A 53 ‐year‐old woman with Cushing's disease and a pituitary tumor
(Source: Neuropathology)
Source: Neuropathology - June 13, 2016 Category: Neurology Authors: Valeria Barresi, Simona Lionti, Erika Messina, Felice Esposito, Filippo Flavio Angileri, Salvatore Cannav ò Tags: Neuropathology Education Source Type: research
A rare differentiation pattern of a common tumor arising in the frontal lobe in an elderly woman
(Source: Neuropathology)
Source: Neuropathology - June 13, 2016 Category: Neurology Authors: Kirti Gupta, Navneet Singla Tags: Neuropathology Education Source Type: research
Signaling of ghrelin and its functional receptor, the growth hormone secretagogue receptor, promote tumor growth in glioblastomas
Ghrelin is a 28‐amino‐acid peptide that is the endogenous ligand for the pituitary growth hormone secretagogue receptor (GHS‐R). Ghrelin is mainly produced from the stomach, but it is also expressed by various other tissues, including the CNS under normal conditions. Physiologically, ghrelin regulates appetite, gut motility, and GH release from the anterior pituitary, as well as cardiovascular and immune systems. Recent studies also indicate that ghrelin and GHS‐R may play an important autocrine/paracrine role in neoplastic conditions. In order to clarify the role of ghrelin/GHS‐R in gliomas, the present study as...
Source: Neuropathology - June 13, 2016 Category: Neurology Authors: Yousuke Okada, Yasuo Sugita, Koichi Ohshima, Motohiro Morioka, Satoru Komaki, Junko Miyoshi, Hideyuki Abe Tags: Original Article Source Type: research
Adult‐onset atypical teratoid/rhabdoid tumor featuring long spindle cells with nuclear palisading and perivascular pseudorosettes
Atypical teratoid/rhabdoid tumors (AT/RTs) are rare malignant neoplasms of the CNS that preferentially affect young children. We herein report an adult case of AT/RT surviving for more than 5 years with the residual tumor. The patient, a 24‐year‐old man at onset, presented with a contrast‐enhancing mass lesion in the left occipital lobe, and underwent partial tumor resection. Histologically, the tumor was predominantly composed of long spindle cells exhibiting nuclear palisading and perivascular pseudorosettes, which appeared to mimic mesenchymal, ependymal and Schwann cell tumors. A small number of isolated rhabdoi...
Source: Neuropathology - June 13, 2016 Category: Neurology Authors: Hidehisa Horiguchi, Satoshi Nakata, Sumihito Nobusawa, Shinichi Uyama, Tadashi Miyamoto, Hiromi Ueta, Naomi Fujimoto, Hideaki Yokoo Tags: Case Report Source Type: research
Characteristics of ganglion cells in pituitary gangliocytomas
We describe the pathological findings in three cases of growth hormone‐producing adenomas, all sparsely granulated, showing the presence of a ganglion cell population admixed with an adenomatous component. A review of the literature is also provided. (Source: Neuropathology)
Source: Neuropathology - May 31, 2016 Category: Neurology Authors: Mariangela Novello, Marco Gessi, Francesco Doglietto, Carmelo Anile, Libero Lauriola, Antonella Coli Tags: Case Report Source Type: research
