Evidence-Based Child Health: A Cochrane Review Journal 
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Evidence-Based Child Health: A Cochrane Review Journal,Volume 9, Issue 4, Page 1047-1051, December 2014. (Source: Evidence-Based Child Health: A Cochrane Review Journal)
Source: Evidence-Based Child Health: A Cochrane Review Journal - December 15, 2014 Category: Pediatrics Source Type: research
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Evidence-Based Child Health: A Cochrane Review Journal,Volume 9, Issue 4, Page 827-828, December 2014. (Source: Evidence-Based Child Health: A Cochrane Review Journal)
Source: Evidence-Based Child Health: A Cochrane Review Journal - December 15, 2014 Category: Pediatrics Source Type: research
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Evidence-Based Child Health: A Cochrane Review Journal,Volume 9, Issue 4, Page 751-752, December 2014. (Source: Evidence-Based Child Health: A Cochrane Review Journal)
Source: Evidence-Based Child Health: A Cochrane Review Journal - December 15, 2014 Category: Pediatrics Source Type: research
A meta‐epidemiological study to examine the association between bias and treatment effects in neonatal trials
Conclusions:This observational study of a sample of neonatal trials showed that most were at high risk of bias, indicating that there is room for improvement in the design, conduct and reporting of neonatal trials to ensure valid results for the most clinically important outcomes. We did not find an association between most risk of bias domains and effect estimates; however, we found that randomized controlled trials at high risk for selective outcome reporting were associated with overestimates of treatment benefits. These results need to be confirmed in larger samples. (Source: Evidence-Based Child Health: A Cochrane Review Journal)
Source: Evidence-Based Child Health: A Cochrane Review Journal - December 15, 2014 Category: Pediatrics Authors: Liza Bialy, Ben Vandermeer, Thierry Lacaze‐Masmonteil, Donna M. Dryden, Lisa Hartling Tags: Overview of Reviews Source Type: research
Cochrane in context: Inhaled corticosteroids in children with persistent asthma: effects on growth and dose–response effects on growth
Abstract
Cochrane Review: Inhaled corticosteroids in children with persistent asthma: effects on growth Zhang L, Prietsch SOM, Ducharme FM. Inhaled corticosteroids in children with persistent asthma: effects on growth. Cochrane Database of Systematic Reviews 2014, Issue 7. Art. No.: CD009471. DOI: 10.1002/14651858.CD009471.pub2
Cochrane Review: Inhaled corticosteroids in children with persistent asthma: dose‐response effects on growth Pruteanu AI, Chauhan BF, Zhang L, Prietsch SOM, Ducharme FM. Inhaled corticosteroids in children with persistent asthma: dose–response effects on growth. Cochrane Database of Systematic R...
Source: Evidence-Based Child Health: A Cochrane Review Journal - December 15, 2014 Category: Pediatrics Authors: Linjie Zhang, Aniela I. Pruteanu, Sílvio O. M. Prietsch, Bhupendrasinh F. Chauhan, Francine M. Ducharme Tags: Commentary Source Type: research
Inhaled corticosteroids in children with persistent asthma: dose‐response effects on growth
ConclusionsWe report an evidence‐based ICS dose–dependent reduction in growth velocity in prepubescent school‐aged children with mild to moderate persistent asthma. The choice of ICS molecule (mometasone, ciclesonide or fluticasone) was not found to affect the level of growth velocity response over a year. The effect of corticosteroids on growth was not consistently reported: among 22 eligible trials, only four comparisons reported the effects of corticosteroids on growth over one year. In view of parents' and clinicians' concerns, lack of or incomplete reporting of growth is a matter of concern given the importance ...
Source: Evidence-Based Child Health: A Cochrane Review Journal - December 15, 2014 Category: Pediatrics Authors: Aniela I Pruteanu, Bhupendrasinh F Chauhan, Linjie Zhang, Sílvio OM Prietsch, Francine M Ducharme Tags: Intervention Review Source Type: research
Inhaled corticosteroids in children with persistent asthma: effects on growth
Abstract
BackgroundTreatment guidelines for asthma recommend inhaled corticosteroids (ICS) as first‐line therapy for children with persistent asthma. Although ICS treatment is generally considered safe in children, the potential systemic adverse effects related to regular use of these drugs have been and continue to be a matter of concern, especially the effects on linear growth.
ObjectivesTo assess the impact of ICS on the linear growth of children with persistent asthma and to explore potential effect modifiers such as characteristics of available treatments (molecule, dose, length of exposure, inhalation device) and o...
Source: Evidence-Based Child Health: A Cochrane Review Journal - December 15, 2014 Category: Pediatrics Authors: Linjie Zhang, Sílvio OM Prietsch, Francine M Ducharme Tags: Intervention Review Source Type: research
Cochrane in context: Interventions for treating femoral shaft fractures in children and adolescents
Abstract
Cochrane Review: Interventions for treating femoral shaft fractures in children and adolescents Madhuri V, Dutt V, Gahukamble AD, Tharyan P. Interventions for treating femoral shaft fractures in children and adolescents. Cochrane Database of Systematic Reviews 2014, Issue 7. Art. No.: CD009076. DOI: 10.1002/14651858.CD009076.pub2.
This companion piece to the review, “Interventions for treating femoral shaft fractures in children and adolescents,” contains the following pieces:
The abstract of the review
A commentary from one or more of the review authors, explaining why the review team felt the review was ...
Source: Evidence-Based Child Health: A Cochrane Review Journal - December 15, 2014 Category: Pediatrics Authors: Vrisha Madhuri, Abhay Gahukamble Tags: Commentary Source Type: research
Interventions for treating femoral shaft fractures in children and adolescents
ConclusionsThis review found insufficient evidence to determine if long‐term function differs between surgical and conservative treatment of thigh bone fractures in children aged 4 to 12 years. It found surgery resulted in lower rates of malunion but increased the risk of serious adverse events, such as infections. It found internal nailing may speed up recovery.The review found there was insufficient evidence from comparisons of different methods of non‐surgical treatment to clearly show that any type of non‐surgical treatment is better than any other. The same conclusion applies to comparisons of different methods ...
Source: Evidence-Based Child Health: A Cochrane Review Journal - December 15, 2014 Category: Pediatrics Authors: Vrisha Madhuri, Vivek Dutt, Abhay D Gahukamble, Prathap Tharyan Tags: Intervention Review Source Type: research
Formoterol or salmeterol for asthma—should they be used as monotherapy?
Abstract
Eco‐paediatrics is an occasional feature in Evidence‐Based Child Health: A Cochrane Review Journal. Our goal is to contribute to the worldwide discussion on reducing waste in health care. In each instalment, we will select a recent Cochrane review highlighting a practice, still in use, which the available evidence tells us should be discontinued. (Source: Evidence-Based Child Health: A Cochrane Review Journal)
Source: Evidence-Based Child Health: A Cochrane Review Journal - December 15, 2014 Category: Pediatrics Authors: Mike Steiner Tags: Editorial Source Type: research
Pros and cons …
(Source: Evidence-Based Child Health: A Cochrane Review Journal)
Source: Evidence-Based Child Health: A Cochrane Review Journal - December 15, 2014 Category: Pediatrics Authors: Michael B.H. Smith Tags: Editorial Source Type: research
A meta ‐epidemiological study to examine the association between bias and treatment effects in neonatal trials
Conclusions:This observational study of a sample of neonatal trials showed that most were at high risk of bias, indicating that there is room for improvement in the design, conduct and reporting of neonatal trials to ensure valid results for the most clinically important outcomes. We did not find an association between most risk of bias domains and effect estimates; however, we found that randomized controlled trials at high risk for selective outcome reporting were associated with overestimates of treatment benefits. These results need to be confirmed in larger samples. (Source: Evidence-Based Child Health: A Cochrane Review Journal)
Source: Evidence-Based Child Health: A Cochrane Review Journal - December 14, 2014 Category: Pediatrics Authors: Liza Bialy, Ben Vandermeer, Thierry Lacaze ‐Masmonteil, Donna M. Dryden, Lisa Hartling Tags: Overview of Reviews Source Type: research
Inhaled corticosteroids in children with persistent asthma: dose ‐response effects on growth
ConclusionsWe report an evidence‐based ICS dose–dependent reduction in growth velocity in prepubescent school‐aged children with mild to moderate persistent asthma. The choice of ICS molecule (mometasone, ciclesonide or fluticasone) was not found to affect the level of growth velocity response over a year. The effect of corticosteroids on growth was not consistently reported: among 22 eligible trials, only four comparisons reported the effects of corticosteroids on growth over one year. In view of parents' and clinicians' concerns, lack of or incomplete reporting of growth is a matter of concern given the importance ...
Source: Evidence-Based Child Health: A Cochrane Review Journal - December 14, 2014 Category: Pediatrics Authors: Aniela I Pruteanu, Bhupendrasinh F Chauhan, Linjie Zhang, S ílvio OM Prietsch, Francine M Ducharme Tags: Intervention Review Source Type: research
Formoterol or salmeterol for asthma —should they be used as monotherapy?
Abstract
Eco‐paediatrics is an occasional feature in Evidence‐Based Child Health: A Cochrane Review Journal. Our goal is to contribute to the worldwide discussion on reducing waste in health care. In each instalment, we will select a recent Cochrane review highlighting a practice, still in use, which the available evidence tells us should be discontinued. (Source: Evidence-Based Child Health: A Cochrane Review Journal)
Source: Evidence-Based Child Health: A Cochrane Review Journal - December 14, 2014 Category: Pediatrics Authors: Mike Steiner Tags: Editorial Source Type: research
Issue Information
(Source: Evidence-Based Child Health: A Cochrane Review Journal)
Source: Evidence-Based Child Health: A Cochrane Review Journal - December 1, 2014 Category: Pediatrics Tags: Issue Information Source Type: research
