The Association between Survival and the Pathologic Features of Periampullary Tumors Varies over Time.
Conclusions. Overall mortality was closely related to the LNR within the first year, while longer follow-up periods demonstrated a stronger association with perineural invasion and overall LN status. Therefore, the current staging for periampullary tumors may need to be updated to include the LNR.
PMID: 25104878 [PubMed] (Source: HPB Surgery)
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research
The Interaction between Diabetes, Body Mass Index, Hepatic Steatosis, and Risk of Liver Resection: Insulin Dependent Diabetes Is the Greatest Risk for Major Complications.
Conclusions. Liver surgery in the presence of steatosis, elevated BMI, and non-insulin dependent diabetes is not associated with major complications. Although diabetes requiring insulin therapy was a significant risk factor, the major risk factors relate to technical aspects of surgery, particularly synchronous bowel procedures.
PMID: 25202167 [PubMed] (Source: HPB Surgery)
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research
Iatrogenic biliary injuries: multidisciplinary management in a major tertiary referral center.
Conclusion. Management of biliary injuries was much better with multidisciplinary care team with initial minimal invasive technique to major surgery in major complex injury encouraging early referral to highly specialized hepatobiliary center.
PMID: 25435672 [PubMed] (Source: HPB Surgery)
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research
Use of Pharmacologic Agents for Modulation of Ischaemia-Reperfusion Injury after Hepatectomy: A Questionnaire Study of the LiverMetSurvey International Registry of Hepatic Surgery Units.
Conclusions. This is believed to be the first survey on the use of pharmacological agents to modify liver IR injury. The target population is clinicians involved in liver resection. The results show that pharmacological modulation is used by only a minority of respondents to this questionnaire and that when this treatment is selected, N-acetylcysteine is the most frequently used.
PMID: 25477707 [PubMed] (Source: HPB Surgery)
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research
Risk Factors Associated with Reoperation for Bleeding following Liver Transplantation.
Conclusion. Reoperation for bleeding following LTx was associated with increased resource utilization and recipient mortality. A lower threshold for intraoperative platelet transfusion and antifibrinolytics, especially in patients with high lab-MELD score, may decrease the incidence of reoperation for bleeding following LTx.
PMID: 25505820 [PubMed] (Source: HPB Surgery)
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research
Primary leiomyoma of the liver: a review of a rare tumour.
Conclusions. Primary leiomyoma of the liver is very rare tumour with complex pathogenesis which remains largely unknown. Imaging of the tumour does not allow for a tissue specific diagnosis; hence histological review of the tissue specimen and immunohistochemical stains are imperative for diagnosis. Surgical resection is both diagnostic and curative. The diagnosis of primary leiomyoma of the liver should be considered as a differential in the management of liver tumours.
PMID: 25505821 [PubMed] (Source: HPB Surgery)
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research
Laparoscopic versus Open Liver Resection: Differences in Intraoperative and Early Postoperative Outcome among Cirrhotic Patients with Hepatocellular Carcinoma-A Retrospective Observational Study.
Conclusions. Lower morbidity and mortality, maintenance of liver function, and shorter hospital stay suggest the safety and benefit of laparoscopic approach.
PMID: 25548432 [PubMed] (Source: HPB Surgery)
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research
The impact of changed strategies for patients with cholangiocarcinoma in this millenium.
Conclusion. Overall survival for individuals with PHC was better than for those with IHC. Over time survival in IHC patients improved but not in those with PHC.
PMID: 25788760 [PubMed] (Source: HPB Surgery)
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research
Surgery for cystic pancreatic lesions in the post-sendai era: a single institution experience.
Conclusion. Cystic pancreatic lesions are still a diagnostic challenge, requiring a dedicated multidisciplinary approach. The rate of malignancy is relatively small, whereas postoperative morbidity is substantial, underscoring the importance of adequate patient selection considering both the risk of surgery and the long term risk of malignancy.
PMID: 25873753 [PubMed] (Source: HPB Surgery)
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research
The changing spectrum of surgically treated cystic neoplasms of the pancreas.
Conclusion. There has been a dramatic change in surgically treated pancreatic cystic tumors over the past two decades. Our data suggests that the incorporation of new imaging and diagnostic tests has led to greater detection of cystic tumors and a decreased rate of potentially unnecessary resections. Therefore, all patients with cystic pancreatic lesions should undergo a focused CT-pancreas, and an EUS biopsy should be considered, in order to best select those that would benefit from surgical resection.
PMID: 25918455 [PubMed] (Source: HPB Surgery)
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research
Assessment of Liver Remnant Using ICG Clearance Intraoperatively during Vascular Exclusion: Early Experience with the ALIIVE Technique.
Conclusion. The novel ALIIVE technique is feasible and assesses actual future liver remnant function before the point of no return during major hepatectomy. This technique may be useful as a check step to offer a margin of safety to prevent posthepatectomy liver failure and death. Further confirmatory studies are required to determine a safety cutoff level.
PMID: 26106254 [PubMed] (Source: HPB Surgery)
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research
Feasibility of Comparing the Results of Pancreatic Resections between Surgeons: A Systematic Review and Meta-Analysis of Pancreatic Resections.
Conclusions. A valid risk prognostic model and a classification system of surgical complications are necessary before meaningful comparisons of the operative performance between pancreatic surgeons can be made.
PMID: 26351405 [PubMed] (Source: HPB Surgery)
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research
The Surgical Management of Concomitant Gallbladder and Common Bile Duct Stones.
Conclusions. Successful management of choledocholithiasis requires a breadth of laparoscopic and endoscopic expertise.
PMID: 26420916 [PubMed] (Source: HPB Surgery)
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research
Effect of the Human Amniotic Membrane on Liver Regeneration in Rats.
Conclusion. Applying the amniotic membrane to residual liver adversely affected liver regeneration. However, mesenchymal stem cell research has the potential to accelerate liver regeneration investigations.
PMID: 26457000 [PubMed] (Source: HPB Surgery)
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research
Preoperative Diagnostic Angiogram and Endovascular Aortic Stent Placement for Appleby Resection Candidates: A Novel Surgical Technique in the Management of Locally Advanced Pancreatic Cancer.
Conclusion. We propose this novel technique in the preoperative management of patients who are undergoing a modified Appleby procedure. While further experience with this technique is required, we believe that it confers significant advantages to the current standard of care.
PMID: 26491217 [PubMed] (Source: HPB Surgery)
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research
