Cost Comparison of Split Thickness Skin Grafting with and without Bilayer Dermal Regenerative Templates for Bilateral Axillary Hidradenitis Suppurativa: A Retrospective Comparison Study
Conclusion: Bilateral axillary hidradenitis is a chronic, suppurative, and scarring disease process that is most effectively treated by complete excision of all hair-bearing tissues. Split thickness skin grafting without use of bilayer dermal regenerative templates yielded definitive results with acceptable cosmesis and functionality without the added cost of the bilayer dermal regenerative template. (Source: Wound Medicine)
Source: Wound Medicine - April 11, 2015 Category: Journals (General) Source Type: research
In-vitro study on endotoxin release of gram-negative bacteria after contact with silver releasing compared to DACC coated wound dressings
Publication date: Available online 8 April 2015 Source:Wound Medicine Author(s): Florian H.H. Brill , Horst Braunwarth , Dietmar Becher The treatment of critically colonized or locally infected wounds with local antimicrobial agents is a standard of care. The destruction of especially gram-negative bacteria potentially increases the endotoxin level in the wound. This in-vitro study aims to answer the question of whether and to what extent endotoxin release caused by the destruction of gram-negative bacteria is influenced by different wound dressing. Silver ion releasing dressings were compared to wound dressings wit...
Source: Wound Medicine - April 9, 2015 Category: Journals (General) Source Type: research
The German national consensus on wound documentation and outcomes: Rationale, working program and current status
Conclusions Based on a national joint process involving medical societies, nursing groups, German sickness funds and health politics, a continuous decision process on standards for outcomes measurement and interpretation could be established. The Delphi based decision processes showed high levels of participations, thus providing a valid and robust set of standards. First results are in process of approval by the societies. (Source: Wound Medicine)
Source: Wound Medicine - April 2, 2015 Category: Journals (General) Source Type: research
The role of biomedical sensors in wound healing
Publication date: Available online 26 March 2015 Source:Wound Medicine Author(s): P. Salvo , V. Dini , F. Di Francesco , M. Romanelli Acute and chronic wounds have a tremendous impact on patients’ life conditions. As wound healing involves a huge number of biochemical processes, biomedical sensors play a major role for wound monitoring and early detection of infections. This paper describes and discusses the sensors currently under research that can provide invaluable information on the different phases of wound healing. These sensors can allow wound healing to be continuously monitored, thus opening the path for...
Source: Wound Medicine - March 27, 2015 Category: Journals (General) Source Type: research
Evaluation of wound healing activity of Acacia caesia in rats
Publication date: Available online 26 March 2015 Source:Wound Medicine Author(s): Sembian Suriyamoorthy , Kalidass Subramaniam , Jeevan Raj Durai. S , Femina Wahaab , Pemila Edith Chitraselvi. R. Acacia caesia (L) is a leguminous perennial climbing shrub belonging to the family Mimosaceae, and is native to south-east Asia. Despite the traditional practice of using the bark juice for wound healing there is no scientific report on the wound healing properties of this plant. Ethno pharmacologically the bark of Acacia caesia has significant prohealing activity. The higher levels of alkaloids, flavonoids, glycosides a...
Source: Wound Medicine - March 27, 2015 Category: Journals (General) Source Type: research
Avicenna's views on factors affecting wound healing
In this study as a literature review we have explained briefly the views of Ibn Sina (Avicenna) on wounds and factors affecting wound healing, his classification on wounds and the measures are to be taken for observing wound healing and have reviewed them in accordance with the new findings on this subject. As a result from comparing these two methods we found that despite restrictions and limitations of Avicenna's time, many of his measures and recommendations on the treatment of wounds, are completely compatible and consistent with new scientific findings in this field. (Source: Wound Medicine)
Source: Wound Medicine - March 27, 2015 Category: Journals (General) Source Type: research
Interim Results for A Prospective, Randomized, Double-Blind Multicenter Study Comparing Continuous Diffusion of Oxygen Therapy to standard Moist Wound Therapy in the Treatment of Diabetic Foot Ulcers
We examined planned interim data of a prospective, randomized, double-blind multi-center study comparing the clinical efficacy of the TransCu O2 ® device to standard moist wound therapy (MWT). The therapy, known as Continuous Diffusion of Oxygen (CDO), delivers pure oxygen to the wound at low flow rates, preserves patient mobility, showed significant benefits in animal studies and received FDA clearance in August 2009. We summarize here the results of a per protocol interim analysis of complete wound closure at 12 weeks in a double blind 2-arm clinical trial of 84 subjects randomized 1:1 to Active CDO versus Sham, conduc...
Source: Wound Medicine - March 27, 2015 Category: Journals (General) Source Type: research
Patient-Reported Outcomes as Diagnostic Tools and Clues in Chronic Wounds: Considerations for Practice
Conclusion Patient-reported outcomes are mandatory for the diagnostic work-up of chronic wounds. They also provide essential information in the course of disease, can be diagnostic clues for non-adherence and treatment failures and reflect patient orientation in treatment. Measurement of many PRO parameters in wound disease, such as health-related quality of life and pain, is facilitated by validated instruments, which are recommended for practice. (Source: Wound Medicine)
Source: Wound Medicine - March 27, 2015 Category: Journals (General) Source Type: research
The Quest for Tissue Repair's Holy Grail: The Promise of Wound Diagnostics or Just another Fishing Expedition?
Publication date: Available online 27 March 2015 Source:Wound Medicine Author(s): David G. Armstrong , Eric J. Lew , Bonnie Hurwitz , Thomas Wild In both Celtic and later Norman Arthurian legend, the Fisher King was a man charged with keeping and protecting the Holy Grail. He suffered from perpetual non-healing wounds, which could only be healed once the hero and most worthy of knights, Perceval, could answer the question “who does the Grail serve?” In this manuscript, we ask the same question in a slightly more modern context. It has become evident that perpetually using empiricism and clinical guesswork alone...
Source: Wound Medicine - March 27, 2015 Category: Journals (General) Source Type: research
Development and Validation of a Short Version of the Freiburg Life Quality Assessment for Chronic Venous Disease (FLQA-VS-10)
Conclusion This short version of the Freiburg Life Quality Assessment for venous diseases (FLQA-VS-10) with 10 items is an easy-to-use instrument for assessing health-related quality of life. It demonstrated validity and feasibility and can be used in practice and research. (Source: Wound Medicine)
Source: Wound Medicine - February 13, 2015 Category: Journals (General) Source Type: research
Comparison of acellular small intestinal matrix (ASIM) and 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide crosslinked ASIM (ASIM-EDC) for repair of full-thickness skin wounds in rabbits
In this study, an acellular small intestinal matrix (ASIM) of bubaline origin was prepared using sodium deoxycholate. In order to reduce the immunogenicity, we crosslinked it using 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride (EDC). Healing potential of ASIM and ASIM-EDC were compared in full-thickness skin wounds in rabbits. Eighteen clinically healthy New Zealand white rabbits of either sex were randomly divided into three equal groups. Under anesthesia, four full-thickness skin wounds (20×20mm each) were produced on the dorsum of each rabbit. Wounds in control (I) were left open, whereas, in ASIM (II) an...
Source: Wound Medicine - January 23, 2015 Category: Journals (General) Source Type: research
Wound bed preparation: The impact of debridement and wound cleansing
Publication date: July 2013 Source:Wound Medicine, Volume 1 Author(s): Lars-Peter Kamolz , Thomas Wild Wound healing is a complex series of events that are interlinked and dependent on one another. Acute wounds usually follow a well-defined process. In the past this model of healing has been applied also to chronic wounds, but it is well known that chronic wound healing is different from acute wound healing. Wound bed preparation as a concept allows the clinician to focus systematically on all of the critical components of a non-healing wound to identify the cause of the problem, and implement a care programme in ord...
Source: Wound Medicine - December 8, 2014 Category: Journals (General) Source Type: research
Antimicrobial activity of wound antiseptics against Extended-Spectrum Beta-Lactamase-producing bacteria
In conclusion, our in vitro data demonstrate that commonly used wound antiseptic agents are effective against ESBL-producing bacteria. Furthermore, no influence of the antibiotic-resistance on the efficacy of the antiseptic agents tested or a higher resistance against strains used in standard methods could be observed. (Source: Wound Medicine)
Source: Wound Medicine - December 8, 2014 Category: Journals (General) Source Type: research
German S3-Clinical Practice Guideline: Topical treatment of chronic wounds at patients with the risks of occlusive arterial disease, diabetes mellitus, chronic venous insufficiency Importance and consequences for wound management
Publication date: July 2013 Source:Wound Medicine, Volume 1 Author(s): Michael Schmitz The management of patients with chronic wounds is a great and demanding challenge. Several and partly contradictory approaches, different treatments and unmanageable amount of dressings lead in confusion and uncertainty. A concerted recommendation is essential to improve the patient centred care and the use of health care system resources. With these leading points as background the DGfW (Deutsche Gesellschaft für Wundheilung und Wundbehandlung e.V. [German society of wound healing and wound treatment]) initiated the German S3-Clin...
Source: Wound Medicine - December 8, 2014 Category: Journals (General) Source Type: research
How a targeted reduction in spend on wound care dressings was achieved without compromising quality of care and outcomes?
In conclusion, the project has succeeded to deliver a reduction in the spend on dressings without compromising quality. Furthermore, there is evidence of growing awareness among product user to ensure that quality outcomes are achievable by correct usage of products which in turn can only be achieved through product usage education and training. Indication management and case management are an integral part of the process and require special training. (Source: Wound Medicine)
Source: Wound Medicine - December 8, 2014 Category: Journals (General) Source Type: research
