Canadian Journal of Kidney Health and Disease This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Should temporary hemodialysis catheter insertion remain a requirement of nephrology residency training?
Abstract Purpose of review Recently, there has been much debate about the practicality and utility of training nephrology fellows in temporary hemodialysis catheter insertion. Sources of information Literature review along with the authors’ opinion. Findings This skill can be taught easily, in a controlled fashion to maximize success and minimize complications. In order to achieve this tr...
Source: Canadian Journal of Kidney Health and Disease - March 5, 2015 Category: Urology & Nephrology Source Type: research

A population-based study of prevalence and risk factors of chronic kidney disease in León, Nicaragua
Conclusions Our findings are comparable to those found in regional studies and further support the hypothesis of a Mesoamerican Nephropathy. (Source: Canadian Journal of Kidney Health and Disease)
Source: Canadian Journal of Kidney Health and Disease - February 24, 2015 Category: Urology & Nephrology Source Type: research

Development of a hemodialysis safety checklist using a structured panel process
Conclusions A novel 17-item Hemodialysis Safety Checklist (Hemo Pause) for use by nurses and patients has been developed to standardize the hemodialysis procedure. Further quality improvement efforts are underway to explore the feasibility of using this checklist to reduce adverse events and strengthen the safety culture in the hemodialysis unit. (Source: Canadian Journal of Kidney Health and Disease)
Source: Canadian Journal of Kidney Health and Disease - February 12, 2015 Category: Urology & Nephrology Source Type: research

Reviewer acknowledgement 2014
Contributing reviewers The Editors of Canadian Journal of Kidney Health and Disease would like to thank all our reviewers who have contributed to the journal in Volume 1 (2014). (Source: Canadian Journal of Kidney Health and Disease)
Source: Canadian Journal of Kidney Health and Disease - February 10, 2015 Category: Urology & Nephrology Source Type: research

The use of tissue plasminogen activator as continuous infusion into an arteriovenous hemodialysis access in the hemodialysis unit: a case series
Conclusions To our knowledge this small case series is the first to describe the procedure whereby low dose tissue plasminogen activator is directly infused into the fistula by the vascular access nurse in the dialysis unit during dialysis and not in the interventional suite. This provides additional information to the existing literature that there is an alternative option for dialysis units to diminish clot burden until a more permanent solution is established through angioplasty. (Source: Canadian Journal of Kidney Health and Disease)
Source: Canadian Journal of Kidney Health and Disease - January 30, 2015 Category: Urology & Nephrology Source Type: research

Validating a scoring tool to predict acute kidney injury (AKI) following cardiac surgery
Conclusions The modified Cleveland Clinic tool was valid in identifying patients with severe stages of AKI but did not have strong discrimination for early AKI stages. (Source: Canadian Journal of Kidney Health and Disease)
Source: Canadian Journal of Kidney Health and Disease - January 30, 2015 Category: Urology & Nephrology Source Type: research

Urinary monocyte chemoattractant protein-1 levels and interstitial changes in the renal cortex and their relationship with loss of renal function in renal transplant patients with delayed graft function
Conclusions Our results demonstrate increased levels of uMCP-1 in transplant patients with DGF, in addition to increased tubulointerstitial macrophage infiltration and RCIA, which could predict the outcome of renal function in these patients. (Source: Canadian Journal of Kidney Health and Disease)
Source: Canadian Journal of Kidney Health and Disease - January 30, 2015 Category: Urology & Nephrology Source Type: research

Efficacy and safety data of subsequent entry biologics pertinent to nephrology practice: a systematic review
Conclusions Little clinical difference was found between epoetin SEBs and the reference product. Although not deemed clinically important, the financial implication of a possible dose difference between epoetin zeta and reference product should be considered in pharmacoeconomic studies. Ongoing trials are expected to address the risk of pure-red-cell aplasia with HX 575. (Source: Canadian Journal of Kidney Health and Disease)
Source: Canadian Journal of Kidney Health and Disease - December 23, 2014 Category: Urology & Nephrology Source Type: research

Potential impact of subsequent entry biologics in nephrology practice in Canada
This report provides an executive summary of the information required to guide decisions to use or implement subsequent entry biologics by comparing Canadian regulations to other developed nations, discussing their clinical issues and predicting their impact on the Canadian market and nephrology practice. We hope that this review will assist clinicians and policy makers to navigate this complex subject and to make informed decisions in the best interest of their patients. Sources of information Sources of information include published lit...
Source: Canadian Journal of Kidney Health and Disease - December 19, 2014 Category: Urology & Nephrology Source Type: research

Kidney function, albuminuria and life expectancy
Conclusion The presence and degree of albuminuria was associated with lower estimated life expectancy for both gender and was especially notable in those with eGFR ≥30 mL/min/1.73 m2. Life expectancy associated with a given level of eGFR differs substantially based on the presence and severity of albuminuria. (Source: Canadian Journal of Kidney Health and Disease)
Source: Canadian Journal of Kidney Health and Disease - December 19, 2014 Category: Urology & Nephrology Source Type: research

Organ donation and transplantation in Canada: insights from the Canadian Organ Replacement Register
Abstract Purpose of review To provide an overview of the transplant component of the Canadian Organ Replacement Register (CORR). Findings CORR is the national registry of organ failure in Canada. It has existed in some form since 1972 and currently houses data on patients with end-stage renal disease and solid organ transplants (kidney and/or non-kidney). The transplant component of CORR receives data on a voluntary basis from individual transplant centres and organ procurem...
Source: Canadian Journal of Kidney Health and Disease - December 9, 2014 Category: Urology & Nephrology Source Type: research

The Steroids In the Maintenance of remission of Proliferative Lupus nephritis (SIMPL) pilot trial
Conclusions The high proportion of eligible patients recruited, and success of protocol adherence suggest a large trial of prednisone maintenance therapy compared to withdrawal is feasible. Trial registration Current Controlled Trials ISRCTN31327267. (Source: Canadian Journal of Kidney Health and Disease)
Source: Canadian Journal of Kidney Health and Disease - November 28, 2014 Category: Urology & Nephrology Source Type: research

Canadian chronic kidney disease clinics: a national survey of structure, function and models of care
Conclusions The variability in clinic structure and function offers an opportunity to explore the relationship of these elements to patient outcomes, and to determine optimal models of care. This list of contacts generated through this study, serves as a basis for establishing a CKD clinic network. This network is anticipated to facilitate the conduct of clinical trials to test novel interventions or strategies within the context of well characterized models of care. (Source: Canadian Journal of Kidney Health and Disease)
Source: Canadian Journal of Kidney Health and Disease - November 18, 2014 Category: Urology & Nephrology Source Type: research

A budget impact analysis of the introduction of erythropoiesis stimulating agent subsequent entry biologics for the treatment of anemia of chronic kidney disease in Canada
Conclusion The advent of SEBs represents an opportunity to relieve financial pressure in our healthcare system. Under the assumption that the efficacy and safety of epoetin SEBs are non-inferior to originator products, we have shown that the adoption of epoetin SEBs can lead to cost savings for the Canadian payer. (Source: Canadian Journal of Kidney Health and Disease)
Source: Canadian Journal of Kidney Health and Disease - November 11, 2014 Category: Urology & Nephrology Source Type: research

Health care prioritization: a clinician’s duty
Abstract Purpose of review Publicly funded health care systems are increasingly confronted with fiscal and demographic challenges and face pressure to constrain resource use without impacting clinical outcomes. Findings Clinicians routinely make decisions in the care of their patients that use finite health care resources. Aligning the goal of caring for their patients with ensuring that effective interventions are available for patients who are most likely to benefit is cri...
Source: Canadian Journal of Kidney Health and Disease - October 28, 2014 Category: Urology & Nephrology Source Type: research