Response to growth hormone in patients with RNPC3 mutations
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - June 6, 2018 Category: Molecular Biology Authors: Gabriel Á Martos‐Moreno , Lourdes Travieso‐Suárez , Jesús Pozo‐Román , María T Muñoz‐Calvo , Julie A Chowen , Mikko J Frilander , Luis A Pérez‐Jurado , Federico G Hawkins , Jesús Argente Source Type: research

Dynamics of multiple resistance mechanisms in plasma DNA during EGFR ‐targeted therapies in non‐small cell lung cancer
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - May 30, 2018 Category: Molecular Biology Authors: Dana Wai Yi Tsui , Muhammed Murtaza , Alvin Seng Cheong Wong , Oscar M Rueda , Christopher G Smith , Dineika Chandrananda , Ross A Soo , Hong Liang Lim , Boon Cher Goh , Carlos Caldas , Tim Forshew , Davina Gale , Wei Liu , James Source Type: research

The AMPK agonist 5 ‐aminoimidazole‐4‐carboxamide ribonucleotide (AICAR), but not metformin, prevents inflammation‐associated cachectic muscle wasting
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - May 29, 2018 Category: Molecular Biology Authors: Derek T Hall , Takla Griss , Jennifer F Ma , Brenda Janice Sanchez , Jason Sadek , Anne Marie K Tremblay , Souad Mubaid , Amr Omer , Rebecca J Ford , Nathalie Bedard , Arnim Pause , Simon S Wing , Sergio Di Marco , Gregory R Stei Source Type: research

CLK2 blockade modulates alternative splicing compromising MYC ‐driven breast tumors
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - May 22, 2018 Category: Molecular Biology Authors: Fernando Salvador , Roger R Gomis Source Type: research

A novel CHCHD10 mutation implicates a Mia40 ‐dependent mitochondrial import deficit in ALS
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - May 22, 2018 Category: Molecular Biology Authors: Carina Lehmer , Martin H Schludi , Linnea Ransom , Johanna Greiling , Michaela Jungh änel , Nicole Exner , Henrick Riemenschneider , Julie van der Zee , Christine Van Broeckhoven , Patrick Weydt , Michael T Heneka , Dieter Edbauer Source Type: research

Anti ‐tumor efficacy of a novel CLK inhibitor via targeting RNA splicing and MYC‐dependent vulnerability
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - May 16, 2018 Category: Molecular Biology Authors: Kenichi Iwai , Masahiro Yaguchi , Kazuho Nishimura , Yukiko Yamamoto , Toshiya Tamura , Daisuke Nakata , Ryo Dairiki , Yoichi Kawakita , Ryo Mizojiri , Yoshiteru Ito , Moriteru Asano , Hironobu Maezaki , Yusuke Nakayama , Misato Source Type: research

mtDNA heteroplasmy level and copy number indicate disease burden in m.3243A > G mitochondrial disease
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - May 7, 2018 Category: Molecular Biology Authors: John P Grady , Sarah J Pickett , Yi Shiau Ng , Charlotte L Alston , Emma L Blakely , Steven A Hardy , Catherine L Feeney , Alexandra A Bright , Andrew M Schaefer , Gr áinne S Gorman , Richard JQ McNally , Robert W Taylor , Doug Source Type: research

Enhancement of red blood cell transfusion compatibility using CRISPR ‐mediated erythroblast gene editing
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - April 26, 2018 Category: Molecular Biology Authors: Joseph Hawksworth , Timothy J Satchwell , Marjolein Meinders , Deborah E Daniels , Fiona Regan , Nicole M Thornton , Marieangela C Wilson , Johannes GG Dobbe , Geert J Streekstra , Kongtana Trakarnsanga , Kate J Heesom , David J Anst Source Type: research

Measles 2018: a tale of two anniversaries
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - April 23, 2018 Category: Molecular Biology Authors: Philippe J Sansonetti Source Type: research

Cholesterol metabolism promotes B ‐cell positioning during immune pathogenesis of chronic obstructive pulmonary disease
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - April 19, 2018 Category: Molecular Biology Authors: Jie Jia , Thomas M Conlon , Rim SJ Sarker , Demet Ta şdemir , Natalia F Smirnova , Barkha Srivastava , Stijn E Verleden , Gizem Güneş , Xiao Wu , Cornelia Prehn , Jiaqi Gao , Katharina Heinzelmann , Jutta Lintelmann , Martin Source Type: research

Identification of circadian clock modulators from existing drugs
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - April 17, 2018 Category: Molecular Biology Authors: T Katherine Tamai , Yusuke Nakane , Wataru Ota , Akane Kobayashi , Masateru Ishiguro , Naoya Kadofusa , Keisuke Ikegami , Kazuhiro Yagita , Yasufumi Shigeyoshi , Masaki Sudo , Taeko Nishiwaki ‐Ohkawa , Ayato Sato , Takashi Yoshi Source Type: research

A novel combination treatment against melanoma with NRAS mutation and therapy resistance
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - April 16, 2018 Category: Molecular Biology Authors: Yanlin Yu Source Type: research

PATL2 is a key actor of oocyte maturation whose invalidation causes infertility in women and mice
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - April 16, 2018 Category: Molecular Biology Authors: Marie Christou ‐Kent , Zine‐Eddine Kherraf , Amir Amiri‐Yekta , Emilie Le Blévec , Thomas Karaouzène , Béatrice Conne , Jessica Escoffier , Said Assou , Audrey Guttin , Emeline Lambert , Guillaume Martinez , Magalie Boguenet Source Type: research

Myeloid cell deficiency of p38 γ/p38δ protects against candidiasis and regulates antifungal immunity
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - April 16, 2018 Category: Molecular Biology Authors: Dayanira Alsina ‐Beauchamp , Alejandra Escós , Pilar Fajardo , Diego González‐Romero , Ester Díaz‐Mora , Ana Risco , Miguel A Martín‐Serrano , Carlos del Fresno , Jorge Dominguez‐Andrés , Noelia Aparicio , Rafal Zur , Source Type: research

Co ‐targeting BET and MEK as salvage therapy for MAPK and checkpoint inhibitor‐resistant melanoma
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - April 11, 2018 Category: Molecular Biology Authors: Ileabett M Echevarr ía‐Vargas , Patricia I Reyes‐Uribe , Adam N Guterres , Xiangfan Yin , Andrew V Kossenkov , Qin Liu , Gao Zhang , Clemens Krepler , Chaoran Cheng , Zhi Wei , Rajasekharan Somasundaram , Giorgos Karakousis , Source Type: research