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Aggressive ameloblastic fibrosarcoma in maxilla: case report and new perspectives based on the current literature
ABSTRACT Ameloblastic fibrosarcoma (AFS) is a rare malignant tumor characterized by benign epithelial component within a malignant fibrous stroma. It occurs as a de novo lesion or from a previous ameloblastic fibroma. The aim of this paper is to report an aggressive and recurrent case of AFS in the maxilla of a 38-year-old patient. Histopathological diagnosis can be challenging, especially when it is based on incisional biopsy specimens. Hence, this report highlights not only the importance of the histological features for diagnosis but also the clinical behavior of AFS based on current literature evidence.RESUMO O fibross...
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - December 9, 2016 Category: Pathology Source Type: research

Angiosarcoma of small intestine: case report and literature review
Conclusion: This case demonstrates the difficulty in early diagnosing this pathology, due to its nonspecific clinical presentation. The disease aggressiveness, its unestablished predisposing factors and the controversy around the adequate treatment engender the poor prognosis.RESUMO Introdu ção: Angiossarcomas são patologias raras, e o aparecimento deles no intestino delgado é extremamente incomum. Relato de caso: Paciente do sexo feminino apresentando vômitos, cólica, distensão abdominal e irritação peritoneal. Foram realizadas laparotomia exploratória e enterectomia, evide nciando-se neoplasia vascular ao ana...
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - December 9, 2016 Category: Pathology Source Type: research

Preventable causes of death and factors associated with newborn survival at a university hospital in Curitiba, Paraná, Brazil
Conclusion: The incidence of preventable causes of death is probably lower when analyzed concurrently with the underlying disease. Cyanosis, gestational age, cause of death, Apgar< 6 and arterial blood pH are associated with survival time of newborns.RESUMO Introdu ção: A análise de óbitos ocorridos no período neonatal e a associação desses dados aos de necrópsias são fundamentais no auxílio à redução da taxa de mortalidade infantil no mundo. Objetivos: Observar as causas evitáveis de morte e os fatores associados ao maior risco de óbito neonat al precoce. Métodos: Foi realizado estudo transversal e d...
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - December 9, 2016 Category: Pathology Source Type: research

Protein molecular modeling of genetic markers for thyroid cancer
Conclusion: This study shows the importance of understanding the molecular structure of the markers for thyroid cancer through bioinformatics, and consequently, the development of more effective new molecules as alternative tools for thyroid cancer treatment.RESUMO Introdu ção: Os avanços nos estudos de biologia molecular da tireoide não fornecem apenas uma visão sobre as doenças tireoidianas, mas um diagnóstico preciso do câncer de tireoide. Objetivo: Realizar um tutorial sobre modelagem molecular proteica dos marcadores genéticos do câncer de tireoide. M étodos: As proteínas foram selecionadas utilizando s...
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - December 9, 2016 Category: Pathology Source Type: research

Histopathological study comparing native and post-transplant recurrent chronic hepatitis C with emphasis on confounders with acute cellular rejection
Conclusion: Histological findings in chronic hepatitis C are similar in non-transplant and post-transplant patients. In addition, morphological features characteristic of ACR are also observed in HCV infection of native livers as well as in the graft of patients with recurrent infection after transplantation.RESUMO Introdu ção: A análise histológica de biópsias hepáticas pós-transplante pode trazer dificuldades na distinção entre hepatite crônica C (HCC) recorrente e outras causas de disfunção do enxerto, sobretudo rejeição celular aguda (RCA). Objetivo: Comparar as características histológicas de bió ps...
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - December 9, 2016 Category: Pathology Source Type: research