Systematic pharmacological screens uncover novel pathways involved in cerebral cavernous malformations
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - September 4, 2018 Category: Molecular Biology Authors: C écile Otten , Jessica Knox , Gwénola Boulday , Mathias Eymery , Marta Haniszewski , Martin Neuenschwander , Silke Radetzki , Ingo Vogt , Kristina Hähn , Coralie De Luca , Cécile Cardoso , Sabri Hamad , Carla Igual Gil , Pet Source Type: research

Targeting miR ‐223 in neutrophils enhances the clearance of Staphylococcus aureus in infected wounds
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - August 31, 2018 Category: Molecular Biology Authors: Maiko de Kerckhove , Katsuya Tanaka , Takahiro Umehara , Momoko Okamoto , Sotaro Kanematsu , Hiroko Hayashi , Hiroki Yano , Soushi Nishiura , Shiho Tooyama , Yutaka Matsubayashi , Toshimitsu Komatsu , Seongjoon Park , Yuka Okada , Source Type: research

Activation of the epithelial sodium channel (ENaC) leads to cytokine profile shift to pro ‐inflammatory in labor
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - August 28, 2018 Category: Molecular Biology Authors: Xiao Sun , Jing Hui Guo , Dan Zhang , Jun ‐jiang Chen , Wei Yin Lin , Yun Huang , Hui Chen , Wen Qing Huang , Yifeng Liu , Lai Ling Tsang , Mei Kuen Yu , Yiu Wa Chung , Xiaohua Jiang , Hefeng Huang , Hsiao Chang Chan , Y Source Type: research

Cancer cell adaptation to hypoxia involves a HIF ‐GPRC5A‐YAP axis
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - August 24, 2018 Category: Molecular Biology Authors: Alexander Greenhough , Clare Bagley , Kate J Heesom , David B Gurevich , David Gay , Mark Bond , Tracey J Collard , Chris Paraskeva , Paul Martin , Owen J Sansom , Karim Malik , Ann C Williams Source Type: research

Parkin is a disease modifier in the mutant SOD1 mouse model of ALS
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - August 20, 2018 Category: Molecular Biology Authors: Gloria M Palomo , Veronica Granatiero , Hibiki Kawamata , Csaba Konrad , Michelle Kim , Andrea J Arreguin , Dazhi Zhao , Teresa A Milner , Giovanni Manfredi Source Type: research

Dual reporter genetic mouse models of pancreatic cancer identify an epithelial ‐to‐mesenchymal transition‐independent metastasis program
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - August 17, 2018 Category: Molecular Biology Authors: Yang Chen , Valerie S LeBleu , Julienne L Carstens , Hikaru Sugimoto , Xiaofeng Zheng , Shruti Malasi , Dieter Saur , Raghu Kalluri Source Type: research

Comprehensive evaluation of coding region point mutations in microsatellite ‐unstable colorectal cancer
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - August 14, 2018 Category: Molecular Biology Authors: Johanna Kondelin , Kari Salokas , Lilli Saarinen , Kristian Ovaska , Heli Rauanheimo , Roosa ‐Maria Plaketti , Jiri Hamberg , Xiaonan Liu , Leena Yadav , Alexandra E Gylfe , Tatiana Cajuso , Ulrika A Hänninen , Kimmo Palin , Source Type: research

CEP55 is a determinant of cell fate during perturbed mitosis in breast cancer
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - August 14, 2018 Category: Molecular Biology Authors: Murugan Kalimutho , Debottam Sinha , Jessie Jeffery , Katia Nones , Sriganesh Srihari , Winnie C Fernando , Pascal HG Duijf , Claire Vennin , Prahlad Raninga , Devathri Nanayakkara , Deepak Mittal , Jodi M Saunus , Sunil R Lakhani Source Type: research

Comparative proteomics reveals a diagnostic signature for pulmonary head ‐and‐neck cancer metastasis
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - August 10, 2018 Category: Molecular Biology Authors: Hanibal Bohnenberger , Lars Kaderali , Philipp Str öbel , Diego Yepes , Uwe Plessmann , Neekesh V Dharia , Sha Yao , Carina Heydt , Sabine Merkelbach‐Bruse , Alexander Emmert , Jonatan Hoffmann , Julius Bodemeyer , Kirsten Reut Source Type: research

Enriched environment enhances β‐adrenergic signaling to prevent microglia inflammation by amyloid‐β
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - August 9, 2018 Category: Molecular Biology Authors: Huixin Xu , Molly M Rajsombath , Pia Weikop , Dennis J Selkoe Source Type: research

Should the 14 ‐day rule for embryo research become the 28‐day rule?
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - August 7, 2018 Category: Molecular Biology Authors: John B Appleby , Annelien L Bredenoord Source Type: research

EGFL7 enhances surface expression of integrin α5β1 to promote angiogenesis in malignant brain tumors
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - August 2, 2018 Category: Molecular Biology Authors: Nevenka Dudvarski Stankovi ć , Frank Bicker , Stefanie Keller , David TW Jones , Patrick N Harter , Arne Kienzle , Clarissa Gillmann , Philipp Arnold , Anna Golebiewska , Olivier Keunen , Alf Giese , Andreas von Deimling , Tobias Source Type: research

miR ‐205 mediates adaptive resistance to MET inhibition via ERRFI1 targeting and raised EGFR signaling
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - July 24, 2018 Category: Molecular Biology Authors: Cristina Migliore , Elena Morando , Elena Ghiso , Sergio Anastasi , Vera P Leoni , Maria Apicella , Davide Cora' , Anna Sapino , Filippo Pietrantonio , Filippo De Braud , Amedeo Columbano , Oreste Segatto , Silvia Giordano Source Type: research

Microglia P2X4 receptors as pharmacological targets for demyelinating diseases
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - July 23, 2018 Category: Molecular Biology Authors: Francesco Di Virgilio , Alba Clara Sarti Source Type: research

AAV ‐mediated gene therapy as a strategy to fight obesity and metabolic diseases
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - July 18, 2018 Category: Molecular Biology Authors: Carlos Henrique Sponton , Shingo Kajimura Source Type: research