High ‐affinity interactions and signal transduction between Aβ oligomers and TREM2
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - October 19, 2018 Category: Molecular Biology Authors: Christian B Lessard,
Samuel L Malnik,
Yingyue Zhou,
Thomas B Ladd,
Pedro E Cruz,
Yong Ran,
Thomas E Mahan,
Paramita Chakrabaty,
David M Holtzman,
Jason D Ulrich,
Marco Colonna,
Todd E Golde Source Type: research
A promising, novel, and unique BACE1 inhibitor emerges in the quest to prevent Alzheimer's disease
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - October 15, 2018 Category: Molecular Biology Authors: Justyna A Dobrowolska Zakaria,
Robert J Vassar Source Type: research
Cancer immunotherapy in routine cost ‐effective cancer care?
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - October 15, 2018 Category: Molecular Biology Authors: Sir Marc Feldmann Source Type: research
Rapamycin rescues mitochondrial myopathy via coordinated activation of autophagy and lysosomal biogenesis
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - October 11, 2018 Category: Molecular Biology Authors: Gabriele Civiletto,
Sukru Anil Dogan,
Raffaele Cerutti,
Gigliola Fagiolari,
Maurizio Moggio,
Costanza Lamperti,
Cristiane Beninc á,
Carlo Viscomi,
Massimo Zeviani Source Type: research
Reinstating plasticity and memory in a tauopathy mouse model with an acetyltransferase activator
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - October 2, 2018 Category: Molecular Biology Authors: Snehajyoti Chatterjee,
Raphaelle Cassel,
Anne Schneider ‐Anthony,
Karine Merienne,
Brigitte Cosquer,
Laura Tzeplaeff,
Sarmistha Halder Sinha,
Manoj Kumar,
Piyush Chaturbedy,
Muthusamy Eswaramoorthy,
Stéphanie Le Gras,
Céline Keime,
Olivier Source Type: research
Early auto ‐immune targeting of photoreceptor ribbon synapses in mouse models of multiple sclerosis
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - September 28, 2018 Category: Molecular Biology Authors: Mayur Dembla,
Ajay Kesharwani,
Sivaraman Natarajan,
Claudia Fecher ‐Trost,
Richard Fairless,
Sarah K Williams,
Veit Flockerzi,
Ricarda Diem,
Karin Schwarz,
Frank Schmitz Source Type: research
USP14 inhibition corrects an in vivo model of impaired mitophagy
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - September 24, 2018 Category: Molecular Biology Authors: Joy Chakraborty,
Sophia Stockum,
Elena Marchesan,
Federico Caicci,
Vanni Ferrari,
Aleksandar Rakovic,
Christine Klein,
Angelo Antonini,
Luigi Bubacco,
Elena Ziviani Source Type: research
Modulation of three key innate immune pathways for the most common retinal degenerative diseases
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - September 17, 2018 Category: Molecular Biology Authors: Isha Akhtar ‐Schäfer
,
Luping Wang
,
Tim U Krohne
,
Heping Xu
,
Thomas Langmann Source Type: research
MicroRNA therapy for infected wounds
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - September 17, 2018 Category: Molecular Biology Authors: Paul Hiebert
,
Sabine Werner Source Type: research
The BACE ‐1 inhibitor CNP520 for prevention trials in Alzheimer's disease
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - September 17, 2018 Category: Molecular Biology Authors: Ulf Neumann
,
Mike Ufer
,
Laura H Jacobson
,
Marie ‐Laure Rouzade‐Dominguez
,
Gunilla Huledal
,
Carine Kolly
,
Rainer M Lüönd
,
Rainer Machauer
,
Siem J Veenstra
,
Konstanze Hurth
,
Heinrich Rueeger
,
Marina Tintelnot‐Blomle Source Type: research
In vivo generation of human CD19 ‐CAR T cells results in B‐cell depletion and signs of cytokine release syndrome
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - September 17, 2018 Category: Molecular Biology Authors: Anett Pfeiffer
,
Frederic B Thalheimer
,
Sylvia Hartmann
,
Annika M Frank
,
Ruben R Bender
,
Simon Danisch
,
Caroline Costa
,
Winfried S Wels
,
Ute Modlich
,
Renata Stripecke
,
Els Verhoeyen
,
Christian J Buchholz Source Type: research
OXA1L mutations cause mitochondrial encephalopathy and a combined oxidative phosphorylation defect
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - September 10, 2018 Category: Molecular Biology Authors: Kyle Thompson
,
Nicole Mai
,
Monika Ol áhová
,
Filippo Scialó
,
Luke E Formosa
,
David A Stroud
,
Madeleine Garrett
,
Nichola Z Lax
,
Fiona M Robertson
,
Cristina Jou
,
Andres Nascimento
,
Carlos Ortez
,
Cecilia Jimenez‐Malleb Source Type: research
Mutations in TIMM50 compromise cell survival in OxPhos ‐dependent metabolic conditions
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - September 6, 2018 Category: Molecular Biology Authors: Aurelio Reyes
,
Laura Melchionda
,
Alberto Burlina
,
Alan J Robinson
,
Daniele Ghezzi
,
Massimo Zeviani Source Type: research
Selective depletion of metastatic stem cells as therapy for human colorectal cancer
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - September 6, 2018 Category: Molecular Biology Authors: Mar ía Virtudes Céspedes
,
Ugutz Unzueta
,
Anna Aviñó
,
Alberto Gallardo
,
Patricia Álamo
,
Rita Sala
,
Alejandro Sánchez‐Chardi
,
Isolda Casanova
,
María Antònia Mangues
,
Antonio Lopez‐Pousa
,
Ramón Eritja
,
Antonio Source Type: research
Stress signaling in breast cancer cells induces matrix components that promote chemoresistant metastasis
EMBO Molecular Medicine, EarlyView. (Source: EMBO Molecular Medicine)
Source: EMBO Molecular Medicine - September 6, 2018 Category: Molecular Biology Authors: Jacob Insua ‐Rodríguez
,
Maren Pein
,
Tsunaki Hongu
,
Jasmin Meier
,
Arnaud Descot
,
Camille M Lowy
,
Etienne De Braekeleer
,
Hans‐Peter Sinn
,
Saskia Spaich
,
Marc Sütterlin
,
Andreas Schneeweiss
,
Thordur Oskarsson Source Type: research