Evidence-Based Child Health: A Cochrane Review Journal This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

The Cochrane Library and safety of systemic corticosteroids for acute respiratory conditions in children: an overview of reviews
Abstract BackgroundAcute respiratory conditions are a leading cause of childhood morbidity and mortality. Corticosteroids are effective and established treatments in some acute respiratory infections (e.g. croup) and asthma exacerbations; however, their role is controversial in other conditions owing to inconsistent effectiveness or safety concerns (e.g. bronchiolitis, acute wheeze). ObjectivesTo examine clinically relevant short‐term safety outcomes related to acute single or recurrent systemic short‐term (<2 weeks) corticosteroid use based on systematic reviews of acute respiratory conditions. MethodsWe searched t...
Source: Evidence-Based Child Health: A Cochrane Review Journal - September 19, 2014 Category: Pediatrics Authors: Ricardo M. Fernandes, Marta Oleszczuk, Charles R. Woods, Brian H. Rowe, Christopher J. Cates, Lisa Hartling Tags: Overview of Reviews Source Type: research

Cochrane in context: Combined and alternating paracetamol and ibuprofen therapy for febrile children
Abstract Cochrane Review: Combined and alternating paracetamol and ibuprofen therapy for febrile children Wong T, Stang AS, Ganshorn H, Hartling L, Maconochie IK, Thomsen AM, Johnson DW. Combined and alternating paracetamol and ibuprofen therapy for febrile children. Cochrane Database of Systematic Reviews 2013, Issue 10. Art. No.: CD009572. DOI: 10.1002/14651858.CD009572.pub2 This companion piece to the review, “Combined and alternating paracetamol and ibuprofen therapy for febrile children,” contains the following pieces: The abstract of the review A commentary from one or more of the review authors, explaining w...
Source: Evidence-Based Child Health: A Cochrane Review Journal - September 19, 2014 Category: Pediatrics Authors: Tiffany Wong, Antonia S. Stang, Heather Ganshorn, Lisa Hartling, Ian K. Maconochie, Anna M. Thomsen, David W. Johnson Tags: Commentary Source Type: research

Combined and alternating paracetamol and ibuprofen therapy for febrile children
Abstract BackgroundHealth professionals frequently recommend fever treatment regimens for children that either combine paracetamol and ibuprofen or alternate them. However, there is uncertainty about whether these regimens are better than the use of single agents, and about the adverse effect profile of combination regimens. ObjectivesTo assess the effects and side effects of combining paracetamol and ibuprofen, or alternating them on consecutive treatments, compared with monotherapy for treating fever in children. Search methodsIn September 2013, we searched Cochrane Infectious Diseases Group Specialized Register; Cochran...
Source: Evidence-Based Child Health: A Cochrane Review Journal - September 19, 2014 Category: Pediatrics Authors: Tiffany Wong, Antonia S Stang, Heather Ganshorn, Lisa Hartling, Ian K Maconochie, Anna M Thomsen, David W Johnson Tags: Intervention Review Source Type: research

Cochrane in context: Probiotics for prevention of necrotizing enterocolitis in preterm infants
Abstract Cochrane Review: Probiotics for prevention of necrotizing enterocolitis in preterm infants AlFaleh K, Anabrees J. Probiotics for prevention of necrotizing enterocolitis in preterm infants. Cochrane Database of Systematic Reviews 2014, Issue 4. Art. No.: CD005496. DOI: 10.1002/14651858.CD005496.pub4. This companion piece to the review, “Probiotics for prevention of necrotizing enterocolitis in preterm infants,” contains the following pieces: The abstract of the review A commentary from Joan Robinson, editor‐in‐chief for Evidence‐Based Child Health, discussing the importance of this review A review o...
Source: Evidence-Based Child Health: A Cochrane Review Journal - September 19, 2014 Category: Pediatrics Authors: Joan Robinson Tags: Commentary Source Type: research

Probiotics for prevention of necrotizing enterocolitis in preterm infants
Abstract BackgroundNecrotizing enterocolitis (NEC) and nosocomial sepsis are associated with increased morbidity and mortality in preterm infants. Through prevention of bacterial migration across the mucosa, competitive exclusion of pathogenic bacteria, and enhancing the immune responses of the host, prophylactic enteral probiotics (live microbial supplements) may play a role in reducing NEC and the associated morbidity. ObjectivesTo compare the efficacy and safety of prophylactic enteral probiotics administration versus placebo or no treatment in the prevention of severe NEC or sepsis, or both, in preterm infants. Search ...
Source: Evidence-Based Child Health: A Cochrane Review Journal - September 19, 2014 Category: Pediatrics Authors: Khalid AlFaleh, Jasim Anabrees Tags: Intervention Review Source Type: research

Cochrane in context: Pharmacological interventions for hypertension in children
Abstract Cochrane Review: Pharmacological interventions for hypertension in children Chaturvedi S, Lipszyc DH, Licht C, Craig JC, Parekh RS. Pharmacological interventions for hypertension in children. Cochrane Database of Systematic Reviews 2014, Issue 2. Art. No.: CD008117. DOI: 10.1002/14651858.CD008117.pub2. This companion piece to the review, “Pharmacological interventions for hypertension in children,” contains the following pieces: The abstract of the review A commentary from one or more of the review authors, explaining why the review team felt the review was an important one to produce A review of clinica...
Source: Evidence-Based Child Health: A Cochrane Review Journal - September 19, 2014 Category: Pediatrics Authors: Swasti Chaturvedi, Deborah H. Lipszyc, Christoph Licht, Jonathan C. Craig, Rulan S. Parekh Tags: Commentary Source Type: research

Pharmacological interventions for hypertension in children
Abstract BackgroundHypertension is a major risk factor for stroke, coronary artery disease and kidney damage in adults. There is a paucity of data on the long‐term sequelae of persistent hypertension in children, but it is known that children with hypertension have evidence of end organ damage and are at risk of hypertension into adulthood. The prevalence of hypertension in children is rising, most likely due to a concurrent rise in obesity rates. In children with hypertension, non‐pharmacological measures are often recommended as first‐line therapy, but a significant proportion of children will eventually require ph...
Source: Evidence-Based Child Health: A Cochrane Review Journal - September 19, 2014 Category: Pediatrics Authors: Swasti Chaturvedi, Deborah H Lipszyc, Christoph Licht, Jonathan C Craig, Rulan Parekh Tags: Intervention Review Source Type: research

Glucocorticoids for bronchiolitis—should they be used?
Abstract Eco‐paediatrics is an occasional feature in Evidence‐Based Child Health: A Cochrane Review Journal. Our goal is to contribute to the worldwide discussion on reducing waste in health care. In each instalment, we will select a recent Cochrane review highlighting a practice, still in use, which the available evidence tells us should be discontinued. (Source: Evidence-Based Child Health: A Cochrane Review Journal)
Source: Evidence-Based Child Health: A Cochrane Review Journal - September 19, 2014 Category: Pediatrics Authors: Eyal Cohen Tags: Eco‐Paediatrics Source Type: research

An issue full of issues
(Source: Evidence-Based Child Health: A Cochrane Review Journal)
Source: Evidence-Based Child Health: A Cochrane Review Journal - September 19, 2014 Category: Pediatrics Authors: Joan Robinson Tags: Editorial Source Type: research

Issue Information
(Source: Evidence-Based Child Health: A Cochrane Review Journal)
Source: Evidence-Based Child Health: A Cochrane Review Journal - September 1, 2014 Category: Pediatrics Tags: Issue Information Source Type: research

Systematic reviews, overviews of reviews and comparative effectiveness reviews: a discussion of approaches to knowledge synthesis
Conclusions:Systematic reviews bring together evidence from multiple studies in a rigorous fashion for a single intervention or group of interventions. Systematic reviews, as they have developed within healthcare, often focus on single or select interventions and direct pairwise comparisons; therefore, end‐users may need to read several individual SRs to inform decision making. Overviews of reviews compile information from multiple SRs relevant to a single health problem. Overviews provide the end‐user with a quick overview of the available evidence; however, overviews are dependent on the methods and decisions employe...
Source: Evidence-Based Child Health: A Cochrane Review Journal - June 16, 2014 Category: Pediatrics Authors: Lisa Hartling, Ben Vandermeer, Ricardo M Fernandes Tags: Reviews Source Type: research

Cochrane in context: Maternal dietary antigen avoidance during pregnancy or lactation, or both, for preventing or treating atopic disease in the child
Abstract Cochrane Review: Maternal dietary antigen avoidance during pregnancy or lactation, or both, for preventing or treating atopic disease in the child Kramer MS, Kakuma R. Maternal dietary antigen avoidance during pregnancy or lactation, or both, for preventing or treating atopic disease in the child. Cochrane Database of Systematic Reviews 2012, Issue 9. Art. No.: CD000133. DOI: 10.1002/14651858.CD000133.pub3. This companion piece to the review, “Maternal dietary antigen avoidance during pregnancy or lactation, or both, for preventing or treating atopic disease in the child,” contains the following pieces: The ...
Source: Evidence-Based Child Health: A Cochrane Review Journal - June 16, 2014 Category: Pediatrics Authors: Michael S. Kramer, Ritsuko Kakuma Tags: Commentary Source Type: research

Maternal dietary antigen avoidance during pregnancy or lactation, or both, for preventing or treating atopic disease in the child
Abstract BackgroundSome breastfed infants with atopic eczema benefit from elimination of cow milk, egg, or other antigens from their mother's diet. Maternal dietary antigens are also known to cross the placenta. ObjectivesTo assess the effects of prescribing an antigen avoidance diet during pregnancy or lactation, or both, on maternal and infant nutrition and on the prevention or treatment of atopic disease in the child. Search methodsWe searched the Cochrane Pregnancy and Childbirth Group's Trials Register (6 July 2012). Selection criteriaAll randomized or quasi‐randomized comparisons of maternal dietary antigen avoidan...
Source: Evidence-Based Child Health: A Cochrane Review Journal - June 16, 2014 Category: Pediatrics Authors: Michael S Kramer, Ritsuko Kakuma Tags: Intervention Reviewa Source Type: research

Cochrane in context: Honey for acute cough in children
Abstract Cochrane Review: Honey for acute cough in children Oduwole O, Meremikwu MM, Oyo‐Ita A, Udoh EE. Honey for acute cough in children. Cochrane Database of Systematic Reviews 2012, Issue 3. Art. No.: CD007094. DOI: 10.1002/14651858.CD007094.pub3. This companion piece to the review, “Honey for acute cough in children,“ contains the following pieces: The abstract of the review A commentary from one or more of the review authors, explaining why the review team felt the review was an important one to produce A review of clinical practice guidelines from the American Academy of Pediatrics and the Canadian Paedi...
Source: Evidence-Based Child Health: A Cochrane Review Journal - June 16, 2014 Category: Pediatrics Authors: Olabisi Oduwole, Martin M. Meremikwu, Angela Oyo‐Ita, Ekong E. Udoh Tags: Commentary Source Type: research

Effect of timing of umbilical cord clamping of term infants on maternal and neonatal outcomes
Abstract BackgroundPolicies for timing of cord clamping vary, with early cord clamping generally carried out in the first 60 seconds after birth, whereas later cord clamping usually involves clamping the umbilical cord more than one minute after the birth or when cord pulsation has ceased. The benefits and potential harms of each policy are debated. ObjectivesTo determine the effects of early cord clamping compared with late cord clamping after birth on maternal and neonatal outcomes Search methodsWe searched the Cochrane Pregnancy and Childbirth Group's Trials Register (13 February 2013). Selection criteriaRandomised cont...
Source: Evidence-Based Child Health: A Cochrane Review Journal - June 16, 2014 Category: Pediatrics Authors: Susan J McDonald, Philippa Middleton, Therese Dowswell, Peter S Morris Tags: Intervention Review Source Type: research