AJP: Regulatory, Integrative and Comparative Physiology AJP: Regulatory, Integrative and Comparative Physiology RSS feedThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Salt control. Focus on "High salt induces autocrine actions of ET-1 on inner medullary collecting duct NO production via upregulated ETB receptor expression"
(Source: AJP: Regulatory, Integrative and Comparative Physiology)
Source: AJP: Regulatory, Integrative and Comparative Physiology - August 11, 2016 Category: Physiology Authors: Just, A. Tags: Editorial Focus Source Type: research

Glycine enhances muscle protein mass associated with maintaining Akt-mTOR-FOXO1 signaling and suppressing TLR4 and NOD2 signaling in piglets challenged with LPS
Pro-inflammatory cytokines play a critical role in the pathophysiology of muscle atrophy. We hypothesized that glycine exerted an anti-inflammatory effect and alleviated lipopolysaccharide (LPS)-induced muscle atrophy in piglets. Pigs were assigned to four treatments including the following: 1) nonchallenged control, 2) LPS-challenged control, 3) LPS+1.0% glycine, and 4) LPS+2.0% glycine. After receiving the control, 1.0 or 2.0% glycine-supplemented diets, piglets were treated with either saline or LPS. At 4 h after treatment with saline or LPS, blood and muscle samples were harvested. We found that 1.0 or 2.0% glycine inc...
Source: AJP: Regulatory, Integrative and Comparative Physiology - July 31, 2016 Category: Physiology Authors: Liu, Y., Wang, X., Wu, H., Chen, S., Zhu, H., Zhang, J., Hou, Y., Hu, C.-A. A., Zhang, G. Tags: Hormones, Reproduction and Development Source Type: research

Long-lasting bradypnea induced by repeated social defeat
In conclusion, social stress induces sustained chronic bradypnea mediated by DMH neurons and NTS 5-HT3 receptors. These changes are associated with an anxiety-like state that persists until D+10, followed by recovery. However, bradypnea may persist in one-half of the population up until D+30, despite apparent recovery of the anxiety-like state. (Source: AJP: Regulatory, Integrative and Comparative Physiology)
Source: AJP: Regulatory, Integrative and Comparative Physiology - July 31, 2016 Category: Physiology Authors: Brouillard, C., Carrive, P., Camus, F., Benoliel, J.-J., Similowski, T., Sevoz-Couche, C. Tags: Neural Control Source Type: research

Effects of a ketogenic diet on adipose tissue, liver, and serum biomarkers in sedentary rats and rats that exercised via resisted voluntary wheel running
In conclusion, KD rats presented a healthier metabolic profile, albeit the employed exercise protocol minimally impacts any potentiating effects that KD has on fat loss. (Source: AJP: Regulatory, Integrative and Comparative Physiology)
Source: AJP: Regulatory, Integrative and Comparative Physiology - July 31, 2016 Category: Physiology Authors: Holland, A. M., Kephart, W. C., Mumford, P. W., Mobley, C. B., Lowery, R. P., Shake, J. J., Patel, R. K., Healy, J. C., McCullough, D. J., Kluess, H. A., Huggins, K. W., Kavazis, A. N., Wilson, J. M., Roberts, M. D. Tags: Physical Activity and Inactivity Source Type: research

Seasonal changes in brown adipose tissue mitochondria in a mammalian hibernator: from gene expression to function
Brown adipose tissue (BAT) is a thermogenic organ that is vital for hibernation in mammals. Throughout the hibernation season, BAT mitochondrial uncoupling protein 1 (UCP1) enables rapid rewarming from hypothermic torpor to periodic interbout arousals (IBAs), as energy is dissipated as heat. However, BAT's unique ability to rewarm the body via nonshivering thermogenesis is not necessary outside the hibernation season, suggesting a potential seasonal change in the regulation of BAT function. Here, we examined the BAT mitochondrial proteome and mitochondrial bioenergetics in the thirteen-lined ground squirrel (Ictidomys trid...
Source: AJP: Regulatory, Integrative and Comparative Physiology - July 31, 2016 Category: Physiology Authors: Ballinger, M. A., Hess, C., Napolitano, M. W., Bjork, J. A., Andrews, M. T. Tags: Obesity, Diabetes and Energy Homeostasis Source Type: research