Author Guidelines
(Source: European Journal of Oral Sciences)
Source: European Journal of Oral Sciences - March 5, 2017 Category: Dentistry Tags: Instructions to contributors Source Type: research

FRAX and mandibular sparse trabeculation as fracture predictors: a longitudinal study from 1980 to 2002
The fracture assessment tool (FRAX) is widely used for predicting fractures, but better methods are needed. The aim of this study was to determine whether visual assessments of mandibular trabecular bone could improve FRAX predictions. Three age‐cohorts of women were examined twice – 499 women in 1980/1981 and 412 women in 1992/1993; 397 participated in both examinations. Information on 10‐yr fracture events was available, and bone trabeculation was assessed in radiographs as ‘dense’, ‘mixed’, or ‘sparse’. Fracture assessment tool values, without bone mineral density (BMD), were calculated twice. Both spa...
Source: European Journal of Oral Sciences - March 5, 2017 Category: Dentistry Authors: Valter Sundh, Dominique Hange, Margareta Ahlqwist, Magnus Hakeberg, Lauren Lissner, Grethe Jonasson Tags: Original Article Source Type: research

In vitro efficacy of a novel potassium oxalate hydrogel for dentin hypersensitivity
A novel potassium oxalate‐based hydrogel is proposed for treating dentin hypersensitivity and this study evaluates its in vitro performance as a remineralizing, desensitizing agent. Etched disks of human dentin were treated for 10 or 20 min using the test hydrogel, to mimic a professional application with dental mouth guards. Dentin disks were evaluated in terms of permeability indexes in a fluid‐filled system, the surface morphology was assessed by scanning electron microscopy, and the structural properties were studied using X‐ray diffraction analysis. The potassium oxalate hydrogel significantly reduced dentin p...
Source: European Journal of Oral Sciences - January 31, 2017 Category: Dentistry Authors: Elena M. Varoni, Tommaso Zuccheri, Andrea Carletta, Barbara Palazzo, Andrea Cochis, Martino Colonna, Lia Rimondini Tags: Original Article Source Type: research

Effect of silane pretreatment on the immediate bonding of universal adhesives to computer ‐aided design/computer‐aided manufacturing lithium disilicate glass ceramics
The aim of this study was to investigate the effect of silane pretreatment on the universal adhesive bonding between lithium disilicate glass ceramic and composite resin. IPS e.max ceramic blocks etched with hydrofluoric acid were randomly assigned to one of eight groups treated with one of four universal adhesives (two silane‐free adhesives and two silane‐containing adhesives), each with or without silane pretreatment. Bonded specimens were stored in water for 24 h. The shear bond strength (SBS) of the ceramic‐resin interface was measured to evaluate bond strength, and the debonded interface after the SBS test was a...
Source: European Journal of Oral Sciences - January 31, 2017 Category: Dentistry Authors: Chenmin Yao, Liqun Zhou, Hongye Yang, Yake Wang, Hualing Sun, Jingmei Guo, Cui Huang Tags: Original Article Source Type: research

Evaluation of ISO 4049: water sorption and water solubility of resin cements
The aim of this study was to evaluate the water sorption and solubility test design of ISO 4049 for resin cements. Sorption and solubility of six dual‐curing resin cements [RelyX Unicem 2 Automix (RUN), Multilink Speed CEM (MLS), Panavia SA Plus (PSA), RelyX Ultimate (RUL), Multilink Automix (MLA), and Panavia V5 (PV5)] were analyzed by storage in distilled water after dual‐curing. In addition, sorption and solubility during thermal cycling were assessed with self‐cured and dual‐cured specimens. After water storage, all cements revealed sorption in the range of 30 μg mm−3 except for PV5, for which sorption was...
Source: European Journal of Oral Sciences - January 31, 2017 Category: Dentistry Authors: Johannes A. M üller, Nadja Rohr, Jens Fischer Tags: Original Article Source Type: research

Effect of a one ‐step self‐etch adhesive on endogenous dentin matrix metalloproteinases
Degradation of the hybrid layer created in dentin by dentin adhesives is caused by enzyme activities present within the dentin matrix that destroy unprotected collagen fibrils. The aim of the present study was to evaluate the effect of a one‐step self‐etch adhesive system on dentinal matrix metalloproteinases 2 and 4 (MMP‐2 and MMP‐9, respectively) using in situ zymography and an enzymatic activity assay. The null hypothesis tested was that there are no differences in the activities of dentinal MMPs before and after treatment with a one‐step adhesive system. The MMP‐2 and MMP‐9 activities in dentin treated wi...
Source: European Journal of Oral Sciences - January 31, 2017 Category: Dentistry Authors: Fabianni M. Apolonio, Annalisa Mazzoni, Valeria Angeloni, Polliana M. C. Scaffa, Spartaco Santi, Vicente de Paulo A. Saboia, Franklin R. Tay, David H. Pashley, Lorenzo Breschi Tags: Original Article Source Type: research

Involvement of the phosphoinositide 3 ‐kinase/Akt signaling pathway in bone morphogenetic protein 9‐stimulated osteogenic differentiation and stromal cell‐derived factor 1 production in human periodontal ligament fibroblasts
Recent studies have shown that bone morphogenetic protein 9 (BMP‐9) can induce osteogenic differentiation in human periodontal stem cells and human periodontal ligament fibroblasts (PDLFs). Bone morphogenetic protein 9 may be used in periodontal tissue regeneration because of its potent osteoinductive ability. Human periodontal ligament cells also have been demonstrated to produce stromal cell‐derived factor 1 (SDF‐1), which is important for stem‐cell homing and recruitment to injured sites. In the present study, we examined the involvement of the phosphoinositide 3‐kinase (PI3K)/Akt signaling axis in osteogenic ...
Source: European Journal of Oral Sciences - January 31, 2017 Category: Dentistry Authors: Kirara Furue, Kotaro Sena, Kenji Sakoda, Toshiaki Nakamura, Kazuyuki Noguchi Tags: Original Article Source Type: research

Lack of evidence for prognostic value of epidermal growth factor receptor intron ‐1 CA repeats for oral carcinomas
Epidermal growth factor receptor (EGFR) expression is altered in several malignancies, including oral squamous cell carcinoma. A CA‐repeat polymorphism in intron‐1 (CA‐SSR‐1) of the EGFR gene is reported to influence EGFR expression and is associated with features of various solid tumors and outcomes of cancer patients. In the present study we evaluated the influence of length and zygosity of CA‐SSR‐1 on the survival of patients with oral squamous cell carcinoma. The length and zygosity of CA‐SSR‐1 was obtained through microsatellite analysis in 91 patients with oral cancer, who were treated in the Departme...
Source: European Journal of Oral Sciences - January 31, 2017 Category: Dentistry Authors: Clarissa Precht, Marco Blessmann, Lan Kluwe, Theresa Scheld, Gerhard Sch ön, Anders Henningsen, Christina Pflug, Ralf Smeets, Max Heiland, Alexander Gröbe Tags: Original Article Source Type: research

Wear characteristics and inhibition of enamel demineralization by resin ‐based coating materials
In conclusion, clinical use of the resin‐based coating materials with ion‐releasing ability may prevent demineralization of exposed enamel adjacent to the coating during treatment. (Source: European Journal of Oral Sciences)
Source: European Journal of Oral Sciences - January 31, 2017 Category: Dentistry Authors: Naohiko Kawamura, Masahiro Iijima, Shuich Ito, William A. Brantley, Satish B. Alapati, Takeshi Muguruma, Kyotaro Kawaguchi, Takashi Saito, Itaru Mizoguchi Tags: Original Article Source Type: research

Proprioceptive mechanisms in occlusion ‐stimulated masseter hypercontraction
Neurons in the trigeminal mesencephalic nucleus (Vme) have an axon that branches peripherally to innervate the orofacial region and projects centrally to the trigeminal motor nucleus (Vmo). They function as the primary neurons conveying proprioceptive messages. The present study aimed to demonstrate the presence of a periodontal–Vme–Vmo circuit and to provide evidence for its involvement in an experimental unilateral anterior crossbite (UAC) model, which can induce osteoarthritis in the temporomandibular joint. Cholera toxin B subunit (CTb) was injected into the inferior alveolar nerve of rats to help identify the cent...
Source: European Journal of Oral Sciences - January 31, 2017 Category: Dentistry Authors: Xin Liu, Chunkui Zhang, Dongmei Wang, Hongyun Zhang, Xiaodong Liu, Jinlian Li, Meiqing Wang Tags: Original Article Source Type: research

Haplotype ‐based gene–gene interaction of bone morphogenetic protein 4 and interferon regulatory factor 6 in the etiology of non‐syndromic cleft lip with or without cleft palate in a Chilean population
Non‐syndromic cleft lip with or without cleft palate (NSCL/P) is the most common craniofacial birth defect in humans, the etiology of which can be dependent on the interactions of multiple genes. We previously reported haplotype associations for polymorphic variants of interferon regulatory factor 6 (IRF6), msh homeobox 1 (MSX1), bone morphogenetic protein 4 (BMP4), and transforming growth factor beta 3 (TGFB3) in Chile. Here, we analyzed the haplotype‐based gene–gene interaction for markers of these genes and NSCL/P risk in the Chilean population. We genotyped 15 single nucleoptide polymorphisms (SNPs) in 152 Chilea...
Source: European Journal of Oral Sciences - January 30, 2017 Category: Dentistry Authors: Rafael Blanco, Alicia Colombo, Rosa Pardo, Jos é Suazo Tags: Original Article Source Type: research

Parasympathectomy increases resting salivary secretion in normal and irradiated submandibular glands of rats
This study evaluated the effect of parasympathectomy on salivary secretion from normal and irradiated rat SMGs from 1 to 24 wk after denervation. Although stimulated salivary secretion was significantly lower in denervated SMGs compared with contralateral self‐controls, the resting salivary flow rates were markedly higher in the denervated SMGs at 1, 12, and 24 wk after denervation. The levels of muscarinic acetylcholine M1 and M3 receptors, as well as of aquaporin 5, were up‐regulated. Notably, although irradiated SMGs showed significantly lower resting and stimulated salivary secretion rates than non‐irradiated SMG...
Source: European Journal of Oral Sciences - January 13, 2017 Category: Dentistry Authors: Wei Qi, Xin Cong, Xue ‐Ming Zhang, Zong‐Ye Wang, Ning‐Yan Yang, Chong Ding, Xiao‐Feng Shan, Li‐Ling Wu, Guang‐Yan Yu Tags: Original Article Source Type: research

Author Guidelines
(Source: European Journal of Oral Sciences)
Source: European Journal of Oral Sciences - January 12, 2017 Category: Dentistry Tags: Instructions to contributors Source Type: research

Corrigendum
(Source: European Journal of Oral Sciences)
Source: European Journal of Oral Sciences - January 12, 2017 Category: Dentistry Tags: Corrigendum Source Type: research

Relationship between gustatory function and average number of taste buds per fungiform papilla measured by confocal laser scanning microscopy in humans
The aim of this study was to elucidate the relationship between the gustatory function and average number of taste buds per fungiform papilla (FP) in humans. Systemically healthy volunteers (n = 211), pre‐operative patients with chronic otitis media (n = 79), and postoperative patients, with or without a chorda tympani nerve (CTN) severed during middle ear surgery (n = 63), were included. Confocal laser scanning microscopy was employed to observe fungiform taste buds because it allows many FP to be observed non‐invasively in a short period of time. Taste buds in an average of 10 FP in the midlateral region of the...
Source: European Journal of Oral Sciences - January 12, 2017 Category: Dentistry Authors: Takehisa Saito, Tetsufumi Ito, Yumi Ito, Yasuhiro Manabe, Kazuo Sano Tags: Original Article Source Type: research