Hip Dysplasia in the Young Adult
Hip dysplasia is a leading precursor of osteoarthritis and is seen in 20% to 40% of patients with osteoarthritis of the hip. An increase in mechanical stress on the cartilage matrix with failure of the acetabular labrum represents the major pathomechanism of degeneration. Because the prevalence of associated femoral deformities is high (>50%), the structural anatomy of the dysplastic hip must be assessed in multiple planes using radiographs and, if needed, advanced imaging modalities. Acetabular osteotomy (periacetabular and/or rotational) is the most commonly used procedure for the treatment of the majority of dyspl...
Source: The Journal of Bone and Joint Surgery - January 6, 2016 Category: Orthopaedics Authors: Gala, L., Clohisy, J. C., Beaule, P. E. Tags: Hip Current Concepts Review Source Type: research

Changes in Muscle Oxygen Saturation Have Low Sensitivity in Diagnosing Chronic Anterior Compartment Syndrome of the Leg
Conclusions: Changes in muscle oxygen saturation during and after an exercise test that elicits leg pain cannot be used to distinguish between patients with CACS and patients with other causes of exercise-induced leg pain. Level of Evidence: Diagnostic Level II. See Instructions for Authors for a complete description of levels of evidence. (Source: The Journal of Bone and Joint Surgery)
Source: The Journal of Bone and Joint Surgery - January 6, 2016 Category: Orthopaedics Authors: Rennerfelt, K., Zhang, Q., Karlsson, J., Styf, J. Tags: Sports Medicine Scientific Articles Source Type: research

Angiotensin-(1-7) Attenuates Skeletal Muscle Fibrosis and Stiffening in a Mouse Model of Extremity Sarcoma Radiation Therapy
Conclusions: Ang-(1-7) attenuated RIF, stiffening, and production of profibrotic cytokines that were elevated in mouse skeletal muscles after simulated radiation therapy for extremity sarcoma. Clinical Relevance: Ang-(1-7) may serve as a potential therapy for the prevention of RIF in patients who require radiation therapy as adjuvant treatment for soft-tissue sarcoma. (Source: The Journal of Bone and Joint Surgery)
Source: The Journal of Bone and Joint Surgery - January 6, 2016 Category: Orthopaedics Authors: Willey, J. S., Bracey, D. N., Gallagher, P. E., Tallant, E. A., Wiggins, W. F., Callahan, M. F., Smith, T. L., Emory, C. L. Tags: Basic Science, Oncology Scientific Articles Source Type: research

Comprehensive Analysis of a Recalled Modular Total Hip System and Recommendations for Management
Conclusions: Early failures of modular total hip arthroplasty occur due to fretting and corrosion at the neck-stem junction, resulting in ALTR. Surveillance utilizing metal ion levels and MRI may be indicated for all patients regardless of symptoms, as the early survivorship is poor and the ultimate failure rate may be catastrophically high. Level of Evidence: Therapeutic Level II. See Instructions for Authors for a complete description of levels of evidence. (Source: The Journal of Bone and Joint Surgery)
Source: The Journal of Bone and Joint Surgery - January 6, 2016 Category: Orthopaedics Authors: Nawabi, D. H., Do, H. T., Ruel, A., Lurie, B., Elpers, M. E., Wright, T., Potter, H. G., Westrich, G. H. Tags: Hip Scientific Articles Source Type: research

Repair of Intraoperative Injury to the Medial Collateral Ligament During Primary Total Knee Arthroplasty
Conclusions: Our results suggest that intraoperative MCL injury can be treated with primary repair followed by hinged knee bracing without the need for increased prosthetic constraint. Stiffness, however, was a common complication. Level of Evidence: Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence. (Source: The Journal of Bone and Joint Surgery)
Source: The Journal of Bone and Joint Surgery - January 6, 2016 Category: Orthopaedics Authors: Bohl, D. D., Wetters, N. G., Del Gaizo, D. J., Jacobs, J. J., Rosenberg, A. G., Della Valle, C. J. Tags: Knee Scientific Articles Source Type: research

Addition of Mesenchymal Stem Cells to Autologous Platelet-Enhanced Fibrin Scaffolds in Chondral Defects: Does It Enhance Repair?
Conclusions: APEF alone resulted in thicker repair tissue than was seen with APEF+BMDMSCs. The addition of BMDMSCs to APEF did not enhance cartilage repair and stimulated bone formation in some cartilage defects. Clinical Relevance: APEF supported repair of critical-size full-thickness chondral defects in horses, which was not improved by the addition of BMDMSCs. This work supports further investigation to determine whether APEF enhances cartilage repair in humans. (Source: The Journal of Bone and Joint Surgery)
Source: The Journal of Bone and Joint Surgery - January 6, 2016 Category: Orthopaedics Authors: Goodrich, L. R., Chen, A. C., Werpy, N. M., Williams, A. A., Kisiday, J. D., Su, A. W., Cory, E., Morley, P. S., McIlwraith, C. W., Sah, R. L., Chu, C. R. Tags: Basic Science, Sports Medicine Scientific Articles Source Type: research

Diabetes Is Related to Worse Patient-Reported Outcomes at Two Years Following Spine Surgery
Conclusions: Diabetes was associated with worse patient-reported outcomes when patients with diabetes were compared with patients without diabetes at two years following elective spine surgery. Although patients with diabetes improved when compared from baseline to the time following elective spine surgery, they did not improve to the same extent as patients without diabetes in the ODI or NDI and EQ-5D scores. Providers may use this information to counsel patients with diabetes on expectations following spine surgery. Level of Evidence: Prognostic Level II. See Instructions for Authors for a complete description of levels...
Source: The Journal of Bone and Joint Surgery - January 6, 2016 Category: Orthopaedics Authors: Armaghani, S. J., Archer, K. R., Rolfe, R., Demaio, D. N., Devin, C. J. Tags: Spine Scientific Articles Source Type: research

Effect of Compliance Counseling on Brace Use and Success in Patients with Adolescent Idiopathic Scoliosis
Conclusions: Providing patients undergoing bracing for adolescent idiopathic scoliosis with feedback about their compliance with brace wear improves that compliance. Patients who wore their brace more hours per day had less curve progression. Patients in both groups who had curve progression to a magnitude requiring surgery wore their brace less than their counterparts for whom bracing was successful. Compliance monitoring and counseling based on that monitoring should become part of the clinical orthotic management of patients with adolescent idiopathic scoliosis. Level of Evidence: Therapeutic Level II. See Instructions...
Source: The Journal of Bone and Joint Surgery - January 6, 2016 Category: Orthopaedics Authors: Karol, L. A., Virostek, D., Felton, K., Wheeler, L. Tags: Pediatrics, Spine Scientific Articles Source Type: research

Cartilage Resurfacing: Unresolved Enigma: Commentary on an article by L.R. Goodrich, DVM, PhD, et al.: "Addition of Mesenchymal Stem Cells to Autologous Platelet-Enhanced Fibrin Scaffolds in Chondral Defects. Does It Enhance Repair?"
(Source: The Journal of Bone and Joint Surgery)
Source: The Journal of Bone and Joint Surgery - January 6, 2016 Category: Orthopaedics Authors: Dahlgren, L. A. Tags: Basic Science, Sports Medicine Commentary and Perspective Source Type: research

Compliance Counseling Improves Outcomes of Bracing for Patients with Idiopathic Scoliosis: Commentary on an article by Lori A. Karol, MD, et al.: "Effect of Compliance Counseling on Brace Use and Success in Patients with Adolescent Idiopathic Scoliosis"
(Source: The Journal of Bone and Joint Surgery)
Source: The Journal of Bone and Joint Surgery - January 6, 2016 Category: Orthopaedics Authors: Reinker, K. A. Tags: Pediatrics, Spine Commentary and Perspective Source Type: research

Understanding Orthopaedic Registry Studies: A Comparison with Clinical Studies
Abstract: Orthopaedic registries are valuable for monitoring patient outcomes in real-world settings. Registries are useful for identifying procedure incidence and device utilization, evaluating outcomes, determining patients at risk for complications and reoperations, identifying devices in recall situations, assessing comparative effectiveness of procedures and devices, and providing data for research studies. In the present report, we describe how orthopaedic registries can be used to conduct research and how they compare with randomized controlled trials (RCTs) in regard to methodology. Using an example, a comparison o...
Source: The Journal of Bone and Joint Surgery - January 6, 2016 Category: Orthopaedics Authors: Inacio, M. C. S., Paxton, E. W., Dillon, M. T. Tags: Hip, Knee The Orthopaedic Forum Source Type: research

Development and Validation of Perioperative Risk-Adjustment Models for Hip Fracture Repair, Total Hip Arthroplasty, and Total Knee Arthroplasty
Conclusions: Risk-adjustment models using data from health records demonstrated good discrimination and calibration for HFR, THA, and TKA. It is possible to provide adequate risk adjustment using only the most predictive variables commonly available within the clinical record. This finding helps to inform the trade-off between model performance and data-collection burden as well as the need to define priorities for data capture from electronic health records. These models can be used to make fair comparisons of outcome measures intended to characterize provider quality of care for value-based-purchasing and registry initia...
Source: The Journal of Bone and Joint Surgery - January 6, 2016 Category: Orthopaedics Authors: Schilling, P. L., Bozic, K. J. Tags: Hip, Knee, Trauma Scientific Articles Source Type: research

Erratum
(Source: The Journal of Bone and Joint Surgery)
Source: The Journal of Bone and Joint Surgery - January 6, 2016 Category: Orthopaedics Tags: Erratum Source Type: research

Effect of Surgical Caseload on Revision Rate Following Total and Unicompartmental Knee Replacement
Conclusions: This study confirmed the importance of surgical caseload in determining the survival of UKR and, to a lesser extent, TKR. The reasons for this effect are complex and not fully explained by variables recorded in the National Joint Registry; however, the patient selection and revision threshold of lower-volume surgeons may be a factor. Examination of matched patients in this study demonstrated that high-volume surgeons can achieve revision/reoperation rates similar to those observed following TKR. Level of Evidence: Therapeutic Level III. See Instructions for Authors for a complete description of levels of evid...
Source: The Journal of Bone and Joint Surgery - January 6, 2016 Category: Orthopaedics Authors: Liddle, A. D., Pandit, H., Judge, A., Murray, D. W. Tags: Knee Scientific Articles Source Type: research

In Appreciation
(Source: The Journal of Bone and Joint Surgery)
Source: The Journal of Bone and Joint Surgery - December 16, 2015 Category: Orthopaedics Tags: In Appreciation Source Type: research