Comparison of manual & amp; automated analysis methods for corneal endothelial cell density measurements by specular microscopy

Conclusion Our findings show that automated analysis significantly overestimates ECD in the eyes with high polymegathism and/or large cell size, compared to the manual method. Therefore, we discourage reliance upon the fully-automated method alone to perform specular microscopy analysis, particularly if an accurate ECD value is imperative.

Source: Journal of Optometry - August 8, 2017 Category: Opthalmology Source Type: research