A Mirror Therapy-Based Action Observation Protocol to Improve Motor Learning After Stroke
Conclusion. The present study showed that a mirror therapy–based AO protocol contributes to motor learning after stroke. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - June 25, 2015 Category: Neurology Authors: Harmsen, W. J., Bussmann, J. B. J., Selles, R. W., Hurkmans, H. L. P., Ribbers, G. M. Tags: Clinical Research Articles Source Type: research

Paretic Propulsion and Trailing Limb Angle Are Key Determinants of Long-Distance Walking Function After Stroke
Conclusions. The paretic limb’s ability to generate propulsion during walking is a critical determinant of long-distance walking function after stroke. This finding supports the development of poststroke interventions that target deficits in propulsion and trailing limb angle. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - June 25, 2015 Category: Neurology Authors: Awad, L. N., Binder-Macleod, S. A., Pohlig, R. T., Reisman, D. S. Tags: Clinical Research Articles Source Type: research

Developing a Clinically Relevant Model of Cognitive Training After Experimental Traumatic Brain Injury
Conclusions. The results provide evidence that CCI-CogTrained rats that learned the nonspatial components of the MWM task applied these skills during multiple conditions of the place-learning task, thereby mitigating cognitive deficits typically associated with this injury model. The results show that a systematic application of clinically relevant constructs associated with cognitive training paradigms can be used with experimental TBI to affect place learning. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - May 28, 2015 Category: Neurology Authors: Brayer, S. W., Ketcham, S., Zou, H., Hurwitz, M., Henderson, C., Fuletra, J., Kumar, K., Skidmore, E., Thiels, E., Wagner, A. K. Tags: Basic Research Articles Source Type: research

Rehabilitative Training Promotes Rapid Motor Recovery but Delayed Motor Map Reorganization in a Rat Cortical Ischemic Infarct Model
Conclusions. Postinfarct rehabilitative training rapidly improves motor performance and movement quality after an ischemic infarct in motor cortex. However, training-induced motor improvements are not reflected in spared motor maps until substantially later, suggesting that early motor training after stroke can help shape the evolving poststroke neural network. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - May 28, 2015 Category: Neurology Authors: Nishibe, M., Urban, E. T. R., Barbay, S., Nudo, R. J. Tags: Basic Research Articles Source Type: research

Neural Point-and-Click Communication by a Person With Incomplete Locked-In Syndrome
This study demonstrates the first use of an intracortical brain–computer interface for neural point-and-click communication by an individual with incomplete locked-in syndrome. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - May 28, 2015 Category: Neurology Authors: Bacher, D., Jarosiewicz, B., Masse, N. Y., Stavisky, S. D., Simeral, J. D., Newell, K., Oakley, E. M., Cash, S. S., Friehs, G., Hochberg, L. R. Tags: Clinical Research Articles Source Type: research

A Low-Cost Cognitive Rehabilitation With a Commercial Video Game Improves Sustained Attention and Executive Functions in Multiple Sclerosis: A Pilot Study
Conclusion. We suggest that a home-based DKBT program may improve cognitive functions, some aspects of QoL, and cognitive fatigue in patients with MS. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - May 28, 2015 Category: Neurology Authors: De Giglio, L., De Luca, F., Prosperini, L., Borriello, G., Bianchi, V., Pantano, P., Pozzilli, C. Tags: Clinical Research Articles Source Type: research

Cortical Mechanisms of Mirror Therapy After Stroke
Conclusions. Mirror therapy could potentially aid stroke rehabilitation by normalizing an asymmetrical pattern of movement-related beta desynchronization in primary motor cortices during bilateral movement. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - May 28, 2015 Category: Neurology Authors: Rossiter, H. E., Borrelli, M. R., Borchert, R. J., Bradbury, D., Ward, N. S. Tags: Clinical Research Articles Source Type: research

Interrater Reliability of the Wolf Motor Function Test-Functional Ability Scale: Why It Matters
Conclusions and Implications. A systematic focus-group process was shown to be an effective method to improve reliability of observational assessment tools for motor behavior in neurorehabilitation. A reduction in noise-related variability in performance assessments will increase power and potentially lower the number needed to treat. Improved precision of measurement can lead to more cost-effective and efficient clinical trials. Finally, we suggest that improved precision in measures of motor behavior may provide more insight into recovery mechanisms than a single measure of movement time alone. (Source: Neurorehabilitati...
Source: Neurorehabilitation and Neural Repair - May 28, 2015 Category: Neurology Authors: Duff, S. V., He, J., Nelsen, M. A., Lane, C. J., Rowe, V. T., Wolf, S. L., Dromerick, A. W., Winstein, C. J. Tags: Clinical Research Articles Source Type: research

Reduced Dual-Task Performance in MS Patients Is Further Decreased by Muscle Fatigue
Conclusions. Compared with controls, MS patients performed less well on DTs as demonstrated by a reduction in both cognitive and motor performances. This performance decrease was stronger under fatiguing conditions and was related to the sense of fatigue of MS patients. These data illustrate problems that MS patients may encounter in daily life because of their fatigue. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - May 28, 2015 Category: Neurology Authors: Wolkorte, R., Heersema, D. J., Zijdewind, I. Tags: Clinical Research Articles Source Type: research

Walking Speed and Step Length Asymmetry Modify the Energy Cost of Walking After Stroke
Conclusions. For persons in the chronic phase of stroke recovery, faster and more symmetric walking after intervention appears to be more energetically advantageous than merely walking faster or more symmetrically. This finding has important functional implications, given the relationship between the energy cost of walking and community walking participation. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - May 28, 2015 Category: Neurology Authors: Awad, L. N., Palmer, J. A., Pohlig, R. T., Binder-Macleod, S. A., Reisman, D. S. Tags: Clinical Research Articles Source Type: research

SIRRACT: An International Randomized Clinical Trial of Activity Feedback During Inpatient Stroke Rehabilitation Enabled by Wireless Sensing
Conclusions. In this first trial of remote monitoring of inpatient stroke rehabilitation, augmented feedback beyond speed alone did not increase the time spent practicing or improve walking outcomes. Remarkably modest time was spent walking. Wireless sensing, however, allowed clinicians to audit skills practice and provided ground truth regarding changes in clinically important, mobility-related activities. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - May 28, 2015 Category: Neurology Authors: Dorsch, A. K., Thomas, S., Xu, X., Kaiser, W., Dobkin, B. H., on behalf of the SIRRACT investigators, Emara, Edwards, Fonzetti, Maasch, Lee, Owolabi, Hamzat, LeBlanc, Morse, Swaminathan, Karatas, Boza, Brown, Miyai, Kawano, Chen, Hanger, Zucconi, Mammi, G Tags: Clinical Research Articles Source Type: research

Machine-Based, Self-guided Home Therapy for Individuals With Severe Arm Impairment After Stroke: A Randomized Controlled Trial
This study compared self-guided, high-repetition home therapy with a mechanical device (the resonating arm exerciser [RAE]) to conventional therapy in patients with chronic stroke and explored RAE use for patients with subacute stroke. Methods. A total of 16 participants with severe upper-extremity impairment (mean Fugl-Meyer [FM] score = 21.4 ± 8.8 out of 66) >6 months poststroke were randomized to 3 weeks of exercise with the RAE or conventional exercises. The primary outcome measure was FM score 1 month posttherapy. Secondary outcome measures included Motor Activity Log, Visual Analog Pain Scale, and Ashworth ...
Source: Neurorehabilitation and Neural Repair - May 28, 2015 Category: Neurology Authors: Zondervan, D. K., Augsburger, R., Bodenhoefer, B., Friedman, N., Reinkensmeyer, D. J., Cramer, S. C. Tags: Clinical Research Articles Source Type: research

Quantitative Kinematic Characterization of Reaching Impairments in Mice After a Stroke
Conclusions. These results support the use of kinematic analysis in mice as a tool for both detection of poststroke functional impairments and tracking of motor improvements following rehabilitation. Similar studies could be performed in parallel with human studies to exploit the translational value of this skilled reaching analysis. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - March 25, 2015 Category: Neurology Authors: Lai, S., Panarese, A., Spalletti, C., Alia, C., Ghionzoli, A., Caleo, M., Micera, S. Tags: Clinical Research Articles Source Type: research

High-Frequency Transcutaneous Electrical Nerve Stimulation Alleviates Spasticity After Spinal Contusion by Inhibiting Activated Microglia in Rats
Conclusions. These results suggest that HF-TENS at 90% MT alleviates spasticity in rats with SCI by inhibiting activated microglia. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - March 25, 2015 Category: Neurology Authors: Hahm, S.-C., Yoon, Y. W., Kim, J. Tags: Clinical Research Articles Source Type: research

Electrical Stimulation of Abdominal Muscles to Produce Cough in Spinal Cord Injury: Effect of Stimulus Intensity
Conclusions. The plateau in expiratory cough flow that was associated with increasing expiratory pressures is indicative of dynamic airway compression. This suggests that the evoked cough will be effective in creating more turbulent airflow to further assist in dislodging mucus and secretions. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - March 25, 2015 Category: Neurology Authors: McBain, R. A., Boswell-Ruys, C. L., Lee, B. B., Gandevia, S. C., Butler, J. E. Tags: Clinical Research Articles Source Type: research