Enamel and dental anomalies in latent ‐transforming growth factor beta‐binding protein 3 mutant mice
Latent‐transforming growth factor beta‐binding protein 3 (LTBP‐3) is important for craniofacial morphogenesis and hard tissue mineralization, as it is essential for activation of transforming growth factor‐β (TGF‐β). To investigate the role of LTBP‐3 in tooth formation we performed micro‐computed tomography (micro‐CT), histology, and scanning electron microscopy analyses of adult Ltbp3‐/‐ mice. The Ltbp3‐/‐ mutants presented with unique craniofacial malformations and reductions in enamel formation that began at the matrix formation stage. Organization of maturation‐stage ameloblasts was severely...
Source: European Journal of Oral Sciences - January 12, 2017 Category: Dentistry Authors: Supawich Morkmued, Joseph Hemmerle, Eric Mathieu, Virginie Laugel ‐Haushalter, Branka Dabovic, Daniel B. Rifkin, Pascal Dollé, Karen Niederreither, Agnès Bloch‐Zupan Tags: Original Article Source Type: research
Effect of mold diameter on the depth of cure of a resin ‐based composite material
The purpose of this study was to examine the effect of mold diameter on depth of cure of a resin‐based composite material for varying amounts of irradiation. A resin‐based composite was light‐cured for 10–80 s in stainless‐steel molds of either 6 mm or 4 mm in diameter and then dark‐stored for 24 h. Specimens were then scraped back and the length of the cured specimens was measured to provide depth of cure (DSB). Radiant exposure to each of the mold diameters was determined by measuring the power. The DSB values using the 4‐mm molds were lower than those of the 6‐mm molds. The average difference between the...
Source: European Journal of Oral Sciences - January 8, 2017 Category: Dentistry Authors: Robert L. Erickson, Wayne W. Barkmeier Tags: Original Article Source Type: research
A novel technique of delivering viral vectors to trigeminal ganglia in rats
The objective of this study was to develop a viable and reliable technique of delivering viral vectors to rat trigeminal ganglia. Adult Sprague‐Dawley rats (200–300 g) were used, and lentiviral vectors containing enhanced green fluorescence protein and calcitonin gene‐related peptide short hairpin RNA (shRNA) were generated. Following general anesthesia, viral vectors were delivered to rat trigeminal ganglia using the technique described in this study. Both X‐ray and micro‐computed tomography (micro‐CT) were employed to verify the position of the needles when injecting the vectors. In vivo fluorescence imaging ...
Source: European Journal of Oral Sciences - November 30, 2016 Category: Dentistry Authors: Hu Long, Lina Liao, Yang Zhou, Di Shan, Meiya Gao, Renhuan Huang, Xin Yang, Wenli Lai Tags: Original Article Source Type: research
Oral health improvements in Switzerland over 20 years
In conclusion, over the two decades of the study, the oral health of the Swiss population substantially improved. Although sociodemographic differences persisted, they decreased considerably in terms of the number of missing teeth and percentage of the population with a functional dentition. (Source: European Journal of Oral Sciences)
Source: European Journal of Oral Sciences - November 30, 2016 Category: Dentistry Authors: Cornelia Schneider, Elisabeth Zemp, Nicola U. Zitzmann Tags: Original Article Source Type: research
Oral health of children with attention deficit hyperactivity disorder
This study assessed and compared oral health and oral‐health behaviours among children with and without attention deficit hyperactivity disorder (ADHD). The study included 31 children, 12–18 yr of age, with ADHD and 31 age‐ and gender‐matched children without ADHD. Clinical data were recorded by a trained and calibrated examiner for caries, traumatic dental injuries, periodontal health, tooth wear, and salivary function. A questionnaire was also given to parents or caregivers about the oral health habits and behaviours of these children. Data were compared using Mann–Whitney U‐tests and chi‐square tests. No s...
Source: European Journal of Oral Sciences - November 30, 2016 Category: Dentistry Authors: Yvonne C. Y. Chau, Kelly Y. C. Lai, Colman P. J. McGrath, Cynthia K. Y. Yiu Tags: Original Article Source Type: research
Human salivary gland cells express bradykinin receptors that modulate the expression of proinflammatory cytokines
Bradykinin is an important peptide modulator that affects the function of neurons and immune cells. However, there is no evidence of the bradykinin receptors and their functions in human salivary glands. Here we have identified and characterized bradykinin receptors on human submandibular gland cells. Both bradykinin B1 and B2 receptors are expressed on human submandibular gland cells, A253 cells, and HSG cells. Bradykinin increased the intracellular Ca2+ concentration ([Ca2+]i) in a concentration‐dependent manner. Interestingly, a specific agonist of the B1 receptor did not have any effect on [Ca2+]i in HSG cells, where...
Source: European Journal of Oral Sciences - November 30, 2016 Category: Dentistry Authors: Keimin Lee, Yoon ‐Jung Kim, La‐Mee Choi, Seulki Choi, Hyun Nam, Hui‐Yeon Ko, Gehoon Chung, Jong‐Ho Lee, Su‐Hyun Jo, Gene Lee, Se‐Young Choi, Kyungpyo Park Tags: Original Article Source Type: research
Effect of a brief episode of experimental muscle pain on jaw movement and jaw ‐muscle activity during chewing
The aims of this study were to determine whether: (i) the jaw motor system develops a new pattern of jaw movement and/or jaw‐muscle activity after resolution of an acute episode of jaw‐muscle pain; and (ii) if jaw‐muscle activity and jaw‐movement features change progressively with repetition of a chewing sequence. Jaw movement and jaw muscle (masseter, anterior temporalis, and digastric) activity were recorded during free and rate‐standardized chewing in eight asymptomatic participants (pain infusion group), before and at three time blocks up to 45 min after a single 0.2‐ml bolus infusion of 5% hypertonic salin...
Source: European Journal of Oral Sciences - November 30, 2016 Category: Dentistry Authors: Kyoko Inamoto, Greg M. Murray, Terry Whittle Tags: Original Article Source Type: research
Intrafibrillar mineralization of polyacrylic acid ‐bound collagen fibrils using a two‐dimensional collagen model and Portland cement‐based resins
The biomimetic remineralization of apatite‐depleted dentin is a potential method for enhancing the durability of resin–dentin bonding. To advance this strategy from its initial proof‐of‐concept design, we sought to investigate the characteristics of polyacrylic acid (PAA) adsorption to desorption from type I collagen and to test the mineralization ability of PAA‐bound collagen. Portland cement and β‐tricalcium phosphate (β‐TCP) were homogenized with a hydrophilic resin blend to produce experimental resins. The collagen fibrils reconstituted on nickel (Ni) grids were mineralized using different methods: (i) ...
Source: European Journal of Oral Sciences - November 30, 2016 Category: Dentistry Authors: Shiyu Wu, Lisha Gu, Zihua Huang, Qiurong Sun, Huimin Chen, Junqi Ling, Sui Mai Tags: Original Article Source Type: research
Effect of FK ‐506 (tacrolimus) therapy on bone healing of titanium implants: a histometric and biomechanical study in mice
Immunosuppressive agents have been recognized as a factor affecting bone metabolism. The aim of the present study was to evaluate the influence of FK‐506 administration on the healing of bone around titanium implants. Thirty‐two male mice were randomly allocated to two groups: the FK‐506 group (n = 16 mice), which received subcutaneous administration of FK‐506 (1 mg kg−1 d−1); and the control group (n = 16 mice), which received saline solution by the same route of administration. After 2 wk, one titanium implant with sandblasted/acid‐etched surface was placed in the femur. The therapy continued until the mice...
Source: European Journal of Oral Sciences - November 30, 2016 Category: Dentistry Authors: Xiaofei Zheng, Anchun Mo, Yuan Wang, Yuchen Guo, Yunshu Wu, Quan Yuan Tags: Original Article Source Type: research
Glutaraldehyde collagen cross ‐linking stabilizes resin–dentin interfaces and reduces bond degradation
This study evaluated the stability of resin–dentin interfaces treated with glutaraldehyde‐containing agents, and assessed collagen degradation in dentin matrices treated with Gluma. Microtensile bond strength (μTBS) was evaluated 24 h and 6 months after treatment with three desensitizers (Gluma Desensitizer, Gluma Desensitizer Power Gel, and MicroPrime G) and two etch‐and‐rinse adhesives (Comfort Bond & Desensitizer and iBond TE). Demineralized beams of human dentin were treated with water or Gluma, and the degradation of collagen in these beams was assessed by quantification of the dry mass loss and of the am...
Source: European Journal of Oral Sciences - November 16, 2016 Category: Dentistry Authors: Joshua Lee, Camila Sabatini Tags: Original Article Source Type: research
Promotion of resin bonding to dental zirconia ceramic using plasma deposition of tetramethylsilane and benzene
The aim of this study was to investigate the effects of plasma‐enhanced deposition of an organosilane and benzene on resin bonding to a dental zirconia ceramic. A total of 70 zirconia specimens, which were polished before sintering, were randomly divided into five groups according to surface treatments before applying a dental adhesive (each group, n = 14): group 1, no previous treatment (control); group 2, plasma deposition with tetramethylsilane (TMS); group 3, plasma deposition with benzene; group 4, sequential plasma deposition with TMS and benzene; and group 5, a zirconia primer (Z‐Prime Plus). A dental adhesive (...
Source: European Journal of Oral Sciences - November 15, 2016 Category: Dentistry Authors: Geum ‐Jun Han, Jae‐Hoon Kim, Byeong‐Hoon Cho, Kyu‐Hwan Oh, Je‐Jun Jeong Tags: Original Article Source Type: research
Instructions to Contributors
(Source: European Journal of Oral Sciences)
Source: European Journal of Oral Sciences - November 11, 2016 Category: Dentistry Tags: Instructions to contributors Source Type: research
Volume content for 2016
(Source: European Journal of Oral Sciences)
Source: European Journal of Oral Sciences - November 11, 2016 Category: Dentistry Tags: Volume Contents Source Type: research
Reviewers 2016
(Source: European Journal of Oral Sciences)
Source: European Journal of Oral Sciences - November 11, 2016 Category: Dentistry Tags: Reviewers 2016 Source Type: research
Instructions to Contributors
(Source: European Journal of Oral Sciences)
Source: European Journal of Oral Sciences - October 2, 2016 Category: Dentistry Tags: Instructions to contributors Source Type: research
