Presenting Numeric Information with Percentages and Descriptive Risk Labels: A Randomized Trial
Conclusions. Providing numeric AE-likelihood information in a percentage format with risk labels is likely to increase risk comprehension and willingness to use a medication compared with other numeric formats. (Source: Medical Decision Making)
Source: Medical Decision Making - October 1, 2015 Category: Health Management Authors: Sinayev, A., Peters, E., Tusler, M., Fraenkel, L. Tags: Original Articles Source Type: research

Validation of a Short, 3-Item Version of the Subjective Numeracy Scale
Conclusion: The SNS-3 is sufficiently reliable and valid to be used as a measure of subjective numeracy. (Source: Medical Decision Making)
Source: Medical Decision Making - October 1, 2015 Category: Health Management Authors: McNaughton, C. D., Cavanaugh, K. L., Kripalani, S., Rothman, R. L., Wallston, K. A. Tags: Brief Report Source Type: research

Mapping Functions in Health-Related Quality of Life: Mapping from Two Cancer-Specific Health-Related Quality-of-Life Instruments to EQ-5D-3L
Conclusions. OLS and tobit mapping functions perform well for both instruments. Response mapping gives the best model predictions for QLQ-C30. The generalizability of the FACT-G mapping function is limited to populations in moderate to good health. (Source: Medical Decision Making)
Source: Medical Decision Making - September 16, 2015 Category: Health Management Authors: Young, T. A., Mukuria, C., Rowen, D., Brazier, J. E., Longworth, L. Tags: Original Articles Source Type: research

Mapping from the Parkinson's Disease Questionnaire PDQ-39 to the Generic EuroQol EQ-5D-3L: The Value of Mixture Models
Conclusions. Finite mixture models with only few components can approximate the distribution of EQ-5D-3L utilities well but did not demonstrate improvements in predictive accuracy compared with multinomial logistic regression in the present data set. (Source: Medical Decision Making)
Source: Medical Decision Making - September 16, 2015 Category: Health Management Authors: Kent, S., Gray, A., Schlackow, I., Jenkinson, C., McIntosh, E. Tags: Original Articles Source Type: research

Predicting the EQ-5D-3L Preference Index from the SF-12 Health Survey in a National US Sample: A Finite Mixture Approach
Conclusions. Finite mixtures offer a flexible modeling approach that can take into account idiosyncratic characteristics of the distribution of preferences. The use of mixture models allows researchers to obtain estimates of health utilities when only summary scores from the SF-12 and a limited number of demographic characteristics are available. Mixture models are particularly useful when the target sample does not have a large proportion of individuals in good health. (Source: Medical Decision Making)
Source: Medical Decision Making - September 16, 2015 Category: Health Management Authors: Coca Perraillon, M., Shih, Y.-C. T., Thisted, R. A. Tags: Original Articles Source Type: research

Incorporating Psychological Predictors of Treatment Response into Health Economic Simulation Models: A Case Study in Type 1 Diabetes
Conclusions. By collecting data on psychological variables before an intervention, we can construct predictive models of treatment response to interventions. These predictive models can be incorporated into health economic models to investigate more complex service delivery and reimbursement strategies. (Source: Medical Decision Making)
Source: Medical Decision Making - September 16, 2015 Category: Health Management Authors: Kruger, J., Pollard, D., Basarir, H., Thokala, P., Cooke, D., Clark, M., Bond, R., Heller, S., Brennan, A. Tags: Original Articles Source Type: research

Applying Multiple Criteria Decision Analysis to Comparative Benefit-Risk Assessment: Choosing among Statins in Primary Prevention
Decision makers in different health care settings need to weigh the benefits and harms of alternative treatment strategies. Such health care decisions include marketing authorization by regulatory agencies, practice guideline formulation by clinical groups, and treatment selection by prescribers and patients in clinical practice. Multiple criteria decision analysis (MCDA) is a family of formal methods that help make explicit the tradeoffs that decision makers accept between the benefit and risk outcomes of different treatment options. Despite the recent interest in MCDA, certain methodological aspects are poorly understood...
Source: Medical Decision Making - September 16, 2015 Category: Health Management Authors: Tervonen, T., Naci, H., van Valkenhoef, G., Ades, A. E., Angelis, A., Hillege, H. L., Postmus, D. Tags: Original Articles Source Type: research

Understanding the Harms and Benefits of Cancer Screening: A Model of Factors That Shape Informed Decision Making
Conclusions. Even when information is counterintuitive and requires the integration of complex harms and benefits, user-friendly risk communications can facilitate comprehension, improve high-stakes decisions, and promote shared decision making. However, previous beliefs about the effectiveness of screening or strong fears about specific cancers may interfere with comprehension and informed decision making. (Source: Medical Decision Making)
Source: Medical Decision Making - September 16, 2015 Category: Health Management Authors: Petrova, D., Garcia-Retamero, R., Cokely, E. T. Tags: Original Articles Source Type: research

Evaluating Cost-effectiveness of Interventions That Affect Fertility and Childbearing: How Health Effects Are Measured Matters
Conclusions. Economic evaluations inconsistently consider QALYs from current and future fertility and childbearing in ways that frequently appear biased toward the interventions considered. As the Panel on Cost-Effectiveness in Health and Medicine updates its guidelines, making the practice of cost-effectiveness analysis more consistent is a priority. Our study contributes to harmonizing methods in this respect. (Source: Medical Decision Making)
Source: Medical Decision Making - September 16, 2015 Category: Health Management Authors: Goldhaber-Fiebert, J. D., Brandeau, M. L. Tags: Review Source Type: research

What Is Insufficient about Validation?
(Source: Medical Decision Making)
Source: Medical Decision Making - September 16, 2015 Category: Health Management Authors: Caro, J. J. Tags: Letters to the Editor Source Type: research

Validation Is Necessary but Insufficient
(Source: Medical Decision Making)
Source: Medical Decision Making - September 16, 2015 Category: Health Management Authors: Braithwaite, R. S., Roberts, M. S. Tags: Letters to the Editor Source Type: research

How Should We Estimate the Cost-effectiveness of Interventions That Affect Reproduction?
(Source: Medical Decision Making)
Source: Medical Decision Making - September 16, 2015 Category: Health Management Authors: Myers, E. R. Tags: Editorial Source Type: research

Stories of MDM: Helping Patients and Clinicians Manage Uncertainty during Clinical Care
(Source: Medical Decision Making)
Source: Medical Decision Making - September 16, 2015 Category: Health Management Authors: Politi, M. C. Tags: Web-Only Essay Source Type: research

Improving Geographic Equity in Kidney Transplantation Using Alternative Kidney Sharing and Optimization Modeling
The national demand for kidney transplantation far outweighs the supply of kidney organs. Currently, a patient's ability to receive a kidney transplant varies depending on where he or she seeks transplantation. This reality is in direct conflict with a federal mandate from the Department of Health and Human Services. We analyze current kidney allocation and develop an alternative kidney sharing strategy using a multiperiod linear optimization model, KSHARE. KSHARE aims to improve geographic equity in kidney transplantation while also respecting transplant system constraints and priorities. KSHARE is tested against actual 2...
Source: Medical Decision Making - August 1, 2015 Category: Health Management Authors: Davis, A. E., Mehrotra, S., Friedewald, J. J., Daskin, M. S., Skaro, A. I., Abecassis, M. M., Ladner, D. P. Tags: Original Articles Source Type: research

Predicting Liver Transplant Capacity Using Discrete Event Simulation
The number of liver transplants (LTs) performed in the US increased until 2006 but has since declined despite an ongoing increase in demand. This decline may be due in part to decreased donor liver quality and increasing discard of poor-quality livers. We constructed a discrete event simulation (DES) model informed by current donor characteristics to predict future LT trends through the year 2030. The data source for our model is the United Network for Organ Sharing database, which contains patient-level information on all organ transplants performed in the US. Previous analysis showed that liver discard is increasing and ...
Source: Medical Decision Making - August 1, 2015 Category: Health Management Authors: Toro-Diaz, H., Mayorga, M. E., Barritt, A. S., Orman, E. S., Wheeler, S. B. Tags: Original Articles Source Type: research