6 Mechanical circulatory support programme at chiba university hospital, japan
Management of advanced (ACC Stage D) heart failure remains a major challenge. Left ventricular assist system (LVAS) has been applied with increasing frequency and support duration. Three types of implantable device (HeartMate II, Jarvik 2000, and EVAHEART) are currently available as bridge-to-transplant in Japan. As serious shortage of donor organs is limiting the number of heart transplantation (approximately 50 cases per year), the mean waiting period for devices has exceeded 1000 days. Although survival rate is acceptable (92% at 1 year, 84% at 3 years), there still exists several limitations including infection, thromb...
Source: Heart Asia - April 9, 2018 Category: Cardiology Authors: Matsumiya, G. Tags: APAHFF Abstracts 2017 Source Type: research

5 mechanical circulatory support programme: experience in hong kong
Conclusion LVAD therapy as BTT has become the standard therapy for potential heart transplant candidates in Hong Kong and its role as DT is also emerging. Timely recognition and referral is the key to achieve the best outcome in this sick patient population. (Source: Heart Asia)
Source: Heart Asia - April 9, 2018 Category: Cardiology Authors: Wong, K., Cally, H., Ko, Y., Au, T. W., Katherine, F., Shing, L. K. Tags: APAHFF Abstracts 2017 Source Type: research

4 Bridges to transplant
Heart transplantation remains the gold standard treatment for end-stage heart failure. By definition, these patients are unwell, and unfortunately a proportion will die waiting for transplant. The journey to transplantation is usually characterised by recurrent hospitalisations and may be complicated by progressive organ dysfunction. Optimisation of patient outcomes involves upward titration of evidence-based therapy (Ponikowski, et al. 2016), however, in this cohort treatment is often gradually withdrawn due to patient hypotension, renal dysfunction or other organ failure (Baumwol, 2017). Intermittent diuretic therapy has...
Source: Heart Asia - April 9, 2018 Category: Cardiology Authors: Hayward, C. S. Tags: APAHFF Abstracts 2017 Source Type: research

3 Experience of LVAD as destination therapy at ramathibodi hospital, bangkok
Setting up a new left ventricular assist device (LVAD) centre in a low-income country is challenging. Here we present our first case of long-term LVAD as destination therapy. The case illustrated the team effort and importance of the Heart Failure Team (heart failure cardiologists, cardiothoracic surgeons and VAD coordinators), nursing services, hospital administrators and other supportive services (nutrition, social services, physical/rehabilitation services, and finance and data management). In brief, this was a case of a 74-year-old gentleman who had suffered from ischaemic cardiomyopathy (LVEF 22%) and had been hospita...
Source: Heart Asia - April 9, 2018 Category: Cardiology Authors: Yingchoncharoen, T. Tags: APAHFF Abstracts 2017 Source Type: research

2 The challenges and triumphs of establishing a heart failure programme in singapore
Heart failure (HF) is a major global healthcare problem with an estimated prevalence of approximately 26 million. In Asia-Pacific regions, HF is associated with a significant socioeconomic burden and high rates of hospital admission.1 2 Though undesirable, hospitalisation is an opportunity to optimise HF therapy and advise clinicians and patients about the importance of continued adherence to HF medication and regular monitoring. Epidemiological data that could help to improve management approaches to address this burden in Asia-Pacific regions are limited, but suggest patients with HF in the Asia-Pacific are younger and h...
Source: Heart Asia - April 9, 2018 Category: Cardiology Authors: Sim, D. K. Tags: APAHFF Abstracts 2017 Source Type: research

1 Heart function replacement: the current state and a look into the future
There is an epidemic of advanced heart failure across developed countries. For those who are refractory to medical and/or device therapies, cardiac replacement can improve quality of life and life expectancy. Fifty years on from the first successful human case, heart transplantation remains the most effective treatment for advanced heart failure with <5% 30 day post-transplant mortality and median survival approaching 14 years. However, there is a severe shortage of suitable donor hearts. Conventionally, only hearts from donation after brain dead (DBD) are considered for transplantation. After careful assessment, 25% to...
Source: Heart Asia - April 9, 2018 Category: Cardiology Authors: Tsui, S. S. Tags: APAHFF Abstracts 2017 Source Type: research

Cardiac surgery risk scoring systems: In quest for the best
Over the last 3 decades, there has been a profusion in the number of cardiac surgery risk score systems available (approximately 20 in current adult cardiac surgery literature).1 One common factor in these scoring systems is that they have all been proposed from either North America or Europe.1 The field of cardiac surgery is continuously evolving with changes in surgical indications, spectrum of diseases, surgical expertise, perioperative management and extensiveness of surgical audit. Consequently, newer scoring systems have been regularly published with the common objective of predicting surgical mortality and more...
Source: Heart Asia - April 4, 2018 Category: Cardiology Authors: Hote, M. Tags: Intensive care Editorial Source Type: research

Dilated superior vena cava in fetal echocardiographic three-vessel view: what lies ahead?
A 38-year-old woman, 37+3 weeker was incidentally detected to have fetal cardiomegaly during 36 weeks ultrasound and referred for fetal echocardiogram. Antenatal history and anomaly scan were normal. Fetal echocardiogram showed heart rate of 153/min, sinus rhythm, situs solitus, levocardia, dilated right atrium and ventricle with venoatrial, atrioventricular and ventriculoarterial concordances. All cardiac valves were normal; cardiac crux was intact with separate mitral and tricuspid annuli (figure 1A–C and online supplementary video 1supplementary video 1). Mild tricuspid regurgitation with peak velocity of 1.77&nbs...
Source: Heart Asia - March 29, 2018 Category: Cardiology Authors: Chaudhuri, M., V, S., Iyengar, S. S. Tags: Image challenge Source Type: research

Contrast-induced encephalopathy after coronary angioplasty in a patient with ST-elevation myocardial infarction
A 75-year-old man with a history of diabetes mellitus presented with chest pain. He was diagnosed with acute ST-elevation myocardial infarction. Emergent coronary angiography revealed proximal left anterior descending (LAD) artery occlusion. Primary percutaneous coronary intervention (PCI) was then performed. During aspiration thrombectomy, he went into cardiopulmonary arrest. Cardiopulmonary resuscitation (CPR) was started immediately. Recovery of spontaneous circulation was obtained after 7 min of CPR while PCI of the LAD was being performed simultaneously. A drug-eluting stent was deployed over the culprit lesion and th...
Source: Heart Asia - March 6, 2018 Category: Cardiology Authors: Hirata, S., Koga, M., Iseki, H. Tags: Images in cardiovascular medicine Source Type: research

Prognostic value of soluble ST2 postaortic valve replacement: a meta-analysis
Conclusions sST2 significantly predicts all-cause mortality in patients who have undergone AVR, but this conclusion is limited by the small number of patients. Larger prospective studies are required to better elucidate its value for risk stratification in this patient population. (Source: Heart Asia)
Source: Heart Asia - March 6, 2018 Category: Cardiology Authors: Tse, G., Ip, C., Luk, K. S., Gong, M., Ting, Y. Y., Lakhani, I., Bazoukis, G., Li, G., Letsas, K. P., Dong, M., Liu, T., Wong, M. C. S. Tags: Epidemiology Original research Source Type: research

Empirical embolisation for intermittent spontaneous muscle haemorrhage associated with anticoagulation therapy
As more patients are receiving anticoagulant therapy, spontaneous muscle haemorrhage (SMH) has become a common, potentially life-threatening complication.1 2 However, no standardised approach for SMH has established and intermittent SMH is challenging to manage because of lack of reports. A 77-year-old man with a history of double mechanical heart valve replacement and chronic atrial fibrillation on warfarin complained of sudden onset of painful swelling in the left leg. Contrast-enhanced computed tomography (CT) revealed femoral and crural muscle haemorrhage (figure 1A) despite a moderate intensity of anticoagulation (Pro...
Source: Heart Asia - March 2, 2018 Category: Cardiology Authors: Sawada, K., Kawarada, O., Yasuda, S. Tags: Images in cardiovascular medicine Source Type: research

East meets West: the influence of racial, ethnic and cultural risk factors on cardiac surgical risk model performance
Conclusion SinoSCORE demonstrated limited discrimination when applied to an American population. The derived SinoSCORE had a discrimination comparable with that of the STS, suggesting underlying similarities of physiological substrate undergoing surgery. However, differential influence of various risk factors suggests that there may be varying degrees of importance and interactions between risk factors. Clinicians should exercise caution when applying risk models across varying populations due to potential differences that racial, ethnic and geographic factors may play in cardiac disease and surgical outcomes. (Source: Heart Asia)
Source: Heart Asia - February 27, 2018 Category: Cardiology Authors: Soo-Hoo, S., Nemeth, S., Baser, O., Argenziano, M., Kurlansky, P. Tags: Epidemiology Original research Source Type: research

Thank you to our reviewers 2017
The Editor would like to publicly acknowledge the people listed below who served as reviewers on the journal during 2017. Without their efforts, the quality of the journal could not be sustained. Andrea Barajas-Nava, Leticia Arava, Sudheer Barbaro, Giuseppe Beaton, Andrea Benezet-Mazuecos, Juan Bhargava, Balram Brunetti, Natale D Chaturvedi, Vivek Chen, Fang Choudhary, Shiv Chow, Clara K Correia, Emanuel Corsi, Daniel J D’ascenzi, Flavio Devasenapathy, Niveditha Dharmarajan, Kumar Du, Xue Eikelboom, John W Fang, Fang Gamra, Habib Giardina, Elsa Goto, Tadahiro Gross, G J Gupta, Saurabh Harrison, James Haskard, Dorian ...
Source: Heart Asia - February 9, 2018 Category: Cardiology Tags: Thank you to our reviewers Source Type: research

Patient preferences for types of community-based cardiac rehabilitation programme
Conclusion This is the first study to explore patients’ preferences for different types of community CR. Higher income patients prefer physiotherapist presence and are willing to settle for less equipment. Our study serves as a guide for designing future community-based CR programmes. (Source: Heart Asia)
Source: Heart Asia - January 26, 2018 Category: Cardiology Authors: Chia, S., Wong, X. Y., Toon, M. L., Seah, Y., Yap, A. F., Lim, C., Tay, H. Y., Fong, W., Low, L. L., Kwan, Y. H. Tags: Original research Source Type: research

Acute myocardial infarction in a young male
An 18-year-old male presented with history of road traffic accident leading to multiple facial and skull bone fractures. There was no intracranial haemorrhage or active blood loss from any site. There was no evidence of chest injury. On examination he had tachycardia and persistent hypotension. An ECG revealed ST elevation in leads I, aVL, V1 and V2 with q right bundle branch block  (qRBBB) pattern suggestive of acute anterior wall myocardial infarction. Echocardiogram showed severe left ventricular dysfunction with regional wall motion abnormalities in left anterior descending artery (LAD) and left circumflex artery ...
Source: Heart Asia - January 23, 2018 Category: Cardiology Authors: Dubey, G., Jain, S. Tags: Images in cardiovascular medicine Source Type: research