Xeno-Free Autologous Platelet Rich Plasma for Chronic Wound Management – Case Series
Conclusion Our study demonstrates that single dose of non-activated PRP is an efficacious treatment regime for chronic wounds. Further, it eliminates need for multiple doses due to continual release of growth factor over a long period of time, thus considerably reducing effective cost of procedure. (Source: Wound Medicine)
Source: Wound Medicine - February 1, 2018 Category: General Medicine Source Type: research
Effective debridement with micro water jet technology (MWT): A retrospective clinical application observation of 90 patients with acute and chronic wounds
Conclusion The result of the retrospective data analysis on patients with predominantly chronic and persistent wounds shows that debriding with micro water jet technology is an efficient, tissue-preserving, precise and time-saving method for outpatient wound care – with excellent healing outcomes. Patient safety was high and we have seen no adverse effects. The MWT is comparable to other water jet-based cleaning/rinsing systems. (Source: Wound Medicine)
Source: Wound Medicine - January 10, 2018 Category: General Medicine Source Type: research
Lifetime cost of chronic ulcers requiring hospitalization in Ontario, Canada: a population-based study
Conclusions Chronic ulcers present a substantial economic burden to the health care system. Health care decision makers are encouraged to consider additional resources to preventative interventions for chronic ulcers to reduce downstream costs. (Source: Wound Medicine)
Source: Wound Medicine - January 6, 2018 Category: General Medicine Source Type: research
Therapeutic effects of a pulsed electromagnetic device in chronic cutaneous ulcers of the lower limbs
Publication date: Available online 9 December 2017 Source:Wound Medicine Author(s): Edoardo Raposio, Nicolò Bertozzi, Francesco Simonacci, Michele P. Grieco We conducted a randomized, prospective pilot study to evaluate the therapeutic effects (in particular, wound healing rate and pain relief) of one device that administers topical millimeter waves (MW) in patients with chronic skin ulcers of the lower extremities. Twenty consecutive patients with chronic skin ulcers of the lower extremities were enrolled in the study and were assigned alternatingly into two groups (experimental and control) as they randomly arrive...
Source: Wound Medicine - December 10, 2017 Category: General Medicine Source Type: research
Modulation of collagen population under honey assisted wound healing in diabetic rat model
Conclusions Based on these findings, it might be opined that honey predominantly helps in regulating synthesis, glycation and deposition followed by mechanical quality of collagen alike normal skin and its application also accelerated diabetic healing process. (Source: Wound Medicine)
Source: Wound Medicine - December 8, 2017 Category: General Medicine Source Type: research
Extracorporeal shockwave therapy as supplemental therapy for closure of large full thickness defects —Rat full-thickness skin graft model
The objective of this study was to evaluate effects of single and repeated ESWT on skin graft survival and healing. (Source: Wound Medicine)
Source: Wound Medicine - November 25, 2017 Category: General Medicine Source Type: research
A systematic review of whirlpool as an adjunctive treatment for cellulitis
Conclusions No conclusion could be reached from this systematic review since no study met the eligibility criteria from the results generated. (Source: Wound Medicine)
Source: Wound Medicine - November 19, 2017 Category: General Medicine Source Type: research
Dose regulated cutaneous wound healing potential of quercetin in male rats
In conclusion, quercetin at 0.1% concentration has pronounced pro-healing potential in male rats. (Source: Wound Medicine)
Source: Wound Medicine - November 19, 2017 Category: General Medicine Source Type: research
Hydroalcoholic extract from Lepidium meyenii (Black Maca) root exerts wound healing activity in Streptozotocin-induced diabetic rats
Conclusion The present study is the first report on wound healing properties of BME in diabetic rats. (Source: Wound Medicine)
Source: Wound Medicine - November 19, 2017 Category: General Medicine Source Type: research
Surgical approach choice and efficiency of complementary therapies in treatment of pilonidal cyst: Meta-analysis and treatment algorithm
Publication date: December 2017 Source:Wound Medicine, Volume 19 Author(s): Vladimir N. Obolenskiy The article presents literature review (website PubMed is used) on the advantages and disadvantages of one-stage and two-stage surgical treatment of pylonidal cyst, meta-analysis of published data on the efficiency of gentamicin-impregnated collagen implants, vacuum-assisted wound closure and platelet growth factors in treatment of this pathology. Treatment results of 87 patients with pilonidal cyst with postoperative observation period from 1 to 5 years have been analyzed. Algorithm of therapeutic approach selection for s...
Source: Wound Medicine - November 19, 2017 Category: General Medicine Source Type: research
Human microflora, Probiotics and Wound healing
This article reviews the recent literature on the effect of human microflora, both cutaneous and gastrointestinal, on wound healing process. In addition, the latest advancements in the use of the normal microflora members that are beneficial to the host, the so-called probiotics, as a new therapeutic agent in wound management are presented and analyzed. A better understanding of the influence of microflora on wound healing, may lead to therapeutics that improve the wound management and resolve impaired wounds. (Source: Wound Medicine)
Source: Wound Medicine - September 29, 2017 Category: General Medicine Source Type: research
Treatment of skin and soft tissue infections caused by Pseudomonas aeruginosa —A review of our experiences with citric acid over the past 20 years
Publication date: December 2017 Source:Wound Medicine, Volume 19 Author(s): Basavraj Nagoba, Milind Davane, Rajan Gandhi, Bharat Wadher, Namdev Suryawanshi, Sohan Selkar Multiple antibiotic resistant Pseudomonas aeruginosa is a significant cause of burn wound infections and, skin and soft tissue infections. Because of its resistance to commonly used antibiotics and antiseptics, there is a shortage of therapeutic options for effective treatment. The present review summarizes the use of citric acid as a most potential substitute for antiseptics to control pseudomonal wound infections and its role in the process of wo...
Source: Wound Medicine - September 25, 2017 Category: General Medicine Source Type: research
Development and characterization of nanofibrous mat from PVA/Tridax Procumbens (TP) leaves extracts
Publication date: Available online 22 September 2017 Source:Wound Medicine Author(s): P Ganesan, P Pradeepa In this work an attempt made biodegradable polymer of PVA (10% conc.) blended with methanol extract of Tridax Procumbens (TP) leaves (10% conc.) in the ratio of 80/20 and electrospun into nanofibrous mat. Nanofibrous mat was characterized by basic properties like thickness, porosity, density. The Porosity of the nanofibrous mat was analyzed by using capillary flow porometer and result showed that it has largest pore diameter at 2.26 microns. The morphological studies to evaluate the diameter and surface structure...
Source: Wound Medicine - September 23, 2017 Category: General Medicine Source Type: research
Treatment of Skin and Soft Tissue Infections Caused by Pseudomonas aeruginosa − A Review of our Experiences with Citric Acid Over the Past 20 Years
Publication date: Available online 21 September 2017 Source:Wound Medicine Author(s): Basavraj Nagoba, Milind Davane, Rajan Gandhi, Bharat Wadher, Namdev Suryawanshi, Sohan Selkar Multiple antibiotic resistant Pseudomonas aeruginosa is a significant cause of burn wound infections and, skin and soft tissue infections. Because of its resistance to commonly used antibiotics and antiseptics, there is a shortage of therapeutic options for effective treatment. The present review summarizes the use of citric acid as a most potential substitute for antiseptics to control pseudomonal wound infections and its role in the pro...
Source: Wound Medicine - September 22, 2017 Category: General Medicine Source Type: research
Wound healing activity of 3, 3 ′, 4′-Trihydroxyflavone, isolated from Justicia wynaadensis
The objective of the present study was to determine the wound healing activity of 3, 3′, 4′-Trihydroxyflavone by excision wound model in diabetic rats. Diabetes induced rats (blood glucose level >250mg/dL) with 25mm diameter of wound area were topically administered with 25 and 50mg/kg BW of 3,3′,4′-trihydroxyflavone daily for 28 days. The blood glucose level and wound contraction rate was measured at weekly intervals. Histopathological studies were carried out on skin, excised from the wound area after the experimental period. Blood glucose levels remained above 250mg/dL in diabetes induced animals. The con...
Source: Wound Medicine - September 22, 2017 Category: General Medicine Source Type: research
