Patient and stone characteristics associated with surgical intervention in pediatrics
Conclusion Stone size > 6mm and composition with calcium oxalate but not patient age or symptoms associated with presentation predicted surgical intervention. These observations can be used to inform decisions as to whether urolithiasis should be surgically managed electively or observed. (Source: Canadian Journal of Kidney Health and Disease)
Source: Canadian Journal of Kidney Health and Disease - June 2, 2015 Category: Urology & Nephrology Source Type: research

Validation of kidney transplantation using administrative data
Conclusions Codes in CORR, CIHI, and OHIP each operate well in the detection of kidney transplant recipients. These data sources can be used to efficiently identify and follow kidney transplant recipients for post-transplant outcomes. (Source: Canadian Journal of Kidney Health and Disease)
Source: Canadian Journal of Kidney Health and Disease - May 18, 2015 Category: Urology & Nephrology Source Type: research

PTHrP-related Hypercalcaemia in Infancy and Congenital Anomalies of the Kidney and Urinary Tract (CAKUT)
Conclusions The possibility of elevated PTHrP levels must be considered in patients with known renal dysplasia who are differentially diagnosed with hypercalcaemia. (Source: Canadian Journal of Kidney Health and Disease)
Source: Canadian Journal of Kidney Health and Disease - May 11, 2015 Category: Urology & Nephrology Source Type: research

Role of vascular function in predicting arteriovenous fistula outcomes: an observational pilot study
Conclusions Microvascular endothelial function as measured using PAT may be useful as a predictor of AVF maturation and function. This simple non invasive marker of vascular function may be a useful tool to predict AVF outcomes. (Source: Canadian Journal of Kidney Health and Disease)
Source: Canadian Journal of Kidney Health and Disease - May 4, 2015 Category: Urology & Nephrology Source Type: research

Inhibiting the progression of arterial calcification with vitamin K in HemoDialysis patients (iPACK-HD) trial: rationale and study design for a randomized trial of vitamin K in patients with end stage kidney disease
Discussion Vitamin K supplementation is a simple, safe and cost-effective nutritional strategy that can easily be integrated into patient care. If vitamin K reduces the progression of coronary artery calcification it may lead to decreased morbidity and mortality in men and women with ESKD. Trial registration NCT 01528800. (Source: Canadian Journal of Kidney Health and Disease)
Source: Canadian Journal of Kidney Health and Disease - May 1, 2015 Category: Urology & Nephrology Source Type: research

CKD in disadvantaged populations
(Source: Canadian Journal of Kidney Health and Disease)
Source: Canadian Journal of Kidney Health and Disease - April 29, 2015 Category: Urology & Nephrology Source Type: research

An education initiative modifies opinions of hemodialysis nurses towards home dialysis
Conclusions CNE initiatives can modify the opinions of in-center HD nurses towards home modalities and should complement the multitude of strategies aimed at promoting home dialysis. (Source: Canadian Journal of Kidney Health and Disease)
Source: Canadian Journal of Kidney Health and Disease - April 28, 2015 Category: Urology & Nephrology Source Type: research

Strategies to increase living kidney donation: a retrospective cohort study
Conclusion The implementation of a LOD team, combined with our participation in the LDPE registry, was associated with a significant increase in the actual number of living kidney transplantations performed. These data support initiatives such as the creation of dedicated LOD teams and LDPE registry to increase LKT. (Source: Canadian Journal of Kidney Health and Disease)
Source: Canadian Journal of Kidney Health and Disease - April 21, 2015 Category: Urology & Nephrology Source Type: research

Oral salt and water versus intravenous saline for the prevention of acute kidney injury following contrast-enhanced computed tomography: study protocol for a pilot randomized trial
Discussion The results of this pilot trial will provide critical information to plan a definitive trial to test the efficacy of the route of volume loading regimens in prevention of acute kidney injury after contrast-enhanced CT scans. Trial registration The trial is registered at the US National Institutes of Health (ClinicalTrials.gov) # NCT02084771. (Source: Canadian Journal of Kidney Health and Disease)
Source: Canadian Journal of Kidney Health and Disease - April 16, 2015 Category: Urology & Nephrology Source Type: research

A modified Delphi process to identify process of care indicators for the identification, prevention and management of acute kidney injury after major surgery
Conclusions These indicators can be used to measure and improve the quality of care for AKI after major surgery. (Source: Canadian Journal of Kidney Health and Disease)
Source: Canadian Journal of Kidney Health and Disease - April 9, 2015 Category: Urology & Nephrology Source Type: research

Acute kidney injury: an acceptable risk of treatment with renin-angiotensin system blockade in primary care?
Conclusions Use of RAS antagonists increased the risk of AKI, independent of common confounding variables. After correction for confounders the risk fell away and became non-significant for moderate and severe AKI. However, where there was no evidence-based indication for RAS antagonists the risk of AKI, whether mild, moderate or severe, remained greater. (Source: Canadian Journal of Kidney Health and Disease)
Source: Canadian Journal of Kidney Health and Disease - April 9, 2015 Category: Urology & Nephrology Source Type: research

Benefits and harms of citrate locking solutions for hemodialysis catheters: a systematic review and meta-analysis
Abstract Background Citrate has theoretical advantages over heparin for locking hemodialysis central venous catheters (CVCs), but the comparative effectiveness of these agents is not clear. Objectives 1) To compare the benefits and harms of citrate versus heparin locking solutions among patients undergoing hemodialysis through CVCs; 2) to appraise methodological quality of the supporting evidence. Data sources ...
Source: Canadian Journal of Kidney Health and Disease - April 2, 2015 Category: Urology & Nephrology Source Type: research

Should nephrologists take a larger role in interventional nephrology, and should central line insertion remain a requirement of nephrology residency training? A debate
Abstract The Canadian Society of Nephrology must soon provide input concerning the future of procedural training in nephrology. While at one time, the ability to insert a central venous catheter (CVC) was an essential skill required by all nephrologists, in 2014, nephrology training and practice has changed in fundamental ways such that it would be both unreasonable, and impractical, to maintain this requirement. Indeed, survey evidence suggests that many current trainees are not achieving this competency. Amongst the reasons that this requirement should be withdrawn include: 1) Not all trainees have th...
Source: Canadian Journal of Kidney Health and Disease - April 2, 2015 Category: Urology & Nephrology Source Type: research

Mass screening for chronic kidney disease in rural and remote Canadian first nations people: methodology and demographic characteristics
Conclusions Point of care mass screening, real time risk prediction and counselling of First Nations people at high risk of Kidney Failure is feasible in rural and remote communities. Further analysis of this cohort will describe theepidemiology of CKD in these communities, and test the cost effectiveness of this strategy. (Source: Canadian Journal of Kidney Health and Disease)
Source: Canadian Journal of Kidney Health and Disease - March 19, 2015 Category: Urology & Nephrology Source Type: research

Percutaneous native renal biopsy adequacy: a successful interdepartmental quality improvement activity
Conclusions Restricting the performance of biopsies to subspecialist operators, including an adequacy statement in the renal biopsy report and on-site adequacy assessment were effective in significantly improving native renal biopsy adequacy. This improvement appeared unrelated to an increase in the number of passes taken with a biopsy needle. Neither initiative improved the low adequacy of allograft biopsies. (Source: Canadian Journal of Kidney Health and Disease)
Source: Canadian Journal of Kidney Health and Disease - March 13, 2015 Category: Urology & Nephrology Source Type: research