The significance of changes in pupil size during straylight measurement and with varying environmental illuminance
Conclusion We conclude that the illuminance of the examination room during straylight assessment does not affect the outcome in normal eyes. In fact, under mesopic and scotopic conditions, the luminance of the test field is so much higher than that of the room so that it determines the pupil size. Regardless of the lighting level, straylight measured in a laboratory, is valid for photopic pupils at an adaptation level corresponding with about 400 lux room illuminance. (Source: Journal of Optometry)
Source: Journal of Optometry - November 12, 2017 Category: Opthalmology Source Type: research

Beta2 adrenergic receptor silencing change intraocular pressure in New Zealand rabbits
Conclusion The use of siRNA against the beta2 adrenergic receptors could provide an interesting therapeutic strategy for glaucoma treatment. (Source: Journal of Optometry)
Source: Journal of Optometry - November 11, 2017 Category: Opthalmology Source Type: research

Comparison of cyclopentolate versus tropicamide cycloplegia: A systematic review and meta-analysis
Conclusion We suggest that tropicamide may be considered as a viable substitute for cyclopentolate due to its rapid onset of action. Although these results should be used cautiously in infants and in patients with high hyperopia or strabismus when using tropicamide as the sole cycloplegic agent especially in situations that the findings are variable or there is no consistency between the examination results and clinical manifestations of the visual problems. (Source: Journal of Optometry)
Source: Journal of Optometry - November 11, 2017 Category: Opthalmology Source Type: research

Science, pseudoscience, evidence-based practice and post truth
Publication date: October–December 2017 Source:Journal of Optometry, Volume 10, Issue 4 Author(s): José M. González-Méijome (Source: Journal of Optometry)
Source: Journal of Optometry - September 11, 2017 Category: Opthalmology Source Type: research

Comparison of manual & amp; automated analysis methods for corneal endothelial cell density measurements by specular microscopy
Conclusion Our findings show that automated analysis significantly overestimates ECD in the eyes with high polymegathism and/or large cell size, compared to the manual method. Therefore, we discourage reliance upon the fully-automated method alone to perform specular microscopy analysis, particularly if an accurate ECD value is imperative. (Source: Journal of Optometry)
Source: Journal of Optometry - August 8, 2017 Category: Opthalmology Source Type: research

Agreement between total corneal astigmatism calculated by vector summation and total corneal astigmatism measured by ray tracing using Galilei double Scheimpflug analyzer
Conclusion The magnitudes and axes of astigmatisms measured by the vector summation and ray tracing methods cannot be used interchangeably. There was a systematic error between the TCAVec and TCARay magnitudes. (Source: Journal of Optometry)
Source: Journal of Optometry - August 4, 2017 Category: Opthalmology Source Type: research

Reactive oxygen species, oxidative stress, glaucoma and hyperbaric oxygen therapy
Publication date: Available online 29 July 2017 Source:Journal of Optometry Author(s): Charles McMonnies This review examines the role of oxidative stress in damage to cells of the trabecular meshwork and associated impaired aqueous drainage as well as damage to retinal ganglion cells and associated visual field losses. Consideration is given to the interaction between vascular and mechanical explanations for pathological changes in glaucoma. For example, elevated intraocular pressure (IOP) forces may contribute to ischaemia but there is increasing evidence that altered blood flow in a wider sense is also involved. Both...
Source: Journal of Optometry - July 29, 2017 Category: Opthalmology Source Type: research

More sensitive correlation of afferent pupillary defect with ganglion cell complex
Conclusions Significant correlations between RNFLT loss for cpRNFLT, pcpRNFLT and GCC parameters with RAPD were observed. Approximately a 35% higher sensitivity was obtained using GCC compared to CRNFL parameters. The expected change in GCC average for every 0.3log unit increment was approximately 8.49μm. The FLV% corresponded more sensitively to a RAPD but appeared to be influenced by disease severity. (Source: Journal of Optometry)
Source: Journal of Optometry - July 2, 2017 Category: Opthalmology Source Type: research

Assessment of neuro-optometric rehabilitation using the Developmental Eye Movement (DEM) test in adults with acquired brain injury
Discussion The results of the present study demonstrated considerable improvements in the DEM test scores following the oculomotor-based training, thus reflecting more time-optimal and accurate saccadic tracking after the training. The DEM test should be considered as another clinical test of global saccadic tracking performance in the ABI population. (Source: Journal of Optometry)
Source: Journal of Optometry - July 2, 2017 Category: Opthalmology Source Type: research

Binocular vision in the twenty-first century
Publication date: July–September 2017 Source:Journal of Optometry, Volume 10, Issue 3 Author(s): Kenneth J. Ciuffreda (Source: Journal of Optometry)
Source: Journal of Optometry - June 23, 2017 Category: Opthalmology Source Type: research

Relationship between vessel diameter and depth measurements within the limbus using ultra-high resolution optical coherence tomography
Conclusion This study demonstrated that the UHR-OCT was capable of imaging morphometric characteristics such as the size and depth of vessels in the limbus. The results of this study suggest a difference in the size and depth of vessels across different positions of the limbus, which may be indicative of adaptations to chronic hypoxia caused by the covering of the superior limbus by the upper eyelid. UHR-OCT may be a useful tool to evaluate the effect of contact lenses on the microvascular properties within the limbus. (Source: Journal of Optometry)
Source: Journal of Optometry - June 20, 2017 Category: Opthalmology Source Type: research

Extended depth of focus contact lenses vs. two commercial multifocals: Part 2. Visual performance after 1 week of lens wear
Conclusions EDOF provides better intermediate and near vision performance than either AOMF or AOP with no difference for distance vision after 1 week of lens wear. (Source: Journal of Optometry)
Source: Journal of Optometry - June 13, 2017 Category: Opthalmology Source Type: research

Extended depth of focus contact lenses vs. two commercial multifocals: Part 1. Optical performance evaluation via computed through-focus retinal image quality metrics
Conclusion With the through focus retinal image quality as the gauge of optical performance, we demonstrated that the prototype EDOF designs were less susceptible to variations in pupil, inherent ocular aberrations and decentration, compared to the commercial designs. To ascertain whether these incremental improvements translate to a clinically palpable outcome requires investigation through human trials. (Source: Journal of Optometry)
Source: Journal of Optometry - June 10, 2017 Category: Opthalmology Source Type: research

Orbital magnetic resonance imaging is useful in age-related distance esotropia
Conclusions MRI showed that displacements of LR and LR–SR band degeneration could facilitate the diagnosis of patients with ARDE. (Source: Journal of Optometry)
Source: Journal of Optometry - June 8, 2017 Category: Opthalmology Source Type: research

Refraction during incipient presbyopia: The Aston Longitudinal Assessment of Presbyopia (ALAP) study
Conclusion The incidence of a myopic shift in refraction during incipient presbyopia does not appear to be as large as previously indicated by retrospective research. The changes in axis indicate ocular astigmatism tends towards the against-the-rule direction with age. The structural origin(s) of the reported myopic shift in refraction during incipient presbyopia warrants further investigation. (Source: Journal of Optometry)
Source: Journal of Optometry - June 8, 2017 Category: Opthalmology Source Type: research