Localization and expression of CTP: Phosphocholine cytidylyltransferase in rat brain following cocaine exposure
Publication date: March 2019Source: Journal of Chemical Neuroanatomy, Volume 96Author(s): Sumitra Pati, Lishann M. Ingram, Min K. Sun, John J. Wagner, Brian S. CummingsAbstractPhosphatidylcholine (PC) is a primary phospholipid and major source of secondary lipid messengers and also serves as a biosynthetic precursor for other membrane phospholipids. Phosphocholine cytidylyltransferase (CCT) is the rate-limiting enzyme responsible for catalyzing the formation of PC. Changes in CCT activity have been associated with lipid dysregulation across various neurological disorders. Additionally, intermediates in PC synthesis, such a...
Source: Journal of Chemical Neuroanatomy - November 21, 2018 Category: Neuroscience Source Type: research
Increased cell number with reduced nitric oxide level and augmented superoxide dismutase activity in the anterior-pituitary region of young suicide completers
This study demonstrates that there is an increased number of cells, with an imbalance in oxidative stress without a process of lipid peroxidation in the anterior-pituitary region of young suicide completers.Graphical abstract (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - November 11, 2018 Category: Neuroscience Source Type: research
Neurochemical fingerprinting of amygdalostriatal and intra-amygdaloid projections: a tracing–immunofluorescence study in the rat
Publication date: Available online 6 November 2018Source: Journal of Chemical NeuroanatomyAuthor(s): Floris G. Wouterlood, Sanne van Oort, Lucian Bloemhard, Nico A. Flierman, Jorik Spijkerman, Chris I. Wright, Jeroen A.M. Beliën, Hendrik J. GroenewegenAbstractAmygdalostriatal and intra-amygdaloid fiber connectivity was studied in rats via injections of one of the tracers Phaseolus vulgaris leucoagglutinin (PHA-L) or biotinylated dextran amine (BDA) into various amygdaloid nuclei. To determine the neurotransmitter identity of labeled fibers we combined tracer detection with immunofluorescence staining, using antibodies aga...
Source: Journal of Chemical Neuroanatomy - November 7, 2018 Category: Neuroscience Source Type: research
Aromatase expression and function in the brain and behavior: A comparison across communication systems in teleosts
Publication date: December 2018Source: Journal of Chemical Neuroanatomy, Volume 94Author(s): Katherine ShawAbstractAromatase (Cyp19a1) is a steroidogenic enzyme that functions to convert aromatizable androgens into bioactive estrogens. The teleost brain is known to have the highest levels of aromatase activity among vertebrates, yet we know relatively little about the function of local estrogen production in teleost behavior. This review compares and contrasts the findings from behavioral studies in the visual, auditory, electrosensory, and olfactory systems, with expression studies in the brain and peripheral nervous syst...
Source: Journal of Chemical Neuroanatomy - November 7, 2018 Category: Neuroscience Source Type: research
Tooth pulp injury induces sex-dependent neuronal reshaping in the ventral posterolateral nucleus of the rat thalamus
Publication date: Available online 2 November 2018Source: Journal of Chemical NeuroanatomyAuthor(s): Ismael Juárez, Julio César Morales-Medina, Julia Flores-Tochihuitl, Gamaliel Santiago Juárez, Gonzalo Flores, Hortencia Chávez OsekiAbstractOrofacial injuries often result in persistent pain and are therefore considered a common health problem worldwide. Considerable evidence suggests that peripheral sensory nerve injury results in diverse plastic changes in the central nervous system (CNS). Tooth pulp is innervated by trigeminal afferents which extend to the trigeminal brainstem sensory nuclear complex and send input t...
Source: Journal of Chemical Neuroanatomy - November 3, 2018 Category: Neuroscience Source Type: research
