Seroprevalence of parvovirus B19 infection in patients with beta thalassemia major in Fayoum University Hospital
Conclusion Parvovirus B19 infection is detected in high rates among children with beta thalassemia major. Measures to avoid iatrogenic and nosocomial transmission have to be implemented including screening of donated blood for B19 especially blood given to patients with hematological disorders. Also data from this study support the need for introduction of an approved B19 vaccine that primarily protects children with thalassemia major against that infection. (Source: Egyptian Pediatric Association Gazette)
Source: Egyptian Pediatric Association Gazette - July 16, 2016 Category: Pediatrics Source Type: research

Impact of functional constipation on psychosocial functioning and quality of life of children: A cross sectional study
Conclusion Emotional and behavioral problems are common in children with FC so as quality of life which is compromised in those children and their parents suggesting incorporation of behavioral and quality of life screening into their diagnostic workup. (Source: Egyptian Pediatric Association Gazette)
Source: Egyptian Pediatric Association Gazette - June 10, 2016 Category: Pediatrics Source Type: research

Feminizing adrenal tumor in a 6-year-old boy
Publication date: Available online 30 May 2016 Source:Egyptian Pediatric Association Gazette Author(s): Hend M. Soliman, Mona Hafez, Gamal Eltagy, Ahmed Fares A 6-year-old boy presented with bilateral gynecomastia and breast tenderness. The condition started since 1year before medical consultation with gradual onset and progressive course of breast enlargement and accelerated growth with no history of any nipple discharge. There was no history of drug intake or chronic diseases. Investigations showed picture of pseudo precocious puberty with advanced bone age, suppressed LH, FSH and high estradiol (E2). Adrenal...
Source: Egyptian Pediatric Association Gazette - May 30, 2016 Category: Pediatrics Source Type: research

The health-related quality of life in normal and obese children
Conclusion Obesity in children had a negative impact on their quality of life. (Source: Egyptian Pediatric Association Gazette)
Source: Egyptian Pediatric Association Gazette - May 27, 2016 Category: Pediatrics Source Type: research

Effect of antiepileptic drug (valproic acid) on children growth
Conclusion Childhood and adolescence are crucial periods in which to attain peak bone mass, and it is a crucial period for growth in general; and most patients with epilepsy are diagnosed and treated in this period, therefore, AEDs, and especially VPA, should be used with caution in pediatric patients with epilepsy. (Source: Egyptian Pediatric Association Gazette)
Source: Egyptian Pediatric Association Gazette - May 20, 2016 Category: Pediatrics Source Type: research

Novel biomarkers for pulmonary hypertension in children with ventricular septal defect
Conclusion Galectin-3 and H-FABP are promising cardiac biomarker for prediction and risk stratification of PH in children with VSD. (Source: Egyptian Pediatric Association Gazette)
Source: Egyptian Pediatric Association Gazette - May 16, 2016 Category: Pediatrics Source Type: research

Diagnostic value of platelet parameters versus interleukin-6 in children with urinary tract infection
Conclusion Platelet indices could be used as an indicator of UTI in children. It could predict the type of causative organism. Further researches are needed to evaluate its role for detection of recurrence of UTI in high risk children. (Source: Egyptian Pediatric Association Gazette)
Source: Egyptian Pediatric Association Gazette - May 7, 2016 Category: Pediatrics Source Type: research

Effect of early procedural pain experience on subsequent pain responses among premature infants
Conclusion On studying the physiological and behavioral responses to pain in the premature infants, it was found that prior pain exposure and the number of procedures predict dampened behavioral and exaggerated physiologic subsequent pain responses. Protocols for minimization of pain exposure and pain control need to be implemented to avoid infant distress and long-term neurodevelopmental sequelae. (Source: Egyptian Pediatric Association Gazette)
Source: Egyptian Pediatric Association Gazette - April 15, 2016 Category: Pediatrics Source Type: research

Efficacy and safety of cefpodoxime in the treatment of acute otitis media in children
Conclusion Cefpodoxime proxetil is an effective, safe, well-tolerated antimicrobial agent for treatment of acute otitis media in children. It can be considered as an excellent choice for the empirical treatment of bacterial AOM. (Source: Egyptian Pediatric Association Gazette)
Source: Egyptian Pediatric Association Gazette - April 3, 2016 Category: Pediatrics Source Type: research

Diagnostic utility of biomarkers in diagnosis of early stages of neonatal sepsis in neonatal intensive care unit in Egypt
Conclusion The area under ROC curve (AUC) of TNF and CRP in the diagnosis of sepsis was superior to determinations of IL-1 and IL-6. From our data analysis and based on our financial backgrounds, we can conclude that abnormal of CRP levels together with immature-to-total neutrophil ratio above 0.2 with or without elevated IL-1, IL-6 or TNF can be used as early markers of sepsis in neonates. (Source: Egyptian Pediatric Association Gazette)
Source: Egyptian Pediatric Association Gazette - March 21, 2016 Category: Pediatrics Source Type: research

Serum levels of 25(OH) vitamin D and immunoglobulin E in infants with bronchiolitis
Conclusions Serum 25(OH) vitamin D was found in decreased quantities in infants with bronchiolitis and it was negatively correlated with serum IgE, suggesting that vitamin D may play a role in the pathogenesis of bronchiolitis. (Source: Egyptian Pediatric Association Gazette)
Source: Egyptian Pediatric Association Gazette - March 20, 2016 Category: Pediatrics Source Type: research

Use of early pulse oximetry in the detection of cardiac lesions among asymptomatic term newborns
Conclusion Pulse oximetry can be used as a tool in apparently healthy term newborns for the early detection of cardiac lesions that might necessitate specialized follow-up and care. An initial test after the age of 2h followed by a confirmatory test 2h later, with a cut-off value of <95% is proposed. A comprehensive study is necessary to validate the results of this study. This might be of significant importance in low-income communities. (Source: Egyptian Pediatric Association Gazette)
Source: Egyptian Pediatric Association Gazette - February 26, 2016 Category: Pediatrics Source Type: research

Toll-like receptors 7 and 8 mRNA in monocytes of Egyptian children with chronic hepatitis C infection genotype 4 as predictor to “response” interferon and ribavirin treatment
Conclusions TLRs 7&8 and TNF have great importance in controlling HCV infection and the responses to IFN therapy. Further research covering other stages of CHC at large numbers and at different monocytes subsets levels will be needed. (Source: Egyptian Pediatric Association Gazette)
Source: Egyptian Pediatric Association Gazette - February 9, 2016 Category: Pediatrics Source Type: research

Intestinal tuberculosis and Crohn: A clinician’s diagnostic dilemma
Publication date: Available online 21 January 2016 Source:Egyptian Pediatric Association Gazette Author(s): Seema Pavaman Sindgikar, Rathika Damodar Shenoy, Vijaya Shenoy, Raghu Shankar A 12year old girl with altered bowel habits, hematochezia and growth failure was evaluated for intestinal tuberculosis and inflammatory bowel disease and was ultimately diagnosed to have Crohn disease. This case is being reported to highlight the difficulty in differentiating inflammatory bowel disease from gastrointestinal tuberculosis in Asia Pacific region. (Source: Egyptian Pediatric Association Gazette)
Source: Egyptian Pediatric Association Gazette - January 22, 2016 Category: Pediatrics Source Type: research

Detection of viral acute lower respiratory tract infection in hospitalized infants using real-time PCR
Conclusions RV was the most commonly detected virus in children under 3years admitted with acute lower respiratory tract infections. Coinfection was present in the majority of our patients; however it was not related significantly to parameters of disease severity. (Source: Egyptian Pediatric Association Gazette)
Source: Egyptian Pediatric Association Gazette - January 12, 2016 Category: Pediatrics Source Type: research