How different animal models help us understand TRALI
Transfusion‐related acute lung injury (TRALI) is still one of the leading causes of transfusion‐associated mortality, despite increased awareness and the implementation of various mitigation strategies. TRALI may be either antibody or non‐antibody mediated. Understanding the underlying mechanism through clinical cases has been challenging because of the low and unpredictable incidence. Thus, animal models provide an important tool for investigating the mechanism of TRALI in a controlled and systematic fashion. One of the earliest animal models, an ex vivo rabbit lung model, revealed the role of anti‐5b (anti‐HNA...
Source: ISBT Science Series - March 6, 2018 Category: Hematology Authors: Y. L. Fung, J.P. Tung Tags: Congress Review Source Type: research
Major haemorrhage protocols
are aimed at optimizing the care of patients suffering life‐threatening bleeding. They should clearly set out the responsibilities of all of the staff involved including clinical and laboratory teams and other support staff with explicit lines of communication to support a prompt response without delays. The emphasis is on ready access to blood and components to limit coagulopathy in conjunction with definitive methods of controlling haemorrhage. High‐quality evidence for the early use of tranexamic acid strongly supports the inclusion of this drug in protocols for trauma and obstetric haemorrhage. Although national a...
Source: ISBT Science Series - March 6, 2018 Category: Hematology Authors: C. Booth, S. Allard Tags: Congress Review Source Type: research
Issue Information
ISBT Science Series,Volume 13, Issue 1, Page 1-2, February 2018. (Source: ISBT Science Series)
Source: ISBT Science Series - February 20, 2018 Category: Hematology Source Type: research
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ISBT Science Series,Volume 13, Issue 1, Page 1-2, February 2018. (Source: ISBT Science Series)
Source: ISBT Science Series - February 20, 2018 Category: Hematology Source Type: research
Issue Information
(Source: ISBT Science Series)
Source: ISBT Science Series - February 20, 2018 Category: Hematology Tags: Issue Information Source Type: research
Major applications and limitations of blood group genotyping in China
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - February 15, 2018 Category: Hematology Source Type: research
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ISBT Science Series, Ahead of Print. (Source: ISBT Science Series)
Source: ISBT Science Series - February 15, 2018 Category: Hematology Source Type: research
Quality monitoring and risk management in blood transfusion services
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - February 14, 2018 Category: Hematology Source Type: research
Role of CD36 in immune ‐mediated thrombocytopenia in Asian populations
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - February 14, 2018 Category: Hematology Source Type: research
Preparing your blood centre for accreditation
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - February 14, 2018 Category: Hematology Source Type: research
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ISBT Science Series, Ahead of Print. (Source: ISBT Science Series)
Source: ISBT Science Series - February 14, 2018 Category: Hematology Source Type: research
Preparing your blood centre for accreditation
Despite advance in medical treatment, blood supply is still an essential element in modern healthcare system with blood transfusion used in almost every clinical specialty. Adequacy, quality and safety are always the key focuses of concerns in most countries that measures have been taken to secure them. As in many other healthcare facilities, many countries have on its legislation to license the operation of blood centres (whether they are national, Red Cross or hospitals based) to provide the blood supply for clinical transfusion. The licensing requirement is based on their national health policy and law. Besides, like ho...
Source: ISBT Science Series - February 14, 2018 Category: Hematology Authors: A. Wong, Y. K. Yuen, C. K. Lee Tags: Congress Review Source Type: research
