Cross-reactive antibodies against H7N9 and H5N1 avian influenza viruses in Thai population
Conclusions: Anti-NA antibody has broader reactivity than anti-HA antibody, therefore, it can be a supplement to anti-HA antibody in the prevention against novel influenza viruses. (Source: Asian Pacific Journal of Allergy and Immunology)
Source: Asian Pacific Journal of Allergy and Immunology - August 20, 2016 Category: Allergy & Immunology Source Type: research

Enhancement and regulation effect of myrcene on antibody response in immunization with ovalbumin and Ag85B in mice
Conclusions: Myrcene enhanced specific immune responses against OVA and Ag85B. This study suggested the tendency of the enhancement of Th1 immune response by myrcene.Key words: Ag85B, adjuvant, antigen-specific immune response, myrcene, ovalbumin (Source: Asian Pacific Journal of Allergy and Immunology)
Source: Asian Pacific Journal of Allergy and Immunology - August 7, 2016 Category: Allergy & Immunology Source Type: research

Novel characterisation of mast cell phenotypes from peripheral blood mononuclear cells in chronic fatigue syndrome/myalgic encephalomyelitis patients
Conclusions: This preliminary study investigates mast cell phenotypes from PBMCs in healthy controls. We report  significant increase of naïve MCs in moderate and severe CFS/ME patients compared with healthy controls. Moreover, a significant increase in CD40 ligand and MHC-II receptors on differentiated mast cells in severe CFS/ME patients. Peripheral MCs may be present in CFS/ME pathology however, further investigation to determine their role is required.Key words: Chronic Fatigue Syndrome; Mast Cells; Receptor for advanced glycation end products; RAGE; Ligand High Mobility Group Box 1 protein (HMGB1); Myalgic Encephal...
Source: Asian Pacific Journal of Allergy and Immunology - July 23, 2016 Category: Allergy & Immunology Source Type: research

Effect of the prenatal maternal environments and diets on cord blood interleukin-4 and interferon –gamma: A pilot study
Conclusions: In this study, a strong association between IL-4 and IFN- γ levels in cord blood and the intake of folate and vitamin B6 was found, which indicates that food intake during pregnancy might have a strong influence on IL-4 and IFN-γ levels in cord blood, to a greater extent than environmental factors. (Source: Asian Pacific Journal of Allergy and Immunology)
Source: Asian Pacific Journal of Allergy and Immunology - June 27, 2016 Category: Allergy & Immunology Source Type: research

The correlation of serum eosinophil cationic protein level with eosinophil count, and total IgE level in Korean adult allergic rhinitis patients
Conclusions: We suggest that ECP could be an important mediator in the pathogenesis of AR. The level of serum ECP was positively correlated with eosinophilia in AR patients regardless of the type of allergen sensitization. However, further study is warranted to verify the role of ECP in the clinical management of allergic rhinitis.Key words: eosinophil cationic protein, immunoglobulin E, eosinophil count, allergic rhinitis, MAST DOI  10.12932/AP0739 (Source: Asian Pacific Journal of Allergy and Immunology)
Source: Asian Pacific Journal of Allergy and Immunology - June 25, 2016 Category: Allergy & Immunology Source Type: research

Patterns and risk factors of causative contact allergens in Thai adult patients with contact dermatitis
Conclusions: There was an alteration in the pattern of contact sensitization detected by our standard series. MCI/MI has become the most common preservative causing contact allergy. (Source: Asian Pacific Journal of Allergy and Immunology)
Source: Asian Pacific Journal of Allergy and Immunology - June 25, 2016 Category: Allergy & Immunology Source Type: research

Fraction of exhaled nitric oxide and soluble receptors for advanced glycation end products are negatively correlated in children with recurrent wheezing
Conclusions: FeNO and sRAGE serum levels are negatively correlated in children with recurrent wheezing. Further larger scale studies are needed to test the use of FeNO and sRAGE as biomarkers for the prediction of asthma in children. (Source: Asian Pacific Journal of Allergy and Immunology)
Source: Asian Pacific Journal of Allergy and Immunology - June 25, 2016 Category: Allergy & Immunology Source Type: research

Effects of seasonal smog on asthma and COPD exacerbations requiring emergency visits in Chiang Mai, Thailand
Conclusions: This study confirms the effect of increasing PM10 concentrations from seasonal smog on asthma and COPD exacerbations. However, there was an approximately 1 week lag time between the elevated PM10 levels and time toemergency visits due to disease exacerbation.Key words: asthma, chronic obstructive pulmonary disease, pollution, exacerbation, emergency DOI 10.12932/AP0668 (Source: Asian Pacific Journal of Allergy and Immunology)
Source: Asian Pacific Journal of Allergy and Immunology - May 20, 2016 Category: Allergy & Immunology Source Type: research

Comparison of different histamine concentrations used as a skin prick test positive control
Conclusion: Locally-prepared histamine base at concentrations of 5 and 10 mg/mL yielded better positive results than both imported and locally-prepared histamine at a concentration of 1 mg/mL. (Source: Asian Pacific Journal of Allergy and Immunology)
Source: Asian Pacific Journal of Allergy and Immunology - May 14, 2016 Category: Allergy & Immunology Source Type: research

Comparison between specific IgE levels and skin prick test results of local and imported American cockroach, dog, cat, dust mites and mold allergen extracts
Conclusions: When the SPT results are compared between local and imported allergen extracts, all were found to have significant agreement, with very good agreement for cat allergens. When the SPT results are compared with specific IgE levels, both local and imported allergen extract provided comparable validity. (Source: Asian Pacific Journal of Allergy and Immunology)
Source: Asian Pacific Journal of Allergy and Immunology - May 7, 2016 Category: Allergy & Immunology Source Type: research

Strategies to improve the immunogenicity of prM+E dengue virus type-2 DNA vaccine
Conclusion: The strategy of the C-terminal region chimeric counterpart with JE20 did not improve but may have reduced the induction of neutralizing antibodies. (Source: Asian Pacific Journal of Allergy and Immunology)
Source: Asian Pacific Journal of Allergy and Immunology - March 20, 2016 Category: Allergy & Immunology Source Type: research

Regulatory T, natural killer T and γδ T cells in multiple sclerosis and chronic fatigue syndrome/myalgic encephalomyelitis: a comparison
Conclusion: This study has not identified immunological disturbances that are common in both MS and CFS/ME patients. However differential expression of cell types between the conditions investigated suggests different pathways of disease. These differences need to be explored in further studies.DOI 10.12932/AP0733 (Source: Asian Pacific Journal of Allergy and Immunology)
Source: Asian Pacific Journal of Allergy and Immunology - March 20, 2016 Category: Allergy & Immunology Source Type: research

Perilla leaf extract prevents atopic dermatitis induced by an extract of Dermatophagoides farinae in NC/Nga mice
Conclusion: The results indicated that PLE may inhibit the symptoms of AD.  Keywords: Perilla leaf extract, NC/Nga mice, atopic dermatitis, IgE antibody, periostin, thymus and activation-regulated chemokine DOI 10.12932/AP0717 (Source: Asian Pacific Journal of Allergy and Immunology)
Source: Asian Pacific Journal of Allergy and Immunology - March 20, 2016 Category: Allergy & Immunology Source Type: research

Atopic dermatitis: recent insight on pathogenesis and novel therapeutic target
< p > Atopic dermatitis (AD) is   the most common chronic inflammatory skin disease . It affects infancy, but it is also highly prevalent in adults and it is cause of  burden to patients and their families. Nowaday, AD is  recognized as an heterogenous disease, including different subtypes with variable clinical manifestations, in which the impairments of the skin barrier are crucial. The severity of AD dictates the level of treatment. Current AD treatment focuses on restoration of barrier function, mainly through moisturizers and on the control of inflammation by the use of corticosteroids, topical calcineurin inhibit...
Source: Asian Pacific Journal of Allergy and Immunology - March 20, 2016 Category: Allergy & Immunology Source Type: research

Identification of wheat sensitization using an in-house wheat extract in Coca-10% alcohol solution in children with wheat anaphylaxis
Conclusion: The in-house prepared Coca-10% EtOH solution could extract both water/salt and alcohol soluble allergens. The ~35 kDa gliadin appears to be a major wheat allergen among tested individuals. < /strong > < /p > < p > < strong > < br / > < /strong > < /p > < p > < strong > DOI   < /strong > < strong > 10.12932/AP0696.34.2.2016 < /strong > < /p > (Source: Asian Pacific Journal of Allergy and Immunology)
Source: Asian Pacific Journal of Allergy and Immunology - March 20, 2016 Category: Allergy & Immunology Source Type: research