Testicular adrenal rest tumor in 11-Beta-hydroxylase deficiency driven congenital adrenal hyperplasia.
Authors: Kaynar M, Sönmez MG, Unlü Y, Karatağ T, Tekinarslan E, Sümer A Abstract Testicular adrenal rest tumors (TART) occur often as asymptomatic nodules in corticotropin-dependent lesions aberrant adrenal tissue in congenital adrenal hyperplasia (CAH) patients. The present manuscript is about an unusual case of a 16-year-old CAH patient due to 11β-hydroxylase deficiency. He underwent testicle biopsy because of testicle tumor suspicion and diagnosed with TART. PMID: 24741421 [PubMed] (Source: Korean Journal of Urology)
Source: Korean Journal of Urology - December 1, 2014 Category: Urology & Nephrology Tags: Korean J Urol Source Type: research

Penile low-intensity shock wave therapy: a promising novel modality for erectile dysfunction.
Authors: Abu-Ghanem Y, Kitrey ND, Gruenwald I, Appel B, Vardi Y Abstract Penile extracorporeal low-intensity shock wave therapy (LIST) to the penis has recently emerged as a novel and promising modality in the treatment of erectile dysfunction (ED). LIST has angiogenic properties and stimulates neovascularization. If applied to the corpora cavernosa, LIST can improve penile blood flow and endothelial function. In a series of clinical trials, including randomized double-blind sham-controlled studies, LIST has been shown to have a substantial effect on penile hemodynamics and erectile function in patients wi...
Source: Korean Journal of Urology - December 1, 2014 Category: Urology & Nephrology Tags: Korean J Urol Source Type: research

Epidemiology of lower urinary tract symptoms: emphasis on the status in Korea.
Authors: Lee H, Jeong SJ Abstract A comprehensive and correct understanding of epidemiologic finding about lower urinary tract symptoms (LUTS) is important for several reasons. First, LUTS are highly prevalent in both genders all around the world and are expected to be a major concern to physicians in the near future because of the rapid rise in the elderly population. Second, it is crucial to observe trends in prevalence when national health care policy is established. By using a Medline search with various terms related to LUTS and prevalence, a review of epidemiologic studies was undertaken with an emph...
Source: Korean Journal of Urology - December 1, 2014 Category: Urology & Nephrology Tags: Korean J Urol Source Type: research

Pulmonary metastases after low-dose-rate brachytherapy for localized prostate cancer.
CONCLUSIONS: LDR-BT for biologically aggressive PCa may be linked to possible pulmonary metastasis owing to tumor dissemination during seed implantation. This information is important in planning adequate treatment for these patients. PMID: 24868334 [PubMed] (Source: Korean Journal of Urology)
Source: Korean Journal of Urology - December 1, 2014 Category: Urology & Nephrology Tags: Korean J Urol Source Type: research

Efficacy of Bicalutamide 150-mg Monotherapy Compared With Combined Androgen Blockade in Patients With Locally Advanced Prostate Cancer.
CONCLUSIONS: The PSA change, mean survival rate, and adverse events in patients with locally advanced prostate cancer treated with bicalutamide 150-mg and CAB did not differ significantly. However, sexual function was better in the bicalutamide 150-mg group. Therefore, bicalutamide 150-mg monotherapy could be considered as a treatment for locally advanced prostate cancer in patients concerned about sexual function. PMID: 24868335 [PubMed] (Source: Korean Journal of Urology)
Source: Korean Journal of Urology - December 1, 2014 Category: Urology & Nephrology Tags: Korean J Urol Source Type: research

Predictive value of the cancer of the prostate risk assessment score for recurrence-free survival after radical prostatectomy in Korea: a single-surgeon series.
CONCLUSIONS: The CAPRA score showed high accuracy for predicting RFS. In particular, the three-group model was more useful for predicting RFS and pathologic outcomes. Therefore, the CAPRA score may be a useful prediction model for risk stratification and may help clinicians to develop localized prostate cancer treatment. PMID: 24868336 [PubMed] (Source: Korean Journal of Urology)
Source: Korean Journal of Urology - December 1, 2014 Category: Urology & Nephrology Tags: Korean J Urol Source Type: research

Prognosis of prostate cancer with other primary malignancies.
CONCLUSIONS: Prostate cancer prognosis after RP is not dependent on the presence or absence of other primary malignancies. However, other primary malignancies diagnosed after RP for prostate cancer negatively affect OS. PMID: 24868337 [PubMed] (Source: Korean Journal of Urology)
Source: Korean Journal of Urology - December 1, 2014 Category: Urology & Nephrology Tags: Korean J Urol Source Type: research

Efficacy and Safety of the Selective α1A-Adrenoceptor Blocker Silodosin for Severe Lower Urinary Tract Symptoms Associated With Benign Prostatic Hyperplasia: A Prospective, Single-Open-Label, Multicenter Study in Korea.
CONCLUSIONS: Silodosin 8 mg once daily may be effective and safe in Korean patients with severe LUTS associated with BPH. PMID: 24868338 [PubMed] (Source: Korean Journal of Urology)
Source: Korean Journal of Urology - December 1, 2014 Category: Urology & Nephrology Tags: Korean J Urol Source Type: research

Chronic lower urinary tract symptoms in young men without symptoms of chronic prostatitis: urodynamic analyses in 308 men aged 50 years or younger.
CONCLUSIONS: Because clinical symptoms are not useful for predicting the specific urodynamic etiology of LUTS in this population, urodynamic investigation can help to make an accurate diagnosis and, potentially, to guide appropriate treatment. PMID: 24868339 [PubMed] (Source: Korean Journal of Urology)
Source: Korean Journal of Urology - December 1, 2014 Category: Urology & Nephrology Tags: Korean J Urol Source Type: research

Unexpected Multidrug Resistance of Methicillin-Resistant Staphylococcus aureus in Urine Samples: A Single-Center Study.
CONCLUSIONS: MRSA showed a decreasing trend of antimicrobial resistance, except against carbapenem, cephalosporin (1st-4th generation), penicillin G, aminopenicillin, β-lactamase, and isoxazolyl penicillin, for which complete resistance was observed. PMID: 24868340 [PubMed] (Source: Korean Journal of Urology)
Source: Korean Journal of Urology - December 1, 2014 Category: Urology & Nephrology Tags: Korean J Urol Source Type: research

Instillation of Hyaluronic Acid via Electromotive Drug Administration Can Improve the Efficacy of Treatment in Patients With Interstitial Cystitis/Painful Bladder Syndrome: A Randomized Prospective Study.
CONCLUSIONS: Hyaluronic acid installation is an effective glycosaminoglycan substitution therapy in patients with BPS/IC. Instillation of hyaluronic acid via EMDA can improve the efficacy of the treatment; however, lack of long-term efficacy is the major problem with this glycosaminoglycan substitution therapy. PMID: 24868341 [PubMed] (Source: Korean Journal of Urology)
Source: Korean Journal of Urology - December 1, 2014 Category: Urology & Nephrology Tags: Korean J Urol Source Type: research

Misplacement or migration? Extremely rare case of cardiac migration of a ureteral j stent.
Authors: Kim TN, Lee CH, Kong do H, Shin DK, Lee JZ Abstract A 29-year-old woman with mild back pain when coughing and suprapubic discomfort after voiding was admitted to Pusan National University Hospital. Two weeks earlier, she had undergone a hysterectomy and right-sided ureteroneocystostomy for uterine atony and right ureteral injury with bladder rupture. Computed tomography showed that a ureteral J stent extended from the right ovarian vein to the right cardiac chamber. The stent was retrieved via both femoral veins with a snare loop and pigtail catheter. Computed tomography showed that the urinary an...
Source: Korean Journal of Urology - December 1, 2014 Category: Urology & Nephrology Tags: Korean J Urol Source Type: research

Large bilateral adrenal leiomyomas presenting as calcified adrenal masses: a rare case report.
We report the case of a 55-year-old woman with bilateral, large, calcified adrenal tumors who was treated by laparoscopic adrenalectomy. The patient presented with upper abdominal discomfort for the past 5 years. Her imaging showed bilateral enlarged adrenal glands up to 10-cm size with punctate calcifications. Positron emission tomography scan demonstrated moderate fluorodeoxyglucose avidity in the left adrenal mass. Bilateral laparoscopic adrenalectomy was performed through a transperitoneal approach. The postoperative period was uneventful, and the patient was discharged on the third postoperative day. Histology finding...
Source: Korean Journal of Urology - December 1, 2014 Category: Urology & Nephrology Tags: Korean J Urol Source Type: research

The dark side of 5α-reductase inhibitors' therapy: sexual dysfunction, high Gleason grade prostate cancer and depression.
Authors: Traish AM, Mulgaonkar A, Giordano N Abstract With aging, abnormal benign growth of the prostate results in benign prostate hyperplasia (BPH) with concomitant lower urinary tract symptoms (LUTS). Because the prostate is an androgen target tissue, and transforms testosterone into 5α-dihydrotestosterone (5α-DHT), a potent androgen, via 5α-reductase (5α-R) activity, inhibiting this key metabolic reaction was identified as a target for drug development to treat symptoms of BPH. Two drugs, namely finasteride and dutasteride were developed as specific 5α-reductase inhibitors (5α-RIs) and were appro...
Source: Korean Journal of Urology - December 1, 2014 Category: Urology & Nephrology Tags: Korean J Urol Source Type: research

Robot-assisted laparoendoscopic single-site partial nephrectomy with the novel da vinci single-site platform: initial experience.
CONCLUSIONS: Our initial experience with R-LESS PN with the novel Da Vinci platform shows that even though the procedure is feasible, it should be applied in only appropriately selected patients. However, further improvement is needed to overcome the existing limitations. PMID: 24955221 [PubMed] (Source: Korean Journal of Urology)
Source: Korean Journal of Urology - December 1, 2014 Category: Urology & Nephrology Tags: Korean J Urol Source Type: research