Does Age Influence the Risk of Incident Knee Osteoarthritis After a Traumatic Anterior Cruciate Ligament Injury?
Conclusion: The age at which an ACL injury is sustained does not appear to influence the rate of incident radiographic knee OA, although mature-aged athletes are likely to arrive at the OA endpoint sooner. (Source: The American Journal of Sports Medicine)
Source: The American Journal of Sports Medicine - August 31, 2016 Category: Sports Medicine Authors: Johnson, V. L., Roe, J. P., Salmon, L. J., Pinczewski, L. A., Hunter, D. J. Tags: Knee, general, Knee ligaments, ACL, Aging athlete Source Type: research

Validation of Quantitative Measures of Rotatory Knee Laxity
Conclusion: The inertial sensor and image analysis techniques were able to detect differences between low- and high-grade pivot-shift test results. A quantitative assessment of the pivot-shift test could augment the diagnosis of an ACL injury and improve the ability to detect changes in rotatory knee laxity over time. (Source: The American Journal of Sports Medicine)
Source: The American Journal of Sports Medicine - August 31, 2016 Category: Sports Medicine Authors: Musahl, V., Griffith, C., Irrgang, J. J., Hoshino, Y., Kuroda, R., Lopomo, N., Zaffagnini, S., Samuelsson, K., Karlsson, J., PIVOT Study Group, Oostdyk, Rahnemai-Azar, Arilla, Guenther, Zlotnicki, Ohashi, Araujo, Kurosaka, Nagamune, Marcheggiani Muccioli, Tags: Clinical assessment/Grading scales, Knee, general, Knee ligaments, ACL Source Type: research

The Intracellular Effect of Relaxin on Female Anterior Cruciate Ligament Cells
Conclusion: Relaxin-2 significantly upregulated intracellular processes in human female ACL cells, but no effect was observed in male cells. Relaxin increased MMP (MMP1 and MMP3) and decreased αSMA and type I and III collagen expression, which may act to alter the structural integrity of the ACL tissue over time. Clinical Relevance: Female athletes with higher circulating relaxin levels may be more susceptible to ACL injury. (Source: The American Journal of Sports Medicine)
Source: The American Journal of Sports Medicine - August 31, 2016 Category: Sports Medicine Authors: Konopka, J. A., DeBaun, M. R., Chang, W., Dragoo, J. L. Tags: Knee ligaments, ACL, Female athlete Source Type: research

Temporal Changes in Cellular Repopulation and Collagen Fibril Remodeling and Regeneration After Allograft Anterior Cruciate Ligament Reconstruction: An Experimental Study Using Kusabira-Orange Transgenic Pigs
Conclusion: Genetically engineered pigs carrying the Kusabira-Orange gene were useful animal models for analyzing intrinsic and extrinsic cellular dynamics during the course of graft healing after ACL reconstruction. Cellular repopulation by recipient cells occurred in the very early stage, and the cellular distribution within the graft resembled that in the native ACL by 24 weeks, but the reconstructed graft had not restored the ultrastructure of the native ACL by that stage. Clinical Relevance: In allograft ACL reconstruction in a pig model, cellular repopulation was completed by 24 weeks after surgery, but the collagen...
Source: The American Journal of Sports Medicine - August 31, 2016 Category: Sports Medicine Authors: Takeuchi, H., Niki, Y., Matsunari, H., Umeyama, K., Nagashima, H., Enomoto, H., Toyama, Y., Matsumoto, M., Nakamura, M. Tags: Biology of ligament, Cell/Molecular biology, Knee ligaments, ACL Source Type: research

BioCartilage Improves Cartilage Repair Compared With Microfracture Alone in an Equine Model of Full-Thickness Cartilage Loss
Conclusion: BioCartilage with PRP safely improved cartilage repair compared with MFx alone in an equine model of articular cartilage defects up to 13 months after implantation. Clinical Relevance: The 1-year results of BioCartilage + PRP suggest that homologous allograft tissue provides a safe and effective augmentation of traditional MFx. (Source: The American Journal of Sports Medicine)
Source: The American Journal of Sports Medicine - August 31, 2016 Category: Sports Medicine Authors: Fortier, L. A., Chapman, H. S., Pownder, S. L., Roller, B. L., Cross, J. A., Cook, J. L., Cole, B. J. Tags: Growth factors/Healing enhancement, Knee, articular cartilage, Biologic healing enhancement Source Type: research

Fresh Osteochondral Allograft Versus Autograft: Twelve-Month Results in Isolated Canine Knee Defects
Conclusion: After 12 months from time of implantation, fresh osteochondral allograft tissue and autograft tissue in this study were not statistically different with respect to biomechanical properties, gross morphology, bony incorporation, or overall histologic characteristics. When compared with the previously reported 6-month incorporation rates, there was improved allograft and autograft incorporation at 12 months. Clinical Relevance: With no significant differences in gross examination, radiographs, MRI, biomechanical testing, or histology in the canine model, the use of allograft tissue to treat osteochondral defects...
Source: The American Journal of Sports Medicine - August 31, 2016 Category: Sports Medicine Authors: McCarty, E. C., Fader, R. R., Mitchell, J. J., Glenn, R. E., Potter, H. G., Spindler, K. P. Tags: Biology of cartilage, Biomechanics, articular cartilage, Knee, articular cartilage, Allografts Source Type: research

Drop-Jump Landing Varies With Baseline Neurocognition: Implications for Anterior Cruciate Ligament Injury Risk and Prevention
Conclusion: Healthy athletes with lower baseline neurocognitive performance generate knee kinematic and kinetic patterns that are linked to ACL injury. Clinical Relevance: Neurocognitive testing using the CRI may be useful for identification of athletes at elevated risk for future ACL injury. (Source: The American Journal of Sports Medicine)
Source: The American Journal of Sports Medicine - August 31, 2016 Category: Sports Medicine Authors: Herman, D. C., Barth, J. T. Tags: Biomechanics, general, Injury prevention, Motion analysis/Kinesiology, Knee ligaments, ACL Source Type: research

Structural Abnormalities on Magnetic Resonance Imaging in Patients With Patellofemoral Pain: A Cross-sectional Case-Control Study
Conclusion: Structural abnormalities of the patellofemoral joint have been hypothesized as a factor in the pathogenesis of PFP, but the study findings suggest that structural abnormalities of the patellofemoral joint on MRI are not associated with PFP. (Source: The American Journal of Sports Medicine)
Source: The American Journal of Sports Medicine - August 31, 2016 Category: Sports Medicine Authors: van der Heijden, R. A., de Kanter, J. L. M., Bierma-Zeinstra, S. M. A., Verhaar, J. A. N., van Veldhoven, P. L. J., Krestin, G. P., Oei, E. H. G., van Middelkoop, M. Tags: Knee, patella, Imaging, magnetic resonance Source Type: research

Long-term Survivorship and Function of Meniscus Transplantation
Conclusion: A survival analysis that includes reoperations, MRI, radiographs, and a comprehensive examination provides a worst-case but realistic analysis of transplant function. Many patients experienced a short- and long-term benefit of reduced symptoms and improved function. However, meniscus transplants undergo a deleterious remodeling process and eventually fail. Patients should be advised that the procedure is not curative in the long term, and additional surgery will likely be required. (Source: The American Journal of Sports Medicine)
Source: The American Journal of Sports Medicine - August 31, 2016 Category: Sports Medicine Authors: Noyes, F. R., Barber-Westin, S. D. Tags: Knee, meniscus, Allografts, Articular cartilage resurfacing Source Type: research

Outcomes of Anatomic Anterior Cruciate Ligament Reconstruction: Bone-Quadriceps Tendon Graft Versus Double-Bundle Hamstring Tendon Graft
Conclusion: Anatomic ACL reconstruction with the BQT autograft showed similar knee stability and functional outcome scores when compared with the DBHT autograft. Additionally, better flexor muscle strength recovery was found in the quadriceps group, indicating a potential advantage of the BQT autograft in ACL reconstruction. (Source: The American Journal of Sports Medicine)
Source: The American Journal of Sports Medicine - August 31, 2016 Category: Sports Medicine Authors: Lee, J. K., Lee, S., Lee, M. C. Tags: Knee ligaments, ACL, General sports trauma Source Type: research

Comparison Between Single- and Double-Bundle Anterior Cruciate Ligament Reconstruction With 6- to 8-Stranded Hamstring Autograft: A Prospective, Randomized Clinical Trial
Conclusion: Both SB and DB ACL reconstruction with 6- to 8-stranded HG showed satisfactory results in subjective scores and anteroposterior and rotational stability over a nearly 7-year follow-up; neither technique was superior. (Source: The American Journal of Sports Medicine)
Source: The American Journal of Sports Medicine - August 31, 2016 Category: Sports Medicine Authors: Liu, Y., Cui, G., Yan, H., Yang, Y., Ao, Y. Tags: Knee ligaments, ACL Source Type: research

A Randomized Controlled Trial With Mean 16-Year Follow-up Comparing Hamstring and Patellar Tendon Autografts in Anterior Cruciate Ligament Reconstruction
Conclusion: Only minor and mostly insignificant differences were found between the PT and HT autograft groups in this long-term randomized controlled trial. In both groups, significantly more signs of radiographic OA were found in the reconstructed knee than in the contralateral knee. (Source: The American Journal of Sports Medicine)
Source: The American Journal of Sports Medicine - August 31, 2016 Category: Sports Medicine Authors: Björnsson, H., Samuelsson, K., Sundemo, D., Desai, N., Sernert, N., Rostgard-Christensen, L., Karlsson, J., Kartus, J. Tags: Knee ligaments, ACL, Knee, articular cartilage Source Type: research

Femoroacetabular Impingement Is Associated With Sports-Related Posterior Hip Instability in Adolescents: A Matched-Cohort Study
Conclusion: A significantly higher mean alpha angle from the superior to the anterior-superior regions of the femoral head-neck junction and lower acetabular version were found in adolescents who sustained low-energy, sports-related posterior hip dislocations. (Source: The American Journal of Sports Medicine)
Source: The American Journal of Sports Medicine - August 31, 2016 Category: Sports Medicine Authors: Mayer, S. W., Abdo, J. C. M., Hill, M. K., Kestel, L. A., Pan, Z., Novais, E. N. Tags: Hip, femoroactabular impingement Hip and Thigh Source Type: research

Intraoperative and Early Postoperative Complications After Hip Arthroscopic Surgery: A Prospective Multicenter Trial Utilizing a Validated Grading Scheme
Conclusion: The overall complication rate after hip arthroscopic surgery at tertiary hip centers was 8.3%, with higher rates reported for longer traction times (>60 minutes) and for female patients. Compared with surgical hip dislocation using the same classification system, the overall rate of complications was similar, but the rate of higher grade complications was lower for arthroscopic hip procedures. (Source: The American Journal of Sports Medicine)
Source: The American Journal of Sports Medicine - August 31, 2016 Category: Sports Medicine Authors: Larson, C. M., Clohisy, J. C., Beaule, P. E., Kelly, B. T., Giveans, M. R., Stone, R. M., Samuelson, K. M., on behalf of the ANCHOR Study Group Tags: Hip/Pelvis/Thigh, Hip, femoroactabular impingement, Hip arthroscopy Hip and Thigh Source Type: research

Predictors of Length of Career After Hip Arthroscopy for Femoroacetabular Impingement in Professional Hockey Players
Conclusion: Professional NHL players who underwent hip arthroscopy for FAI were able to continue playing for an average of 5.9 years after surgery, with 67% playing a minimum of 5 years postoperatively. Younger age and shorter duration of symptoms at time of surgery correlated with greater length of career and years played after hip arthroscopy. Players who did not play a minimum of 5 years postoperatively had significantly longer duration of symptoms before surgery. The study data support early arthroscopic treatment of professional hockey players with symptomatic FAI. (Source: The American Journal of Sports Medicine)
Source: The American Journal of Sports Medicine - August 31, 2016 Category: Sports Medicine Authors: Menge, T. J., Briggs, K. K., Philippon, M. J. Tags: Hip/Pelvis/Thigh, Hip, femoroactabular impingement, Ice hockey Hip and Thigh Source Type: research