Extended Perioperative Antibiotic Coverage in Conjunction with Intraoperative Bile Cultures Decreases Infectious Complications after Pancreaticoduodenectomy.
Conclusion. Prolonged perioperative antibiotic therapy in conjunction with intraoperative bile cultures decreases the short-term infectious complications of PD, with no significant increase in Clostridium difficile colitis incidence. PMID: 27147813 [PubMed] (Source: HPB Surgery)
Source: HPB Surgery - May 7, 2016 Category: Surgery Tags: HPB Surg Source Type: research

Quality of Life in Hepatocellular Carcinoma Patients Treated with Transarterial Chemoembolization.
Authors: Ahmed S, de Souza NN, Qiao W, Kasai M, Keem LJ, Shelat VG Abstract Hepatocellular carcinoma (HCC) is one of the most commonly diagnosed cancers worldwide. Majority of patients with HCC are diagnosed in the advanced stages of disease and hence they are only suitable for palliative therapy. TACE (transarterial chemoembolization) is the most commonly used treatment for unresectable HCC. It is however unclear if TACE improves the quality of life (QoL) in patients with HCC. The aim of this review is to evaluate the impact of TACE on QoL of HCC patients. PMID: 27143815 [PubMed] (Source: HPB Surgery)
Source: HPB Surgery - May 5, 2016 Category: Surgery Tags: HPB Surg Source Type: research

Diagnostic Laparoscopy with Ultrasound Still Has a Role in the Staging of Pancreatic Cancer: A Systematic Review of the Literature.
Conclusion. DLUS seems to still have a role in the preoperative staging of pancreatic cancer. With its ability to detect liver metastases, vascular involvement, and peritoneal metastases, the use of DLUS leads to less noncurative laparotomies. PMID: 27122655 [PubMed] (Source: HPB Surgery)
Source: HPB Surgery - April 29, 2016 Category: Surgery Tags: HPB Surg Source Type: research

The Role of Eugenol in the Prevention of Acute Pancreatitis-Induced Acute Kidney Injury: Experimental Study.
Conclusions. Eugenol administration was protective for the kidneys in an experimental model of acute pancreatitis in rats. PMID: 26884642 [PubMed] (Source: HPB Surgery)
Source: HPB Surgery - February 18, 2016 Category: Surgery Tags: HPB Surg Source Type: research

Hepatocellular Carcinoma in the Pediatric Population: A Population Based Clinical Outcomes Study Involving 257 Patients from the Surveillance, Epidemiology, and End Result (SEER) Database (1973-2011).
Conclusion. HCC is a rare pediatric malignancy that presents most often as an advanced tumor, >4 cm in Caucasian males. Children with HCC achieve significantly longer mean overall survival compared to adults with HCC, primarily attributable to the more favorable fibrolamellar histologic variant, and more aggressive surgical intervention, which significantly improves survival. PMID: 26663981 [PubMed] (Source: HPB Surgery)
Source: HPB Surgery - December 18, 2015 Category: Surgery Tags: HPB Surg Source Type: research

Gallstone ileus of the sigmoid colon: an unusual cause of large-bowel obstruction.
We describe the case of a 92-year-old man who presented with symptoms and signs of large-bowel obstruction. Radiological investigation showed a large gallstone impacted in the sigmoid colon. Open enterolithotomy was undertaken relieving the obstruction and the patient made a full recovery. PMID: 20585361 [PubMed - indexed for MEDLINE] (Source: HPB Surgery)
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research

Indications and early outcomes for total pancreatectomy at a high-volume pancreas center.
CONCLUSION: Total pancreatectomy is definitely indicated for a limited range of elective and emergency situations. Indications can be: size or localisation of pancreatic tumor, trouble, technical diffuculties and therapy-refractory pain in chronic pancreatitis. A TP due to perioperative complications (troubles) after pancreatic resections is doomed by extremely high morbidity and mortality and should be avoided. PMID: 20689708 [PubMed - indexed for MEDLINE] (Source: HPB Surgery)
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research

Cyberknife stereotactic body radiation therapy for nonresectable tumors of the liver: preliminary results.
CONCLUSION: Our preliminary results showed that SBRT is a safe and effective local treatment modality in selected patients with liver malignancies with minimal adverse events. Further studies are needed to define its role in the management of these malignancies. PMID: 20689733 [PubMed - indexed for MEDLINE] (Source: HPB Surgery)
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research

Hepatic haemangioma masquerading as the gallbladder in a case of gallbladder agenesis: a case report and literature review.
We describe the first documented case of gallbladder agenesis where the clinical presentation was consistent with biliary colic, and radiological investigation suggested the presence of gallstones. Subsequent operative findings revealed a solitary haemangioma of the liver sited in the normal position of the gallbladder fossa but with absence of the gallbladder. It is important that clinicians should keep gallbladder agenesis in mind when the gallbladder appears abnormal on preoperative imaging studies and cannot be found at laparoscopy. As symptoms will improve in 98% of cases, it is very important to avoid unnecessary int...
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research

Life-saving super-urgent liver transplantation with replacement of retrohepatic vena cava by dacron graft.
We describe a modified technique of side-to-side cavo-cavostomy by Dacron interposition prosthesis during a super urgent liver transplantation. A liver graft from a deceased donor was immediately requested on a top priority basis as a consequence of massive bleeding during extended left hepatectomy for a huge hepatic haemangioma arising from the caudate lobe. Veno-venous bypass was employed during anhepatic phase but it was disconnected due to severe fibrinolysis and hypothermia. A porto-caval shunt was performed and the inferior vena cava outflow was restored by a Dacron interposition prosthesis. A liver graft from a dece...
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research

Metronidazole-induced pancreatitis.
CONCLUSION: This case provides the eighth report of Metronidazole induced pancreatitis. All of the cases were reported in females and ran a benign course. Early diagnosis, discontinuation of the drug and supportive care will lead to a successful recovery in the majority of cases. PMID: 20862338 [PubMed - indexed for MEDLINE] (Source: HPB Surgery)
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research

Hepatectomy for hepatocellular carcinoma complicated by vasculitis flare.
CONCLUSION: Cryoglobulinemia is associated with hepatitis C and may complicate the care of this patient population. The treatment of cryoglobulinemia posthepatectomy patients is complicated by concerns over how medications may affect the regenerating liver. Steroids should be used with caution in this setting. SUMMARY: Brief report of hepatectomy complicated by vasculitis in the context of hepatocellular carcinoma secondary to hepatitis C addresses the management of mixed cryoglobulinemia in post-hepatectomy patients. PMID: 20862343 [PubMed - indexed for MEDLINE] (Source: HPB Surgery)
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research

Radiomorphology of the Habib sealer-induced resection plane during long-time followup: a longitudinal single center experience after 64 radiofrequency-assisted liver resections.
CONCLUSION: Liver resection utilizing radiofrequency-induced resection plane coagulation is a safe alternative to the established resection techniques. The residual zone of coagulation necrosis remains basically unchanged during a followup of three years. This has to be kept in mind when evaluating the follow up imaging of these patients. PMID: 20862384 [PubMed - indexed for MEDLINE] (Source: HPB Surgery)
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research

Eosinophilic cholangitis and cholangiopathy: a sheep in wolves clothing.
CONCLUSION: EC is a rare form of biliary obstruction which can masquerade as a malignancy. Unlike cholangiocarcinoma, EC occurs more commonly in younger patients and in men. Most patients will require surgical treatment. PMID: 21076681 [PubMed - indexed for MEDLINE] (Source: HPB Surgery)
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research

An unusual zoonosis: liver abscess secondary to asymptomatic colonic foreign body.
Authors: Gundara JS, Harrison R Abstract A liver abscess may arise following any insult to gut integrity allowing portal drainage of bacteria to hepatocytes. Foreign bodies such as bones, toothpicks and items of stationery have previously been implicated in compromising gut epithelium. Here we present the case of a 57 year old man suffering from a left liver abscess. This was defined on CT which incidentally also identified a chicken bone protruding through the wall of the distal sigmoid colon. Whilst unwell with upper abdominal pain and sepsis, the presumed source of portal sepsis within the colon remaine...
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research