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Intravenous treatment of migraine
Abstract: Migraine is a common primary headache disorder. A subset of patients may become disabled by frequent, severe, or treatment-refractory headache. Most patients respond adequately to drugs administered by the oral, intramuscular, or subcutaneous route. Intravenous therapy is an option for the treatment of severe headache in a monitored setting. The most common scenario is the treatment of acute refractory headache in the emergency department. Intravenous treatment may be undertaken with common analgesics, such as acetaminophen, ibuprofen, and ketorolac, or an opioid, or with a drug used specifically for migraine. Am...
Source: Techniques in Regional Anesthesia and Pain Management - January 1, 2012 Category: Anesthesiology Authors: Sait Ashina, Russell K. Portenoy Source Type: research

Acute and preventive treatment of migraine headache
Abstract: Migraine is a widespread primary headache disorder which requires a broad and an inclusive approach. This requires the use of appropriate pharmacological agents along with the integration of non-pharmacological therapies. There are 2 main categories of medication that are utilized for the treatment of migraine. Acute medications aim to relieve the pain and other symptoms associated with individual attacks and halt progression. Preventive therapies are used to reduce attack frequency, severity, and duration. There are a variety of medications available for both acute and preventive therapies. Some of them are spec...
Source: Techniques in Regional Anesthesia and Pain Management - January 1, 2012 Category: Anesthesiology Authors: Huma U. Sheikh, Paul G. Mathew Source Type: research

Pathophysiology of migraine and tension-type headache
Abstract: Migraine and tension-type headache are common in general population. Recent progress in basic and clinical research has increased our understanding of pathophysiology of these headaches. New treatment modalities and drugs for the treatment of these headaches are emerging. Migraine is a neurovascular headache with complex pathophysiology, which has not been fully clarified. Genes for both migraines, with and without aura, are being identified. Current research indicates importance of cortical spreading depression and abnormal brain stem activity in the pathophysiology of migraine with aura. The migraine headache m...
Source: Techniques in Regional Anesthesia and Pain Management - January 1, 2012 Category: Anesthesiology Authors: Sait Ashina, Lars Bendtsen, Messoud Ashina Source Type: research

The epidemiology and comorbidities of migraine and tension-type headache
Abstract: Headache is one of the most common medical complaints resulting in presentation to a doctor’s office, and it is frequently associated with substantial personal and societal burden. This burden is often greater than the disability associated with several common medical disorders such as hypertension and diabetes. Migraine and tension-type headache (TTH) are the most common primary headache disorders. In the first section of this review, the authors will discuss the incidence and prevalence rates of migraine, as well as the data suggesting that such rates may have increased in the past. This is then followed by a...
Source: Techniques in Regional Anesthesia and Pain Management - January 1, 2012 Category: Anesthesiology Authors: Nu Cindy Chai, Jason D. Rosenberg, B. Lee Peterlin Source Type: research

Introduction: A comprehensive review of primary headache treatments
We present an overview of primary headaches and a wide variety of therapeutic approaches including pharmacologic, interventional, and behavioral. Our purpose with this special issue is to review the scientific evidence for the most commonly performed interventions for the management of acute and chronic headaches. (Source: Techniques in Regional Anesthesia and Pain Management)
Source: Techniques in Regional Anesthesia and Pain Management - January 1, 2012 Category: Anesthesiology Authors: Eli Soto Source Type: research

Big challenges in Pain Medicine: Innovation and comprehensive management our best options at the crossroads
Our understanding of the mechanisms behind the development and maintenance of pain has grown exponentially over the last few decades. Ironically, the field of pain medicine is now under more intense scrutiny than ever. Advocacy for the use of opioids in patients with chronic non-cancer pain may have created a problem of epidemic proportions. Considering the substantial lack of evidence to support the long term use of opioids in this population and the potential for abuse, addiction, tolerance, changes in mental status, osteoporosis, hypogonadism, increased risk of CAD, respiratory depression, and constipation, the liberal ...
Source: Techniques in Regional Anesthesia and Pain Management - January 1, 2012 Category: Anesthesiology Authors: Ricardo Vallejo Source Type: research

Table of Contents
(Source: Techniques in Regional Anesthesia and Pain Management)
Source: Techniques in Regional Anesthesia and Pain Management - January 1, 2012 Category: Anesthesiology Source Type: research

Editorial Board
(Source: Techniques in Regional Anesthesia and Pain Management)
Source: Techniques in Regional Anesthesia and Pain Management - January 1, 2012 Category: Anesthesiology Source Type: research