miR ‐140‐5p‐mediated regulation of the proliferation and differentiation of human dental pulp stem cells occurs through the lipopolysaccharide/toll‐like receptor 4 signaling pathway
Human dental pulp stem cells (DPSCs) are oral mesenchymal stem cells with potential to differentiate into various cell types. Recent studies of DPSCs have focused on microRNAs (miRNAs), a class of small noncoding RNAs that play crucial roles in regulating DPSC phenotypes. In the current study, the expression of miR‐140‐5p was significantly decreased during lipopolysaccharide (LPS)‐mediated differentiation of DPSCs in vitro. Overexpression of miR‐140‐5p enhanced proliferation of DPSCs and inhibited DPSC differentiation, whereas suppression of miR‐140‐5p produced the opposite effect. Moreover, the expression o...
Source: European Journal of Oral Sciences - November 13, 2017 Category: Dentistry Authors: De ‐gang Sun, Bing‐chang Xin, Di Wu, Lei Zhou, Hong‐bin Wu, Wen Gong, Jian Lv Tags: Original Article Source Type: research
Dental hygienist attendance and its covariates in an ageing Swedish cohort
Delegation of tasks between professional groups is important to make health‐care services accessible and effective for ageing people. Focussing on a Swedish 1942 birth cohort and guided by Andersen's Behavioral Model, this study assessed dental hygienist attendance from age 50 to age 70 and identified covariates at the population‐averaged and person‐specific levels. In 1992, a census of 50‐yr‐old subjects was invited to participate in a questionnaire survey. Of the 6,346 respondents, 3,585 completed follow‐ups in 1997, 2002, 2007, and 2012. Multiple logistic regression analysis was conducted using a marginal mo...
Source: European Journal of Oral Sciences - October 30, 2017 Category: Dentistry Authors: Anne N. Åstrøm, Gunnar Ekbäck, Sven Ordell, Stein A. Lie, Ferda Gulcan Tags: Original Article Source Type: research
In vitro studies of the antimicrobial effect of non ‐thermal plasma‐activated water as a novel mouthwash
The aim of this study was to evaluate the antimicrobial effects of non‐thermal plasma‐activated water (PAW) as a novel mouthwash in vitro. Three representative oral pathogens – Streptococcus mutans, Actinomyces viscosus and Porphyromonas gingivalis – were treated with PAW. The inactivation effect was evaluated using the colony‐forming unit (CFU) method, and the morphological and structural changes of a cell were observed by scanning electron microscopy and transmission electron microscopy (TEM). The physicochemical properties of PAW were analysed, and its influence on the leakage of intracellular proteins and DNA...
Source: European Journal of Oral Sciences - October 11, 2017 Category: Dentistry Authors: Yinglong Li, Jie Pan, Guopin Ye, Qian Zhang, Jing Wang, Jue Zhang, Jing Fang Tags: Original Article Source Type: research
Effect of non ‐thermal atmospheric plasma on the dentin‐surface topography and composition and on the bond strength of a universal adhesive
This study investigated the effect of application of non‐thermal atmospheric plasma (NTAP) on the topography and composition of the dentin surface, as well as the microtensile bond strength (μTBS) of a universal adhesive to NTAP‐treated dentin. Exposed flat dentin surfaces from human third molars were either treated with NTAP for 10 and 30 s or untreated (control). The dentin‐surface topography and chemical composition were characterized by atomic force microscopy (n = 3) and Raman confocal spectroscopy (n = 5), respectively. The μTBS (n = 8) of Scotchbond Universal to dentin was determined after storage for...
Source: European Journal of Oral Sciences - October 1, 2017 Category: Dentistry Authors: Ana P. Ayres, Jean J. Bonvent, Borys Mogilevych, Luis E. S. Soares, Airton A. Martin, Glaucia M. Ambrosano, F ábio D. Nascimento, Bart Van Meerbeek, Marcelo Giannini Tags: Original Article Source Type: research
Genetic study of non ‐syndromic tooth agenesis through the screening of paired box 9, msh homeobox 1, axin 2, and Wnt family member 10A genes: a case‐series
Non‐syndromic tooth agenesis (NSTA) is the most common developmental anomaly in humans. Several studies have been conducted on dental agenesis and numerous genes have been identified. However, the pathogenic mechanisms responsible for NSTA are not clearly understood. We studied a group of 28 patients with sporadic NSTA and nine patients with a family history of tooth agenesis. We focused on four genes – paired box 9 (PAX9), Wnt family member 10A (WNT10A), msh homeobox 1 (MSX1), and axin 2 (AXIN2) – using direct Sanger sequencing of the exons and intron–exon boundaries. The most prevalent variants identified in PAX9...
Source: European Journal of Oral Sciences - October 1, 2017 Category: Dentistry Authors: Marwa Haddaji Mastouri, Peter De Coster, Aicha Zaghabani, Frej Jammali, Nabiha Raouahi, Amina Ben Salem, Ali Saad, Paul Coucke, Dorra H'mida Ben Brahim Tags: Original Article Source Type: research
Effect of topical fluoride application on enamel after in ‐office bleaching, as evaluated using a novel hardness tester and a transverse microradiography method
This study evaluated the effect of topical fluoride application on enamel hardness after in‐office bleaching. Twelve human incisors were cut along the long axis, resulting in 24 halves used in four treatment groups (n = 6 in each group): (i) untreated group (C); (ii) in‐office bleaching material (B); (iii) treatment with surface reaction‐type prereacted glass‐ionomer varnish after in‐office bleaching (B+PRG); and (iv) treatment with acidulated phosphate fluoride solution after bleaching (B+F). All specimens were subjected to pH‐cycling for 4 wk. Knoop hardness was measured using a Cariotester. The decalcificati...
Source: European Journal of Oral Sciences - October 1, 2017 Category: Dentistry Authors: Mai Fukuyama, Chiharu Kawamoto, Pipop Saikaew, Yasuhiro Matsuda, Ricardo M. Carvalho, Denis Selimovic, Hidehiko Sano Tags: Original Article Source Type: research
Influence of glutamate ‐evoked pain and sustained elevated muscle activity on blood oxygenation in the human masseter muscle
This study aimed to investigate the effect of glutamate‐evoked masseter muscle pain on intramuscular oxygenation during rest and sustained elevated muscle activity (SEMA). Seventeen healthy individuals participated in two sessions in which they were injected with glutamate and saline in random order. Each session was divided into three, 10‐min periods. During the first (period 1) and the last (period 3) 10‐min periods, participants performed five intercalated 1‐min bouts of masseter SEMA with 1‐min periods of ‘rest’. At onset of the second 10‐min period, glutamate (0.5 ml, 1 M; Ajinomoto, Tokyo, Japan) or...
Source: European Journal of Oral Sciences - October 1, 2017 Category: Dentistry Authors: Shunichi Suzuki, Taro Arima, Yoshimasa Kitagawa, Peter Svensson, Eduardo Castrillon Tags: Original Article Source Type: research
Oridonin induces apoptosis in human oral cancer cells via phosphorylation of histone H2AX
In this study, we assessed the role of oridonin as an inducer of apoptosis in HSC‐3 and HSC‐4 human oral cancer cells. Our results showed that oridonin reduces the viability of human oral cancer cells and significantly increases the expression of γH2AX, a well‐known marker of DNA damage. 4′,6‐Diamidino‐2‐phenylindole (DAPI) staining and western blotting showed that oridonin causes nuclear condensation and fragmentation, and induces cleavage of poly(ADP‐ribose) polymerase (PARP). Moreover, oridonin‐induced γH2AX accumulation was partially abrogated by Z‐VAD, a pan‐caspase inhibitor. Taken together, o...
Source: European Journal of Oral Sciences - October 1, 2017 Category: Dentistry Authors: In ‐Hyoung Yang, Ji‐Ae Shin, Kyung‐Eun Lee, Junghyun Kim, Nam‐Pyo Cho, Sung‐Dae Cho Tags: Original Article Source Type: research
Efficacy of vitamins E and C for reversing the cytotoxic effects of nicotine and cotinine
Nicotine has adverse cellular and molecular effects on oral mucosa, bone, and teeth. Vitamin E (α‐tocopherol) and vitamin C (ascorbic acid) are biological antioxidants with positive effects on wound healing and bone formation. This in vitro study sought to assess the cytotoxic effects of different concentrations of nicotine and cotinine (a metabolite of nicotine) on MG‐63 osteoblast‐like cells and human gingival fibroblasts (HGFs) in the presence and absence of antioxidant vitamins E and C (separately and combined). Cell viability and proliferation were assessed using the methyl thiazol tetrazolium (MTT) assay. Cell...
Source: European Journal of Oral Sciences - October 1, 2017 Category: Dentistry Authors: Maryam Torshabi, Zeinab Rezaei Esfahrood, Mahshid Jamshidi, Abbas Mansuri Torshizi, Samira Sotoudeh Tags: Original Article Source Type: research
Interaction between calcitonin gene ‐related peptide‐immunoreactive neurons and satellite cells via P2Y12R in the trigeminal ganglion is involved in neuropathic tongue pain in rats
The P2Y12 receptor expressed in satellite cells of the trigeminal ganglion is thought to contribute to neuropathic pain. The functional interaction between neurons and satellite cells via P2Y12 receptors and phosphorylated extracellular signal‐regulated kinase 1/2 (pERK1/2) underlying neuropathic pain in the tongue was evaluated in this study. Expression of P2Y12 receptor was enhanced in pERK1/2‐immunoreactive cells encircling trigeminal ganglion neurons after lingual nerve crush. The administration to lingual nerve crush rats of a selective P2Y12 receptor antagonist, MRS2395, attenuated tongue hypersensitivity to mech...
Source: European Journal of Oral Sciences - October 1, 2017 Category: Dentistry Authors: Shiori Sugawara, Shinji Okada, Ayano Katagiri, Hiroto Saito, Tatsuro Suzuki, Hiroki Komiya, Kohei Kanno, Kinuyo Ohara, Toshimitsu Iinuma, Akira Toyofuku, Koichi Iwata Tags: Original Article Source Type: research
Non ‐stick properties of thin‐film coatings on dental‐restorative instruments
The non‐stick properties of thin‐film coatings on dental‐restorative instruments were investigated by static contact‐angle measurement using dental filler resin as well as by scanning electron microscopy of the amount of sticking dental restorative material. Furthermore, using a customized dipping measurement set‐up, non‐stick properties were evaluated by measuring force‐by‐time when the instrument was pulled out of restorative material. Minor improvements in non‐stick properties were obtained with commercial diamond‐like carbon and commercial polytetrafluoroethylene‐based coatings. Major improvements...
Source: European Journal of Oral Sciences - September 18, 2017 Category: Dentistry Authors: Jarmo Lepp äniemi, Sasha Hoshian, Kimmo Suomalainen, Toni Luoto, Ville Jokinen, Jari Koskinen Tags: Original Article Source Type: research
Do patients benefit from orthognathic surgery? A systematic review on the effects of elective orthognathic surgery on psychosocial functioning and patient satisfaction
The main purpose of this systematic review was to determine the current state of evidence regarding patient satisfaction with, and the impact of, orthognathic surgery on psychosocial functioning of patients 17 yr of age and older. A secondary aim was to determine whether individuals with psychiatric disorders and mental health conditions are more likely to be dissatisfied with the treatment outcome than those without. We systematically searched PubMed, PsycInfo, and Embase for relevant studies (up to 6 June 2016). After selection of articles we determined the Directness of Evidence (DoE) and Risk of Bias (RoB). We identifi...
Source: European Journal of Oral Sciences - September 11, 2017 Category: Dentistry Authors: Dyonne L. M. Broers, Geert J. M. G. Heijden, Frederik R. Rozema, Ad Jongh Tags: Review Article Source Type: research
Perceptions of dental treatment need in Australian ‐born and migrant populations
The objective of this study was to investigate differences in self‐perceived and dentist‐determined treatment need in Australian‐born and migrant residents of Australia. Participants in the National Survey of Adult Oral Health 2004–06 were categorized into six groups according to country of birth. Interview and examination data were used to analyze differences between self‐perceived and the ‘gold standard’ examiner‐determined treatment need, and to compare the accuracy of self‐reporting according to country of birth. Self‐reported treatment needs, defined as the need for a restoration and/or extraction,...
Source: European Journal of Oral Sciences - September 5, 2017 Category: Dentistry Authors: Mathew A. W. T. Lim, Leonard A. Crocombe, Loc G. Do Tags: Original Article Source Type: research
Author Guidelines
(Source: European Journal of Oral Sciences)
Source: European Journal of Oral Sciences - September 5, 2017 Category: Dentistry Tags: Instructions to contributors Source Type: research
Guided bone regeneration: materials and biological mechanisms revisited
Guided bone regeneration (GBR) is commonly used in combination with the installment of titanium implants. The application of a membrane to exclude non‐osteogenic tissues from interfering with bone regeneration is a key principle of GBR. Membrane materials possess a number of properties which are amenable to modification. A large number of membranes have been introduced for experimental and clinical verification. This prompts the need for an update on membrane properties and the biological outcomes, as well as a critical assessment of the biological mechanisms governing bone regeneration in defects covered by membranes. T...
Source: European Journal of Oral Sciences - August 19, 2017 Category: Dentistry Authors: Ibrahim Elgali, Omar Omar, Christer Dahlin, Peter Thomsen Tags: Review Source Type: research
