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Robotic Quantification of Position Sense in Children With Perinatal Stroke
Conclusions. Robotic assessment of position sense is feasible in children with perinatal stroke. Impairment is common and worse in arterial lesions. Limited correction with vision suggests cortical sensory network dysfunction. Disordered position sense may represent a therapeutic target in hemiparetic cerebral palsy. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - August 8, 2016 Category: Neurology Authors: Kuczynski, A. M., Dukelow, S. P., Semrau, J. A., Kirton, A. Tags: Clinical Research Articles Source Type: research

Effects of Pain and Pain Management on Motor Recovery of Spinal Cord-Injured Patients: A Longitudinal Study
Conclusion. While initial pain classification and intensity did not reveal an effect on motor recovery following acute SCI, anticonvulsants conferred a significant beneficial effect on motor outcomes. Early intervention with anticonvulsants may have effects beyond pain management and warrant further studies to evaluate the therapeutic effectiveness in human SCI. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - August 8, 2016 Category: Neurology Authors: Cragg, J. J., Haefeli, J., Jutzeler, C. R., Röhrich, F., Weidner, N., Saur, M., Maier, D. D., Kalke, Y. B., Schuld, C., Curt, A., Kramer, J. K. Tags: Clinical Research Articles Source Type: research

Contribution of Paretic and Nonparetic Limb Peak Propulsive Forces to Changes in Walking Speed in Individuals Poststroke
Conclusions. Gait retraining in the chronic phase of stroke recovery facilitates paretic limb neuromotor recovery and reduces the reliance on the nonparetic limb’s generation of propulsive force to increase walking speed. These findings support gait rehabilitation efforts directed toward improving the paretic limb’s ability to generate propulsive force. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - August 8, 2016 Category: Neurology Authors: Hsiao, H., Awad, L. N., Palmer, J. A., Higginson, J. S., Binder-Macleod, S. A. Tags: Clinical Research Articles Source Type: research

Somatosensory Impairments in the Upper Limb Poststroke: Distribution and Association With Motor Function and Visuospatial Neglect
Conclusions. Somatosensory impairments are common in subacute patients poststroke and are related to motor outcome. Visuospatial neglect was associated with more severe upper-limb somatosensory impairments. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - August 8, 2016 Category: Neurology Authors: Meyer, S., De Bruyn, N., Lafosse, C., Van Dijk, M., Michielsen, M., Thijs, L., Truyens, V., Oostra, K., Krumlinde-Sundholm, L., Peeters, A., Thijs, V., Feys, H., Verheyden, G. Tags: Clinical Research Articles Source Type: research

Postural Motor Learning Deficits in People With MS in Spatial but Not Temporal Control of Center of Mass
Conclusions: People with MS have the capacity to improve use of a feed-forward postural strategy with practice and retain the learned behavior for temporal not spatial control of CoM, despite their significant postural response impairments. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - August 8, 2016 Category: Neurology Authors: Gera, G., Fling, B. W., Van Ooteghem, K., Cameron, M., Frank, J. S., Horak, F. B. Tags: Clinical Research Articles Source Type: research

Sleep in the Acute Phase of Severe Traumatic Brain Injury: A Snapshot of Polysomnography
Conclusion. Patients in the acute stage of severe TBI exhibit increased sleep duration and earlier sleep onset, suggesting that the injured brain enhances sleep need and/or decreases the ability to maintain wakefulness. As poor sleep efficiency could compromise brain recovery, further studies should investigate whether strategies known to optimize sleep in healthy individuals are efficacious in acute TBI. While there are several inherent challenges, polysomnography is a useful means of examining sleep in the early stage of recovery in patients with severe TBI. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - August 8, 2016 Category: Neurology Authors: Wiseman-Hakes, C., Duclos, C., Blais, H., Dumont, M., Bernard, F., Desautels, A., Menon, D. K., Gilbert, D., Carrier, J., Gosselin, N. Tags: Clinical Research Articles Source Type: research

A Clinically Relevant Method of Analyzing Continuous Change in Robotic Upper Extremity Chronic Stroke Rehabilitation
Conclusions. The expanded analyses indicated that changes across time can occur in different ways but achieve similar goals and may be influenced by individual factors such as initial movement time. These findings will guide decisions regarding treatment planning based on rates of motor relearning during upper extremity stroke robotic interventions. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - August 8, 2016 Category: Neurology Authors: Massie, C. L., Du, Y., Conroy, S. S., Krebs, H. I., Wittenberg, G. F., Bever, C. T., Whitall, J. Tags: Clinical Research Articles Source Type: research

Delayed Exercise Is Ineffective at Reversing Aberrant Nociceptive Afferent Plasticity or Neuropathic Pain After Spinal Cord Injury in Rats
This study determined if delaying exercise intervention until pain is detected would similarly ameliorate established SCI-induced pain. Adult, female Sprague-Dawley rats with a C5 unilateral contusion were separated into SCI allodynic and SCI non-allodynic cohorts at 14 or 28 days postinjury when half of each group began exercising on automated running wheels. Allodynia, assessed by von Frey testing, was not ameliorated by exercise. Furthermore, rats that began exercise with no allodynia developed paw hypersensitivity within 2 weeks. At the initiation of exercise, the SCI Allodynia group displayed marked overlap of peptide...
Source: Neurorehabilitation and Neural Repair - July 10, 2016 Category: Neurology Authors: Detloff, M. R., Quiros-Molina, D., Javia, A. S., Daggubati, L., Nehlsen, A. D., Naqvi, A., Ninan, V., Vannix, K. N., McMullen, M.-K., Amin, S., Ganzer, P. D., Houle, J. D. Tags: Basic Research Articles Source Type: research

Vagus Nerve Stimulation During Rehabilitative Training Improves Forelimb Recovery After Chronic Ischemic Stroke in Rats
Conclusion. VNS paired with rehabilitative training confers significantly greater recovery of forelimb function after chronic ischemic stroke in rats. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - July 10, 2016 Category: Neurology Authors: Khodaparast, N., Kilgard, M. P., Casavant, R., Ruiz, A., Qureshi, I., Ganzer, P. D., Rennaker, R. L., Hays, S. A. Tags: Basic Research Articles Source Type: research

Improving Motor Corticothalamic Communication After Stroke Using Real-Time fMRI Connectivity-Based Neurofeedback
Conclusions. Our results document for the first time the feasibility and safety for patients with chronic stroke and severe motor impairment to self-regulate and augment ipsilesional cortico-subcortical connectivity through neurofeedback using real-time functional magnetic resonance imaging. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - July 10, 2016 Category: Neurology Authors: Liew, S.-L., Rana, M., Cornelsen, S., Fortunato de Barros Filho, M., Birbaumer, N., Sitaram, R., Cohen, L. G., Soekadar, S. R. Tags: Clinical Research Articles Source Type: research

Reducing The Cost of Transport and Increasing Walking Distance After Stroke: A Randomized Controlled Trial on Fast Locomotor Training Combined With Functional Electrical Stimulation
Conclusions. Combining fast locomotor training with FES is an effective approach to reducing the high EC of persons poststroke. Surprisingly, differences in 6MWT gains were not observed between groups. Closer inspection of the 6MWT and EC relationship and elucidation of how reduced EC may influence walking-related disability is warranted. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - July 10, 2016 Category: Neurology Authors: Awad, L. N., Reisman, D. S., Pohlig, R. T., Binder-Macleod, S. A. Tags: Clinical Research Articles Source Type: research

Imaging Predictors of Improvement From a Motor Learning-Based Intervention for Children With Unilateral Cerebral Palsy
Conclusions. Children with greater structural, functional and connective brain damage showed enhanced responses to bimanual intervention. Baseline imaging may identify parameters predicting response to intervention in children with UCP. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - July 10, 2016 Category: Neurology Authors: Schertz, M., Shiran, S. I., Myers, V., Weinstein, M., Fattal-Valevski, A., Artzi, M., Ben Bashat, D., Gordon, A. M., Green, D. Tags: Clinical Research Articles Source Type: research

Compensatory Versus Noncompensatory Shoulder Movements Used for Reaching in Stroke
Conclusions. The upper-limb flexor synergy was used adaptively for reaching accuracy by patients with mild, but not moderate/severe stroke. The flexor synergy, as parameterized by the amount of arm-plane motion, can be used by clinicians to identify levels of motor recovery in patients with stroke. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - July 10, 2016 Category: Neurology Authors: Levin, M. F., Liebermann, D. G., Parmet, Y., Berman, S. Tags: Clinical Research Articles Source Type: research

Does Poststroke Lower-Limb Spasticity Influence the Recovery of Standing Balance Control? A 2-Year Multilevel Growth Model
Conclusions. The present results suggest that the reduction in spasticity may be beneficial to balance control recovery. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - July 10, 2016 Category: Neurology Authors: Singer, J. C., Nishihara, K., Mochizuki, G. Tags: Clinical Research Articles Source Type: research

The Effects of Stroke Type, Locus, and Extent on Long-Term Outcome of Gait Rehabilitation: The LEAPS Experience
Conclusions. Type, locus, and extent of lesion, and the loss of substrate for neuroplastic effect as a result of prior stroke may affect long-term outcome of rehabilitation of hemiparetic gait. (Source: Neurorehabilitation and Neural Repair)
Source: Neurorehabilitation and Neural Repair - July 10, 2016 Category: Neurology Authors: Nadeau, S. E., Dobkin, B., Wu, S. S., Pei, Q., Duncan, P. W., for the LEAPS Investigative Team Tags: Clinical Research Articles Source Type: research