Primary retroperitoneal paraganglioma simulating a pancreatic mass: a case report and review of the literature.
Authors: Sangster G, Do D, Previgliano C, Li B, LaFrance D, Heldmann M Abstract Paragangliomas are extra-adrenal tumors of the autonomic nervous system and may be found within the skull base, neck, chest, and abdomen. When presenting within the abdominal cavity, they may arise as a primary retroperitoneal neoplasm and can mimic vascular malformations or other conditions related to specific retroperitoneal organs such as the pancreas, kidneys, or adrenals. Retroperitoneal paragangliomas are mostly benign with good prognosis; however, they can present with abdominal pain, palpable mass, or hypertensive episo...
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research

Pleomorphic giant cell carcinoma of the pancreas with hepatic metastases--initially presenting as a benign serous cystadenoma: a case report and review of the literature.
CONCLUSION: This unusual case highlights the challenges in managing pancreatic cystic lesions and emphasizes the importance of considering less common forms of pancreatic cystic masses when the findings are atypical for the presentation. Surgical excision in these cases over conservative steps may be the most appropriate management. PMID: 21197435 [PubMed - indexed for MEDLINE] (Source: HPB Surgery)
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research

Pancreatic resections for advanced M1-pancreatic carcinoma: the value of synchronous metastasectomy.
CONCLUSION: Pancreatic resection for M1 periampullary cancer of the pancreas can be performed safely in well-selected patients. However, indication for surgery has to be made on an individual basis. PMID: 21197481 [PubMed - indexed for MEDLINE] (Source: HPB Surgery)
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research

Is there a learning curve for pancreaticoduodenectomy after fellowship training?
CONCLUSION: Even with extensive training in pancreatic surgery, a learning curve exists for the performance of PD. With experience, improvements were made in operative time, but more importantly in patient outcomes including length of stay and receipt of adjuvant therapy. PMID: 21318116 [PubMed] (Source: HPB Surgery)
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research

A solid pseudopapillary tumour arising from mesocolon without ectopic pancreas.
Authors: Tez M, Ozalp N, Zülfikaroğlu B, Koç M Abstract A solid pseudopapillary tumour (SPT) is an uncommon pancreatic tumour. Very rarely it has also been described outside the pancreas, usually arising from heterotopic pancreatic tissue. In this paper, we described a case arising from the transverse mesocolon without heterotopic pancreatic tissue in an 18-year-old girl. PMID: 21318131 [PubMed] (Source: HPB Surgery)
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research

Sonographic diagnosis of arterioportal fistula.
CONCLUSION: In summary; both of the artery and vein related with fistula were wider than normal and seen as adjacent anechoic circles, there was an aneurysmatic dilation on vein which has turbulent flow within it, the communication between the artery and aneurysm can be seen sonographically, both of the vessels have arterial flow, filling of the vein was retrograde and other branches of the artery and vein unrelated with aneurysm were all normal in dimension. PMID: 21318158 [PubMed] (Source: HPB Surgery)
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research

The dynamics of glutathione species and ophthalmate concentrations in plasma from the VX2 rabbit model of secondary liver tumors.
CONCLUSION: Disturbances in the oxidoreductive state of livers appear to be a surrogate of early tumor growth. PMID: 21350723 [PubMed] (Source: HPB Surgery)
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research

Pancreatic serous cystadenoma with compression of the main pancreatic duct: an unusual entity.
We describe a patient, whose pancreatic cyst exhibited a radiological appearance distinct from that of typical serous cystadenoma, resulting in diagnostic difficulties. CT and MRI showed a 10 cm-polycystic tumor with upstream dilatation of the main pancreatic duct (MPD), suggestive of intraductal papillary mucinous tumor (IPMT). Ultrasonographic aspect and EUS-guided fine-needle aspiration gave arguments for serous cystadenoma. ERCP showed a communication between cysts and the dilated MPD, compatible with IPMT. The patient underwent left pancreatectomy with splenectomy. Pathological examination concluded in a serous cyst...
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research

The effects of L-arginine on liver damage in experimental acute cholestasis an immunohistochemical study.
This study shows that, after 7 days of biliary obstruction, liver damage is well established and exogenous L-arginine treatment partially but significantly prevented the liver injury in acute cholestasis. PMID: 21760660 [PubMed] (Source: HPB Surgery)
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research

A Malignant Gastrointestinal Stromal Tumor of the Gallbladder Immunoreactive for PDGFRA and Negative for CD 117 Antigen (c-KIT).
We present for the first time a malignant gastrointestinal stromal tumor of the gallbladder, immunoreactive for platelet-derived growth factor receptor alpha (PDGFRA) and negative for CD 117 antigen (c-KIT). PMID: 21760661 [PubMed] (Source: HPB Surgery)
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research

Laparoscopic management for carcinoid metastasis to the spleen.
We report a rare case of a laparoscopic splenectomy performed for a carcinoid metastasis. The patient represented with pleuritic left-sided chest pain from pleural deposits 9 years following resection of a primary lung carcinoid tumour. They were found to have a 4.7 cm splenic lesion on CT with a probable left acetabular metastasis demonstrated on Gallium PET scan. The patient underwent laparoscopic splenectomy for debulking treatment of the splenic lesion that was confirmed to be a splenic metastasis of the resected carcinoid lung tumour. Following an uncomplicated recovery, the patient was discharged on the second post...
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research

Endopancreatic bile duct cholangiocarcinoma in a patient with peutz-jeghers syndrome.
Authors: Charalabopoulos AK, Krivan SP, Machairas NA, Misiakos EP, Machairas AN Abstract Peutz-Jeghers syndrome is a rare autosomal dominant inherited disease characterized by a special type of hamartomatous gastrointestinal polyps combined with mucocutaneous melanin pigmentations. Patients with the syndrome have a high risk of developing neoplasia, with colon, small bowel, and stomach being the most common gastrointestinal sites. Herein, we present the occurrence of a rare tumor in patients with Peutz-Jeghers syndrome; a cholangiocarcinoma of the endopancreatic bile duct. A minireview is also presented. I...
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research

Comparison of staging systems of hepatocellular carcinoma.
This study aims to evaluate various commonly used staging systems of HCC. Patients who underwent surgery during 2001-2007 were included. All patient data were retrospectively staged using six staging systems, that are American Joint Committee on Cancer (AJCC) Tumour-Node-Metastasis (TNM), Okuda staging, Cancer of the Liver Italian Program (CLIP), Barcelona Clinic Liver Cancer (BCLC), Chinese University Prognostic Index (CUPI), and Japan Integrated Staging (JIS). Child-Pugh classification was also evaluated. The staging systems were compared by mean of overall and disease-free survival. Total of 99 patient data were enrolle...
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research

A Case of Hemorrhagic Necrosis of Ectopic Liver Tissue within the Gallbladder Wall.
Authors: Nagar S, Koffron A, Raofi V Abstract Ectopic liver tissue is a rare clinical entity that is mostly asymptomatic and found incidentally. In certain situations, however, patients may present with symptoms of abdominal pain secondary to torsion, compression, obstruction of adjacent organs, or rupture secondary to malignant transformation. Herein, we report a case of a 25-year-old female that presented with acute onset of epigastric pain found to have ectopic liver tissue near the gallbladder complicated by acute hemorrhage necessitating operative intervention in the way of laparoscopic excision and c...
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research

A novel classification system to address financial impact and referral decisions for bile duct injury in laparoscopic cholecystectomy.
Conclusion. We have presented a simple classification system that is able to accurately predict cost and need for surgical repair. PMID: 21912446 [PubMed] (Source: HPB Surgery)
Source: HPB Surgery - October 29, 2015 Category: Surgery Tags: HPB Surg Source Type: research