Acta Psychiatrica Scandinavica Supplementum 
This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.
This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Sleep and circadian rhythms in mood disorders.
CONCLUSION: Diagnostic classification schemas and clinical features of depression may influence sleep EEG findings, but gender may be a more important consideration.
PMID: 17280576 [PubMed - indexed for MEDLINE] (Source: Acta Psychiatrica Scandinavica Supplementum)
Source: Acta Psychiatrica Scandinavica Supplementum - March 9, 2013 Category: Psychiatry Tags: Acta Psychiatr Scand Suppl Source Type: research
Does dopamine dysfunction drive depression?
CONCLUSION: DA is a credible aetiological candidate for the PMD in melancholic depression. However, melancholia needs first to be characterized both clinically and in terms of its pathophysiology. In this regard, illnesses such as bipolar depression and Parkinson's disease warrant consideration as they provide suitable models of both the cognitive and motor aspects of PMD, and hold the necessary markers to better define melancholia.
PMID: 17280577 [PubMed - indexed for MEDLINE] (Source: Acta Psychiatrica Scandinavica Supplementum)
Source: Acta Psychiatrica Scandinavica Supplementum - March 9, 2013 Category: Psychiatry Tags: Acta Psychiatr Scand Suppl Source Type: research
Treatment response in melancholia.
CONCLUSION: The research data, in the aggregate, suggest that the presence of melancholia predicts a poor response to psychotherapy and placebo and a relatively good response to antidepressants and ECT.
PMID: 17280578 [PubMed - indexed for MEDLINE] (Source: Acta Psychiatrica Scandinavica Supplementum)
Source: Acta Psychiatrica Scandinavica Supplementum - March 9, 2013 Category: Psychiatry Tags: Acta Psychiatr Scand Suppl Source Type: research
Electroconvulsive therapy in melancholia: the role of hippocampal neurogenesis.
CONCLUSION: We hypothesize that the superior antimelancholic effect of induced seizures may be understood in the light of the powerful control of neural plasticity exerted by the regulation of the hypothalamic-pituitary-adrenal axis and, perhaps, other regulatory factors.
PMID: 17280579 [PubMed - indexed for MEDLINE] (Source: Acta Psychiatrica Scandinavica Supplementum)
Source: Acta Psychiatrica Scandinavica Supplementum - March 9, 2013 Category: Psychiatry Tags: Acta Psychiatr Scand Suppl Source Type: research
Depot antipsychotic medications in bipolar disorder: a review of the literature.
CONCLUSION: After a careful risk-benefit analysis, depot antipsychotics may be considered for the long-term control of mood episodes in bipolar patients who have relapsed due to medication non-adherence or who have failed to respond to standard therapies. Depot FGAs should be avoided in patients with a high burden of illness from depressive symptoms and particularly in those judged to be at high risk of suicide. The available data on depot formulations of SGAs indicate that they are efficacious in the maintenance treatment of bipolar illness without increasing the burden of the depressive pole of the illness, but further s...
Source: Acta Psychiatrica Scandinavica Supplementum - March 9, 2013 Category: Psychiatry Tags: Acta Psychiatr Scand Suppl Source Type: research
Neuropsychological functioning in euthymic bipolar disorder: a meta-analysis.
CONCLUSION: Meta-analytic findings provide evidence of a trait-related neuropsychological deficit in bipolar disorder involving attention/processing speed, memory, and executive function. Findings are discussed with regard to potential moderators, etiologic considerations, limitations, and future directions in neuropsychological research on bipolar disorder.
PMID: 17688459 [PubMed - indexed for MEDLINE] (Source: Acta Psychiatrica Scandinavica Supplementum)
Source: Acta Psychiatrica Scandinavica Supplementum - March 9, 2013 Category: Psychiatry Tags: Acta Psychiatr Scand Suppl Source Type: research
Adjunctive treatment of acute mania: a clinical overview.
CONCLUSION: The available placebo-controlled randomized clinical trials support adjunctive therapy combining lithium or valproate with olanzapine, risperidone, haloperidol or quetiapine. The additional increment of antimanic efficacy of these combinations over monotherapy was similar in magnitude to that seen for the same agents as monotherapy in comparison with placebo. These additive benefits enhanced the tolerability of adverse effects sufficiently to allow a higher proportion of subjects receiving combination therapies to complete the studies than monotherapy treated patients. The available data has several shortcoming...
Source: Acta Psychiatrica Scandinavica Supplementum - March 9, 2013 Category: Psychiatry Tags: Acta Psychiatr Scand Suppl Source Type: research
Vascular mania: an old concept in danger of sclerosing? A clinical overview.
CONCLUSION: Further studies are needed to determine whether mania associated with vascular disease is a specific and separate sub-type with a late-age at onset. An alternative framework for considering vascular mania is proposed.
PMID: 17688461 [PubMed - indexed for MEDLINE] (Source: Acta Psychiatrica Scandinavica Supplementum)
Source: Acta Psychiatrica Scandinavica Supplementum - March 9, 2013 Category: Psychiatry Tags: Acta Psychiatr Scand Suppl Source Type: research
Dopamine dysregulation syndrome: implications for a dopamine hypothesis of bipolar disorder.
CONCLUSION: Pharmacological models suggest a role of increased dopaminergic drive in mania and the converse in depression. In Parkinson's disease, administration of high-dose dopamine precursors can produce a 'maniform' picture, which switches into a depressive analogue on withdrawal. It is possible that in bipolar disorder there is a cyclical process, where increased dopaminergic transmission in mania leads to a secondary down regulation of dopaminergic receptor sensitivity over time. This may lead to a period of decreased dopaminergic transmission, corresponding with the depressive phase, and the repetition of the cycle....
Source: Acta Psychiatrica Scandinavica Supplementum - March 9, 2013 Category: Psychiatry Tags: Acta Psychiatr Scand Suppl Source Type: research
A 6-month randomized open-label comparison of continuation of oral atypical antipsychotic therapy or switch to long acting injectable risperidone in patients with bipolar disorder.
CONCLUSION: LAI-ris demonstrated similar effectiveness, safety and tolerability compared to oral AAP in this 6 month pilot trial.
PMID: 17688463 [PubMed - indexed for MEDLINE] (Source: Acta Psychiatrica Scandinavica Supplementum)
Source: Acta Psychiatrica Scandinavica Supplementum - March 9, 2013 Category: Psychiatry Tags: Acta Psychiatr Scand Suppl Source Type: research
Measuring mania metabolites: a longitudinal proton spectroscopy study of hypomania.
CONCLUSION: This exploratory study of BD demonstrates significant differences in metabolite levels that vary both with respect to brain region and mood state. Not withstanding the confounding effects of medication and the limitation of small sample size the findings are important as they demonstrate that a longitudinal approach is a useful design especially in the context of a long-term phasic illness.
PMID: 17688464 [PubMed - indexed for MEDLINE] (Source: Acta Psychiatrica Scandinavica Supplementum)
Source: Acta Psychiatrica Scandinavica Supplementum - March 9, 2013 Category: Psychiatry Tags: Acta Psychiatr Scand Suppl Source Type: research
Outcome evaluation needed to support evidence-based practice! Preface.
Authors: Malm U, Eberhard J
PMID: 17953520 [PubMed - indexed for MEDLINE] (Source: Acta Psychiatrica Scandinavica Supplementum)
Source: Acta Psychiatrica Scandinavica Supplementum - March 9, 2013 Category: Psychiatry Tags: Acta Psychiatr Scand Suppl Source Type: research
Five-year follow-up during antipsychotic treatment: efficacy, safety, functional and social outcome.
CONCLUSION: The findings underline the chronicity and seriousness of psychotic disorders in terms of social outcome and, indirectly, the low quality of life of this group of persons. Patients were generally well aware of their illness and able to sort out symptoms from drug side effects. This opens for more active involvement of patients in monitoring their own treatment.
PMID: 17953521 [PubMed - indexed for MEDLINE] (Source: Acta Psychiatrica Scandinavica Supplementum)
Source: Acta Psychiatrica Scandinavica Supplementum - March 9, 2013 Category: Psychiatry Tags: Acta Psychiatr Scand Suppl Source Type: research
Clinical decision-making during 5 years of antipsychotic treatment.
CONCLUSION: The decision-making process appears to have many unknown components, and may benefit from more active patient involvement by using structured clinician and patient rating scales for monitoring the treatment. Such shared decision-making may improve compliance.
PMID: 17953522 [PubMed - indexed for MEDLINE] (Source: Acta Psychiatrica Scandinavica Supplementum)
Source: Acta Psychiatrica Scandinavica Supplementum - March 9, 2013 Category: Psychiatry Tags: Acta Psychiatr Scand Suppl Source Type: research
Nicotine use and its correlates in patients with psychosis.
CONCLUSION: A parsimonious interpretation of the findings is that patients suffering from psychosis fail to desist from nicotine rather than experience significant positive effects of the usage.
PMID: 17953523 [PubMed - indexed for MEDLINE] (Source: Acta Psychiatrica Scandinavica Supplementum)
Source: Acta Psychiatrica Scandinavica Supplementum - March 9, 2013 Category: Psychiatry Tags: Acta Psychiatr Scand Suppl Source Type: research
