Safe and sustainable plasmapheresis
ConclusionIn a time of increasing demand it is important to optimise immunoglobulin yield by retaining donors, increasing visit frequency and maximising volumes from each visit, whilst carefully balancing the risk of adverse reactions. Interventions must be assessed in terms of donor safety and also product yield. Both must be optimised if sustainability of plasma supply is to be achieved. (Source: ISBT Science Series)
Source: ISBT Science Series - August 1, 2017 Category: Hematology Authors: J. Pink, B. Bell, G. Kotsiou, S. Wright, J. Thyer Tags: Congress Review Source Type: research
Prevalence of Malaria in blood donor population from a tertiary care centre and effective donor notification and counselling policy
ConclusionBlood donors in our region have a 0·024% prevalence of malaria. With proper donor testing, notification and post‐test counselling the rate of TTM can be further minimized. (Source: ISBT Science Series)
Source: ISBT Science Series - August 1, 2017 Category: Hematology Authors: R. N. Makroo, S. Agrawal, M. Chowdhry, R. NL Tags: Original Paper Source Type: research
The role of the National Blood Transfusion Committee
Many countries have established national blood transfusion services in line with World Health Organization (WHO) guidelines and recommendations. However, according to WHO, few countries have developed policies and guidelines on the clinical use of blood and products which are being effectively implemented. This review outlines the WHO recommendations for a National Committee on the Clinical Use of Blood and describes the establishment of a National Blood Transfusion Committee (NBTC) in England and the first 16 years of its work. Although it is difficult to document the value of the NBTC with certainty, the improvements in ...
Source: ISBT Science Series - August 1, 2017 Category: Hematology Authors: M. F. Murphy, K. Pendry Tags: Congress Review Source Type: research
Impact of ABO ‐mismatch on outcome in bone marrow transplantation
ConclusionABO‐mismatch seems to be less frequent in Brazil. ABO‐mismatch had no significant impact on survival, neutrophil engraftment and VOD, but resulted in increased transfusion of RBC. (Source: ISBT Science Series)
Source: ISBT Science Series - August 1, 2017 Category: Hematology Authors: G. C. De Santis, R. O. Malta, A. C. Garcia ‐Silva, K. de L. Prata, M. C. Oliveira, D. A. Moraes, A. B. P. Stracieri, F. Pieroni, E. Z. Martinez, B. P. Simões, D. T. Covas Tags: Original Paper Source Type: research
Our older population: donors as well as recipients?
ConclusionsThere are more healthy older individuals than ever before. Many donors would like to continue donating into their eighth decade, and perhaps beyond. There is increasing evidence that donation is safe in older individuals, and that they can make a significant contribution to the blood supply. (Source: ISBT Science Series)
Source: ISBT Science Series - August 1, 2017 Category: Hematology Authors: M. Goldman, S. F. O'Brien Tags: Congress Review Source Type: research
Damage control resuscitation: how to use blood products and manage major bleeding in trauma
Exsanguination comprises 30% to 40% of mortality in trauma and is the leading cause of trauma mortality in civilian and military populations. Many different strategies have been suggested for the management of haemorrhage, but recently damage control resuscitation (DCR) and damage control surgery (DCS) have become mainstays of treatment. The main principles of DCR are permissive hypotension as well as prevention of the ‘lethal triad’ of acidosis, coagulopathy and hypothermia. Acidosis affects multiple physiologic processes as well as worsening coagulopathy. Hypothermia can worsen acidosis and cause coagulopathy. DCR is...
Source: ISBT Science Series - August 1, 2017 Category: Hematology Authors: A. K. Bommiasamy, M. A. Schreiber Tags: Congress Review Source Type: research
Issue Information
(Source: ISBT Science Series)
Source: ISBT Science Series - May 19, 2017 Category: Hematology Tags: Issue Information Source Type: research
Patient Blood Management initiatives on a global level: the results of an International Society of Blood Transfusion Survey
ConclusionPBM initiatives have been implemented to different degrees at hospitals around the world. (Source: ISBT Science Series)
Source: ISBT Science Series - May 17, 2017 Category: Hematology Authors: C. So ‐Osman, D. E. Wal, S. Allard, Tags: Original Paper Source Type: research
Red blood cell alloimmunisation: induction of immunity and potential mitigation strategies
Millions of RBC units are transfused throughout the world annually. Even though each RBC unit contains multiple foreign donor antigens, only a minority of transfusion recipients will develop detectable RBC alloantibodies. Some factors that influence humoral immune responsiveness to transfused RBCs are obvious, including the necessity of being exposed to a foreign antigen that the immune system can process and present. Mathematically, however, every RBC transfusion meets those criteria. Thus, it remains unclear why some patients form alloantibodies (‘responders’), while others may be transfused hundreds of times without...
Source: ISBT Science Series - May 1, 2017 Category: Hematology Authors: J. E. Hendrickson Tags: Congress Review Source Type: research
The cost of transfusing a unit of red blood cells: a costing model for Canadian hospital use
ConclusionThis study's in‐hospital costs of $243·10 summed with the $423·00 acquisition costs per unit PRBC from the blood supplier place the complete societal costs of one unit PRBCs at $666·10. This value is comparable, but lower than the majority of studies in the United States and Europe examining the societal costs of PRBCs. (Source: ISBT Science Series)
Source: ISBT Science Series - May 1, 2017 Category: Hematology Authors: O. Lagerquist, D. Poseluzny, G. Werstiuk, J. Slomp, M. Maier, S. Nahirniak, G. Clarke Tags: Original Paper Source Type: research
A follow ‐up survey of knowledge, attitudes and practices surrounding blood donation in Trinidad and Tobago
ConclusionThere was no significant change in community KAP between surveys. Anthropological studies into blood donation are needed to plan an effective revised and targeted blood donation campaign. Legal and regulatory changes must facilitate VNRD. (Source: ISBT Science Series)
Source: ISBT Science Series - May 1, 2017 Category: Hematology Authors: K. S. Charles, K. Chisholm, K. Gabourel, K. Philip, S. Ramdath, H. Abdul ‐Hakeem, A. Vaillant, S. Pooransingh, G. Legall, A. Chantry Tags: Original Article Source Type: research
Assembling a state ‐wide patient blood management program as a standard of care: the Western Australian experience
ConclusionKey elements of program success included appointment of hospital‐based PBM staff, establishment of multidisciplinary committees with support from enthusiastic clinical staff, data provision to hospital departments and the national and international context in which this work occurred. Lessons learned included overestimating the value of staff education and culture change alone. (Source: ISBT Science Series)
Source: ISBT Science Series - May 1, 2017 Category: Hematology Authors: T. Gallagher, M. F. Leahy, S. Darby, L. Campbell, R. Howman, S. Watts, M. Vodanovich, J. Tovey, A. Esson, A. Koay Tags: Original Paper Source Type: research
Automation in blood processing
ConclusionAutomation of blood component preparation from whole blood offers several advantages that include reduction of standard equipment, space, workload to lab staff as well as more standardized bloodcomponents. (Source: ISBT Science Series)
Source: ISBT Science Series - February 26, 2017 Category: Hematology Authors: Magdy El Ekiaby Tags: Invited Review Source Type: research
Issue Information
(Source: ISBT Science Series)
Source: ISBT Science Series - February 26, 2017 Category: Hematology Tags: Issue Information Source Type: research
Implementing a fully automated high ‐throughput strategy for blood donor genotyping
ConclusionsThe proposed fully automated genotyping strategy is accurate, fast and suitable for meeting the needs of a laboratory of molecular immunohematology. (Source: ISBT Science Series)
Source: ISBT Science Series - February 1, 2017 Category: Hematology Authors: C. L. Dinardo, J. V. Bianchi, M. R. Dezan, V. B. Oliveira, F. C. A. Gomes, A. J. O. Gallucci, J. E. Levi, J. E. Krieger, A. C. Pereira, H. C. Santos, H. Domingues, V. G. Rocha, A. Mendrone ‐Júnior, E. C. Sabino Tags: Original Paper Source Type: research
