Quinine controls body weight gain without affecting food intake in male C57BL6 mice
Conclusion:
Quinine contributes to weight control in male C57BL6 mice without affecting food intake. A partial contribution of Trpm5 to quinine dependent body weight control is suggested. (Source: BMC Physiology - Latest articles)
Source: BMC Physiology - Latest articles - February 8, 2013 Category: Physiology Authors: Philippe Cettour-RoseCarole BezençonChristian DarimontJohannes le CoutreSami Damak Source Type: research
Importance of uncharged polar residues and proline in the proximal two-thirds (Pro107¿Ser128) of the highly conserved region of mouse ileal Na+-dependent bile acid transporter, Slc10a2, in transport activity and cellular expression
Conclusions:
The functional importance of proline and uncharged polar residues in the highly conserved region of mouse Slc10a2 was determined. This information will contribute to the design of bile acid-conjugated prodrugs for efficient drug delivery or SLC10A2 inhibitors for hypercholesterolemia treatment. (Source: BMC Physiology - Latest articles)
Source: BMC Physiology - Latest articles - February 4, 2013 Category: Physiology Authors: Tohru SaekiKosuke SatoShiho ItoKeisuke IkedaRyuhei Kanamoto Source Type: research
Importance of uncharged polar residues and proline in the proximal two-thirds (Pro107--Ser128) of the highly conserved region of mouse ileal Na+-dependent bile acid transporter, Slc10a2, in transport activity and cellular expression
Conclusions:
The functional importance of proline and uncharged polar residues in the highly conserved region of mouse Slc10a2 was determined. This information will contribute to the design of bile acid-conjugated prodrugs for efficient drug delivery or SLC10A2 inhibitors for hypercholesterolemia treatment. (Source: BMC Physiology - Latest articles)
Source: BMC Physiology - Latest articles - February 4, 2013 Category: Physiology Authors: Tohru SaekiKosuke SatoShiho ItoKeisuke IkedaRyuhei Kanamoto Source Type: research
The antioxidant response of the liver of male Swiss mice raised on a AIN 93 or commercial diet
Conclusions:
The clear differences in antioxidant responses observed in the livers of mice fed on the two diets suggest that the macro- and micro-nutrient components with antioxidant properties, including vitamin E, can promote changes in the activity of enzymes involved in the removal of the ROS generated by cell metabolism. (Source: BMC Physiology - Latest articles)
Source: BMC Physiology - Latest articles - January 24, 2013 Category: Physiology Authors: Aline CaetanoLucimara da VeigaFlávia CapaldiSeverino de AlencarRicardo AzevedoRosangela Bezerra Source Type: research
Genomic homeostasis is dysregulated in favour of apoptosis in the colonic epithelium of the azoxymethane treated rat
Conclusions:
The healthy rats' colon exhibits extensive gene expression changes between its proximal and distal ends. The most common changes are associated with metabolism, but more subtle expression changes in genes involved in genomic homeostasis are also evident. These latter changes presumably protect and maintain a healthy colonic epithelium against incidental dietary and environmental insults. AOM induces substantial changes in gene expression, resulting in an early switch in the cell cycle process, involving p53 signalling, towards cell cycle arrest leading to the more effective process of apoptosis to counteract t...
Source: BMC Physiology - Latest articles - January 23, 2013 Category: Physiology Authors: Caroline KerrBarney HinesJanet ShawRobert DunneLauren BraggJulie ClarkeTrevor LockettRichard Head Source Type: research
Disease resistance is related to inherent swimming performance in Atlantic salmon
Conclusions:
This is the first evidence suggesting that inherent swimming performance is associated with disease resistance in fish. (Source: BMC Physiology - Latest articles)
Source: BMC Physiology - Latest articles - January 21, 2013 Category: Physiology Authors: Vicente CastroBarbara Grisdale-HellandSven JørgensenJan HelgerudGuy ClaireauxAnthony FarrellAleksei KrasnovStåle HellandHarald Takle Source Type: research
HOXA4 protein levels and localization in the aorta and in human abdominal aortic aneurysms
This report presents evidence for the specificities of select commercially available HOXA4 antibodies in regards to concerns about the specificity of the HOXA4 antibody used by Lillvis et al. (Regional expression... (Source: BMC Physiology)
Source: BMC Physiology - December 14, 2011 Category: Physiology Authors: Christian Klausen and Nelly Auersperg Source Type: research
Male silver eels mature by swimming
If European silver eels are prevented from reproductive migration, they remain in a prepubertal stage by dopaminergic inhibition of pituitary activity. Because this inhibition is likely a requirement for an ex... (Source: BMC Physiology)
Source: BMC Physiology - July 10, 2008 Category: Physiology Authors: Arjan P Palstra, Denhi Schnabel, Maaike C Nieveen, Herman P Spaink and Guido EEJM van den Thillart Source Type: research
Human cortical perfusion and the arterial pulse: a near-infrared spectroscopy study
The pulsatile nature of the arterial pulse induces a pulsatile perfusion pattern which can be observed in human cerebral cortex with non-invasive near-infrared spectroscopy. The present study attempts to estab... (Source: BMC Physiology)
Source: BMC Physiology - April 27, 2004 Category: Physiology Authors: Hon C Kwan, Anita Cheng, Ruth Liu and Donald S Borrett Source Type: research
Red light accelerates and melatonin retards metamorphosis of frog tadpoles
Earlier studies from this laboratory reported that light and its spectra influence reproduction in the Indian skipper frog Rana cyanophlyctis through both ocular and extra ocular photoreception. During the course... (Source: BMC Physiology)
Source: BMC Physiology - September 17, 2003 Category: Physiology Authors: Bhaskar N Joshi and Khaja Mohinuddin Source Type: research
