlled Trial of Familiar Auditory Sensory Training for Acute Severe Traumatic Brain Injury: A Preliminary Report
Conclusions. For persons with DOC 29 to 170 days after TBI, FAST resulted in CNC gains and increased neural responsivity to vocal stimuli in language regions. Clinicians should consider providing the FAST to support patient engagement in neurorehabilitation. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - June 25, 2015 Category: Neurology Authors: Pape, T. L.-B., Rosenow, J. M., Steiner, M., Parrish, T., Guernon, A., Harton, B., Patil, V., Bhaumik, D. K., McNamee, S., Walker, M., Froehlich, K., Burress, C., Odle, C., Wang, X., Herrold, A. A., Zhao, W., Reda, D., Mallinson, T., Conneely, M., Nemeth, Tags: Clinical Research Articles Source Type: research

Combined Cognitive-Strategy and Task-Specific Training Improve Transfer to Untrained Activities in Subacute Stroke: An Exploratory Randomized Controlled Trial
Conclusion. CO-OP was associated with a large treatment effect on follow-up performances of self-selected activities and demonstrated transfer to untrained activities. A larger trial is warranted. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - June 25, 2015 Category: Neurology Authors: McEwen, S., Polatajko, H., Baum, C., Rios, J., Cirone, D., Doherty, M., Wolf, T. Tags: Clinical Research Articles Source Type: research

Efficacy of Constraint-Induced Movement Therapy in Early Stroke Rehabilitation: A Randomized Controlled Multisite Trial
Conclusions. Despite a favorable effect of CIMT on timed movement measures immediately after treatment, significant effects were not found after 6 months. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - June 25, 2015 Category: Neurology Authors: Thrane, G., Askim, T., Stock, R., Indredavik, B., Gjone, R., Erichsen, A., Anke, A. Tags: Clinical Research Articles Source Type: research