The effect of metoprolol succinate on the cardiac function of patients with thalassaemia cardiomyopathy: a double-blind randomised study
Conclusions
Metoprolol succinate as a β-blocker may have the potential to significantly improve systolic function in patients with TCM and reverse LV remodelling to the same extent as in other types of cardiomyopathy.
Trial registration number
NCT01863173. (Source: Heart Asia)
Source: Heart Asia - April 17, 2014 Category: Cardiology Authors: Kojury, J., Zolghadrasli, A., Karimi, M., Babaee Beighi, M. A., Namazi, S. Tags: Original research Source Type: research
Interferon-{alpha} and pericardial injury: a case report and literature review
Interferon- α (IFN-α) alone or in combination with other chemotherapeutic agents has been used in the management of many malignant and non-malignant conditions. Pericarditis with or without pericardial effusion has been reported with IFN-α therapy, and available literature is limited to case reports. Pericardial constriction after interferon use has not been described in the published literature to date. We performed a systematic review of literature to address the demographic features, clinical presentation, diagnosis, treatment and outcome of interferon-related pericardial injury. (Source: Heart Asia)
Source: Heart Asia - April 16, 2014 Category: Cardiology Authors: Hakim, F. A., Singh, S., Pandit, A., Alegria, J. R., Camoriano, J., Stanton, M. L., Mookadam, F. Tags: Original research Source Type: research
ECG in severe hyperkalaemia: pacemaker doesn't matter so much
Case 1: A 51-year-old man with diabetes was referred for primary angioplasty with the working diagnosis of inferior ST elevation infarction. He denied chest pain but presented with severe diarrhoea in the previous days with obnubilation. ECG showed widened QRS complexes followed by peaked T waves with a shortened QT interval, P waves were not discernible (figure 1A). Blood analysis confirmed severe hyperkalaemia (K+ 9.4 mmol/L) due to acute renal failure (serum creatinine 15.7 mg/dL), without signs of ketoacidosis. Troponin I was normal. After infusion of calcium gluconate, higher heart rate and narrower QRS comp...
Source: Heart Asia - March 18, 2014 Category: Cardiology Authors: Cecconi, A., Franco Diez, E., Gomez de Diego, J. J., Nunez Gil, I. Tags: Images in cardiovascular medicine Source Type: research
An update on coronary bypass graft intervention
Coronary artery bypass grafting (CABG) remains one of the most common surgical procedures. In spite of great advancements like arterial grafts and off-pump bypass procedure, recurrent ischaemia may ensue with the lesions of the graft. Early postoperative ischaemia (<30 days) is due to graft occlusion or stenosis, and percutaneous coronary intervention (PCI) is frequently feasible. Late postoperative ischaemia (>3 years) is most often due to a saphenous vein graft (SVG) lesion. Multiple diseased grafts, reduced left ventricular function, and available arterial conduits favour repeat CABG, whereas, a patent l...
Source: Heart Asia - March 6, 2014 Category: Cardiology Authors: Dash, D. Tags: Review in cardiovascular technology Source Type: research
Atrial fibrillation in ventricular-paced rhythm: under-recognised, underdiagnosed and potentially dangerous
Conclusions
Our study demonstrates severe systemic under-recognition of this fairly common condition among hospital doctors. This may lead to a lower rate of anticoagulation and a higher incidence of thromboembolic events (Source: Heart Asia)
Source: Heart Asia - February 28, 2014 Category: Cardiology Authors: Alkhalil, M., Prabhavalkar, S., Cromie, N. Tags: Original research Source Type: research
