Impaired polymorphonuclear neutrophils in the oral cavity of edentulous individuals
This study demonstrates that despite having functional cPMNs, edentulous subjects have low oPMN numbers that are functionally impaired. (Source: European Journal of Oral Sciences)
Source: European Journal of Oral Sciences - August 19, 2017 Category: Dentistry Authors: Patrick Rijkschroeff, Bruno G. Loos, Elena A. Nicu Tags: Original Article Source Type: research
Self ‐perceived mouthfeel and physico‐chemical surface effects after chewing gums containing sorbitol and Magnolia bark extract
The European Food Safety Authority recognizes the contribution of sugar‐free chewing gum to oral health through increased salivation, clearance of food debris, and neutralization of biofilm pH. Magnolia bark extract is a gum additive shown to reduce the prevalence of bad‐breath bacteria but its effects on self‐perceived mouthfeel are unknown. This paper aims to relate the effects of sorbitol‐containing chewing gum, with and without Magnolia bark extract, on tooth‐surface hydrophobicity and salivary‐film composition with self‐perceived mouthfeel. In a crossover clinical trial, volunteers chewed sorbitol‐cont...
Source: European Journal of Oral Sciences - August 1, 2017 Category: Dentistry Authors: Stefan W. Wessel, Henny C. Mei, Anje M. Slomp, Betsy Belt ‐Gritter, Michael W.J. Dodds, Henk J. Busscher Tags: Original Article Source Type: research
Effect of a 12 ‐methacryloyloxy‐dodecyl‐pyridinium‐bromide–containing adhesive with different post types on the long‐term bond strength to dentin
This study assessed the effect of an MDPB‐containing adhesive on the long‐term bond strength of GF or PF posts to bovine dentine. Bovine endodontically treated roots were randomly divided into six groups, according to the post type and adhesive system used, as follows: GF serrated post + MDBP‐free adhesive; GF serrated post + MDPB‐containing adhesive; GF smooth post + MDBP‐free adhesive; GF smooth post + MDPB‐containing adhesive; PF post + MDBP‐free adhesive; PF post + MDPB‐containing adhesive. Specimens were stored in water for 6 months, thermocycled (500 cycles wk−1), and submitted to the pull‐out tes...
Source: European Journal of Oral Sciences - August 1, 2017 Category: Dentistry Authors: Nat ália S. Faria, Luana K. B. Moura, Luciana M. D. Macedo, Vivian Colucci, Walter Raucci‐Neto, Danielle C. Messias Tags: Original Article Source Type: research
Participation of extracellular signal ‐regulated kinases 1/2 in osteoblast and adipocyte differentiation of mesenchymal stem cells grown on titanium surfaces
Osteoblasts and adipocytes coexist in the implantation site and affect the process of titanium (Ti) osseointegration. As extracellular signal‐regulated kinases 1/2 (ERK1/2) are involved in osteogenesis and adipogenesis, the aim of our study was to investigate if the effects of Ti surface topography on osteoblast and adipocyte differentiation are modulated by ERK1/2. The experiments were conducted based on the effect of the ERK1/2 inhibitor, PD98059, on mesenchymal stem cells (MSCs) grown under osteogenic and adipogenic conditions on Ti with nanotopography (Ti‐Nano) or on machined Ti (Ti‐Machined). The results showed ...
Source: European Journal of Oral Sciences - August 1, 2017 Category: Dentistry Authors: Heitor F. Silva, Rodrigo P.F. Abuna, Helena B. Lopes, Marcelo S. Francischini, Paulo T. Oliveira, Adalberto L. Rosa, Marcio M. Beloti Tags: Original Article Source Type: research
Effect of resveratrol on c ‐fos expression of rat trigeminal spinal nucleus caudalis and C1 dorsal horn neurons following mustard oil‐induced acute inflammation
The dietary constituent, resveratrol, was recently identified as a transient receptor potential ankyrin 1 (TRPA1) antagonist, voltage‐dependent sodium ion (Na+) channel, and cyclooxygenase‐2 (COX‐2) inhibitor. The aim of the present study was to investigate whether pretreatment with resveratrol attenuates acute inflammation‐induced sensitization of nociceptive processing in rat spinal trigeminal nucleus caudalis (SpVc) and upper cervical (C1) dorsal horn neurons, via c‐fos immunoreactivity. Mustard oil (MO), a TRPA1 channel agonist, was injected into the whisker pads of rats to induce inflammation. Pretreatment w...
Source: European Journal of Oral Sciences - August 1, 2017 Category: Dentistry Authors: Yasuhiro Matsumoto, Kyouhei Komatsu, Yoshihito Shimazu, Shiori Takehana, Yumiko Syouji, Ayumu Kobayashi, Mamoru Takeda Tags: Original Article Source Type: research
Orthodontically induced osteocyte apoptosis under different force magnitudes in rats: an immunohistochemical study
We investigated the effect of different force magnitudes on osteocyte apoptosis in a model of orthodontic tooth movement. Forty‐nine male Sprague Dawley rats (7–9 wk of age) were divided into light‐ and heavy‐force groups (n = 21 each group) and a control group (n = 7). A coil spring delivered pressure (either 10–15 g or 20–25 g) to the left maxillary first molar. The rats were sacrificed 1, 3, or 5 d after placement of the appliance. Sections of the maxillary first molars were immunostained for caspase‐3. Upon force application, the number of apoptotic osteocytes significantly increased in the pressu...
Source: European Journal of Oral Sciences - August 1, 2017 Category: Dentistry Authors: Hassan E. Kassem, Iman M. Talaat, Afaf El ‐Sawa, Hanan Ismail, Abbas Zaher Tags: Original Article Source Type: research
Effect of maleic acid on the bond strength of fibre posts to root dentine
The aim of this study was to evaluate the effect of maleic acid (MA) on both the bond strength of fibre post to root dentine and smear layer removal after post space preparation. Sixty, single‐canal premolars were endodontically treated and randomly assigned to four groups: group 1 [0.9% saline solution (control]); group 2 [2.5% sodium hypochlorite (NaOCl)]; group 3 [17% ethylenediaminetetraacetic acid (EDTA) followed by 2.5% NaOCl]; and group 4 (7% MA followed by 2.5% NaOCl). Self‐adhesive resin cement was used to test the adhesion of a glass‐fibre post to the root dentine through a micropush‐out test. Scanning el...
Source: European Journal of Oral Sciences - August 1, 2017 Category: Dentistry Authors: Fan Fan, Muhammad Ibrahim, Panpan Dai, Yixin Mao, Bing He, Gang Wu, Jianfeng Ma, Shengbin Huang Tags: Original Article Source Type: research
Assessment of the involvement of the macrophage migration inhibitory factor –glucocorticoid regulatory dyad in the expression of matrix metalloproteinase‐2 during periodontitis
This study investigated the role of the MIF–GC regulatory dyad in the expression and release of matrix metalloproteinase‐2 (MMP‐2) during periodontitis, in vivo and in vitro. In a Mif‐knockout (KO) mouse model of ligature‐induced periodontitis, gingival tissues and blood were collected and analysed for levels of interleukin‐6 (IL‐6), MIF, MMP‐2, and corticosterone. In addition, human gingival fibroblasts (HGFs) were tested for production of IL‐6 and MMP‐2 after stimulation with hydrocortisone (HC), MIF, tumour necrosis factor‐alpha (TNF‐α), or Fusobacterium nucleatum, a pathogen known to elicit i...
Source: European Journal of Oral Sciences - August 1, 2017 Category: Dentistry Authors: Josefine Hirschfeld, Mohammed Howait, Alexandru Movila, Marijo Par čina, Isabelle Bekeredjian‐Ding, James Deschner, Søren Jepsen, Toshihisa Kawai Tags: Original Article Source Type: research
Influence of application method on surface free ‐energy and bond strength of universal adhesive systems to enamel
The aim of the present study was to determine the influence of different adhesive application methods and etching modes on enamel bond effectiveness of universal adhesives using shear bond strength (SBS) testing and surface free‐energy (SFE) measurements. The adhesives Scotchbond Universal, All‐Bond Universal, Adhese Universal, and G‐Premio Bond were used. Prepared bovine enamel specimens were divided into four groups, based on type of adhesive, and subjected to the following surface treatments: (i) total‐etch mode with active application; (ii) total‐etch mode with inactive application; (iii) self‐etch mode wit...
Source: European Journal of Oral Sciences - July 27, 2017 Category: Dentistry Authors: Arisa Imai, Toshiki Takamizawa, Keiichi Sai, Akimasa Tsujimoto, Kie Nojiri, Hajime Endo, Wayne W. Barkmeier, Mark A. Latta, Masashi Miyazaki Tags: Original Article Source Type: research
Author Guidelines
(Source: European Journal of Oral Sciences)
Source: European Journal of Oral Sciences - July 5, 2017 Category: Dentistry Tags: Instructions to contributors Source Type: research
Antibiotic ‐prescribing habits among Norwegian dentists: a survey over 25 years (1990–2015)
Bacterial antibiotic resistance is a steadily growing global problem, which today is compared with issues such as global warming, ozone depletion, and extinction of species. Consequently, calls come from global, Pan‐European, and national authorities to gain insight into, limit, and stringently qualify the use of antibiotics in human and veterinary medicine, as well as in food production. Dentists are not considered to be frequent prescribers of antibiotics. However, few studies have identified how much, and in which situations, dentists prescribe such drugs. The aims of the present study were to survey Norwegian dentist...
Source: European Journal of Oral Sciences - June 27, 2017 Category: Dentistry Authors: Hans R. Preus, Karen W. Fredriksen, Andrea E. Vogsland, Leiv Sandvik, Jostein I. Grytten Tags: Original Article Source Type: research
Oral problems and quality of life of preschool children: self ‐reports of children and perception of parents/caregivers
The purpose of this study was to evaluate the association between oral health problems and oral health‐related quality of life (OHRQoL) of preschool children according to both self‐reports and the reports of parents/caregivers. A school‐based, cross‐sectional study was conducted with 769 preschool children and their parents/caregivers. The OHRQoL was evaluated using the Scale of Oral Health Outcomes for Five‐Year‐Old Children (SOHO‐5). Based on logistic regression for complex samples, the following variables were found to be associated with poorer OHRQoL in the parent/caregiver version: toothache (OR = 6.77; ...
Source: European Journal of Oral Sciences - June 27, 2017 Category: Dentistry Authors: Matheus F. Perazzo, Monalisa C. Gomes, Érick T. Neves, Carolina C. Martins, Saul M. Paiva, Edja M. M. de B. Costa, Ana F. Granville‐Garcia Tags: Original Article Source Type: research
Clinical association between chronic periodontitis and the leukocyte extravasation inhibitors developmental endothelial locus ‐1 and pentraxin‐3
This clinical study aimed to determine whether periodontal disease is associated with expression of developmental endothelial locus‐1 (Del‐1) and pentraxin‐3 (PTX‐3), endogenous inhibitors of leukocyte extravasation in humans. Expression of DEL1, PTX3, interleukin‐17A (IL17A), and lymphocyte function‐associated antigen‐1 (LFA1) was determined, using RT‐PCR and melting curve analysis, in biopsies of gingival tissues from 95 patients: 42 with moderate periodontitis; 40 with severe periodontitis; and 13 healthy controls. Relative expression of DEL1 and PTX3 was statistically significantly weaker in patients wi...
Source: European Journal of Oral Sciences - June 23, 2017 Category: Dentistry Authors: Matthias Folwaczny, Evangelia Karnesi, Tamara Berger, Ekaterini Paschos Tags: Original Article Source Type: research
Effect of pH on dentin protease inactivation by carbodiimide
This study indicates that the pH of the EDC solution plays an important role in the stability of dentin protease inactivation. (Source: European Journal of Oral Sciences)
Source: European Journal of Oral Sciences - June 23, 2017 Category: Dentistry Authors: Roda Seseogullari ‐Dirihan, Mustafa M. Mutluay, Leo Tjäderhane, Lorenzo Breschi, David H. Pashley, Arzu Tezvergil‐Mutluay Tags: Original Article Source Type: research
Angiotensin 1 ‐7 inhibits angiotensin II‐stimulated head and neck cancer progression
Angiotensin II (Ang II) is the product of the proteolytic action of angiotensin‐converting enzyme (ACE) on the precursor peptide, angiotensin I (Ang I). In addition to its vasoactive properties, Ang II is able to stimulate angiogenesis and act as a mitogen, promoting cellular proliferation. Recently, evidence has emerged that Ang II is also able to promote tumour invasion, a key step in the metastatic cascade, although the mechanisms by which it does so remain largely obscure. Here we show that Ang II is able to promote the invasion and migration of head and neck squamous cell carcinoma (HNSCC) cells both in an autocrine...
Source: European Journal of Oral Sciences - June 1, 2017 Category: Dentistry Authors: E. E. Hinsley, C. E. Oliveira, S. Hunt, R. D. Coletta, D. W. Lambert Tags: Original Article Source Type: research
