Albumin--Beyond Fluid Replacement in Cardiopulmonary Bypass Surgery: Why, How, and When?
Maintaining vascular barrier competence, preventing interstitial edema, and keeping microcirculation intact is crucial to achieve an optimal outcome in cardiopulmonary bypass surgery (CPB). Blood contact with roller pumps and foreign surfaces during CPB induces shear stress and a pressure drop across the pump boot that leads to transient systemic activation of the inflammatory and hemostatic systems. Moreover, patients after CPB often need volume resuscitation using the smallest possible amount of colloid solution because of fluid overload. For this purpose, human-derived albumin may be preferred over synthetic colloids be...
Source: Seminars in Cardiothoracic and Vascular Anesthesia - August 7, 2014 Category: Anesthesiology Authors: Moret, E., Jacob, M. W., Ranucci, M., Schramko, A. A. Tags: Reviews Source Type: research

Response to "Aortic Coarctation Complicated by Aortoesophageal Fistula: Fortune Is Blind!"
(Source: Seminars in Cardiothoracic and Vascular Anesthesia)
Source: Seminars in Cardiothoracic and Vascular Anesthesia - August 7, 2014 Category: Anesthesiology Authors: Ing, R. J., Merritt, G. R., Krieves, M. A., Bruny, J. L. Tags: Response from Authors Source Type: research

Aortic Coarctation Complicated by Aortoesophageal Fistula: Fortune Is Blind!
(Source: Seminars in Cardiothoracic and Vascular Anesthesia)
Source: Seminars in Cardiothoracic and Vascular Anesthesia - August 7, 2014 Category: Anesthesiology Authors: Bozzani, A., Arici, V., Lovotti, M., Ragni, F. Tags: Letter to the Editor Source Type: research

About Dogs, Mice, and Men: From Ischemic Preconditioning to Anesthetic Postconditioning of the Heart
(Source: Seminars in Cardiothoracic and Vascular Anesthesia)
Source: Seminars in Cardiothoracic and Vascular Anesthesia - August 7, 2014 Category: Anesthesiology Authors: Eckle, T. Tags: Guest Editorial Source Type: research

From Marfan's Syndrome to Double Outlet Right Ventricle--And Everything in Between
(Source: Seminars in Cardiothoracic and Vascular Anesthesia)
Source: Seminars in Cardiothoracic and Vascular Anesthesia - August 7, 2014 Category: Anesthesiology Authors: Weitzel, N. S. Tags: Editorial Source Type: research

Cardiac Calendar 2014-2020
(Source: Seminars in Cardiothoracic and Vascular Anesthesia)
Source: Seminars in Cardiothoracic and Vascular Anesthesia - May 29, 2014 Category: Anesthesiology Tags: Cardiac Calendar 2014-2020 Source Type: research

Perioperative Diastolic Dysfunction: A Comprehensive Approach to Assessment by Transesophageal Echocardiography
Left ventricular diastolic dysfunction (LVDD) has only recently been recognized as an important determinant of perioperative morbidity. Intraoperative echocardiographers have been slow to adopt assessment of LVDD into clinical practice. This has been partly attributable to the complex measurements required to characterize LVDD, which are in turn related to how our understanding of diastole has evolved. Additionally, the lack of effective therapeutic options has left many wondering whether it is worthwhile to characterize this pathology in the first place. However, therapies are developed more rapidly once a problem can be ...
Source: Seminars in Cardiothoracic and Vascular Anesthesia - May 29, 2014 Category: Anesthesiology Authors: Nicoara, A., Whitener, G., Swaminathan, M. Tags: Reviews Source Type: research

New Insights Into Diastolic Dysfunction and Heart Failure With Preserved Ejection Fraction
As the population ages, the incidence of patients presenting for surgical procedures with diastolic dysfunction and heart failure with preserved ejection fraction will rise. This review will discuss the most current and relevant information on the pathophysiology, treatment, and perioperative management of these patients. (Source: Seminars in Cardiothoracic and Vascular Anesthesia)
Source: Seminars in Cardiothoracic and Vascular Anesthesia - May 29, 2014 Category: Anesthesiology Authors: Gelzinis, T. A. Tags: Reviews Source Type: research

Overcoming Challenges in the Management of Critical Events During Cardiopulmonary Bypass
Critical events during cardiopulmonary bypass (CPB) can challenge the most experienced perfusionists, anesthesiologists, and surgeons and can potentially lead to devastating outcomes. Much of the challenge of troubleshooting these events requires a key understanding of these situations and a well-defined strategy for early recognition and treatment. Adverse situations may be anticipated prior to going on CPB. Atherosclerosis is pervasive, and a high plaque burden may have implications in surgical technique modification and planning of CPB. Hematologic abnormalities such as cold agglutinins, antithrombin III deficiency, and...
Source: Seminars in Cardiothoracic and Vascular Anesthesia - May 29, 2014 Category: Anesthesiology Authors: Mukherji, J., Hood, R. R., Edelstein, S. B. Tags: Reviews Source Type: research

A 2014 Update on Coagulation Management for Cardiopulmonary Bypass
Coagulopathy after cardiac surgery with cardiopulmonary bypass is a serious complication that may result in massive bleeding requiring transfusion of significant amounts of blood products, plasma, and platelets. In addition to increased patient morbidity and mortality it is associated with longer hospital stay and increased resource utilization. The current review discusses aspects in cardiopulmonary bypass–induced coagulopathy with emphasis on point-of-care testing and individualized "goal-directed" therapy in patients who develop excessive bleeding after cardiac surgery. (Source: Seminars in Cardiothoracic and Vascular Anesthesia)
Source: Seminars in Cardiothoracic and Vascular Anesthesia - May 29, 2014 Category: Anesthesiology Authors: Thiele, R. H., Raphael, J. Tags: Reviews Source Type: research

Pathophysiology of Cardiopulmonary Bypass: Current Strategies for the Prevention and Treatment of Anemia, Coagulopathy, and Organ Dysfunction
The techniques and equipment of cardiopulmonary bypass (CPB) have evolved over the past 60 years, and numerous numbers of cardiac surgical procedures are conducted around the world using CPB. Despite more widespread applications of percutaneous coronary and valvular interventions, the need for cardiac surgery using CPB remains the standard approach for certain cardiac pathologies because some patients are ineligible for percutaneous procedures, or such procedures are unsuccessful in some. The ageing patient population for cardiac surgery poses a number of clinical challenges, including anemia, decreased cardiopulmonary res...
Source: Seminars in Cardiothoracic and Vascular Anesthesia - May 29, 2014 Category: Anesthesiology Authors: Esper, S. A., Subramaniam, K., Tanaka, K. A. Tags: Reviews Source Type: research

Recent Advances in Pediatric Cardiopulmonary Bypass
There have been numerous recent advances geared specifically toward the practice of pediatric cardiopulmonary bypass (CPB). These advances include the development of the first oxygenator intended solely for the neonatal CPB patient; pediatric oxygenators with low prime volumes and surface areas, which allow flows up to 2 L/min; pediatric oxygenators with integrated arterial filters; and miniature ultrafiltration (UF) devices, which allow for high rates of ultrafiltrate removal. When used in combination with heart lung machines with mast-mounted pumps, these advances can result in significant decreases in CPB circuit surfac...
Source: Seminars in Cardiothoracic and Vascular Anesthesia - May 29, 2014 Category: Anesthesiology Authors: McRobb, C. M., Mejak, B. L., Ellis, W. C., Lawson, D. S., Twite, M. D. Tags: Reviews Source Type: research

Advances in Perfusion Techniques: Minimally Invasive Procedures
There is a growing demand from patients and referring physicians for minimally invasive cardiac surgery. Minimally invasive cardiac procedures are technically unique from conventional cardiac procedures and require a thorough understanding of the surgical, anesthetic, and perfusion strategies. Strategies include routine use of augmented venous drainage, alternative arterial and venous cannulation sites, and special cannulas designed for minimally invasive procedures. The following review describes the strategies and safety systems that should be considered when performing minimally invasive cardiac surgery. (Source: Semina...
Source: Seminars in Cardiothoracic and Vascular Anesthesia - May 29, 2014 Category: Anesthesiology Authors: Shann, K., Melnitchouk, S. Tags: Reviews Source Type: research

Aortic Surgery and Deep-Hypothermic Circulatory Arrest: Anesthetic Update
This article summarizes the anesthetic considerations for procedures on the aortic arch, including evidence-based outcomes with respect to temperature management, perfusion strategies, hemodynamic goals, adjunct agents, and neuromonitoring. (Source: Seminars in Cardiothoracic and Vascular Anesthesia)
Source: Seminars in Cardiothoracic and Vascular Anesthesia - May 29, 2014 Category: Anesthesiology Authors: Reed, H., Berg, K. B., Janelle, G. M. Tags: Reviews Source Type: research

Perioperative Maintenance of Tissue Perfusion and Cardiac Output in Cardiac Surgery Patients
(Source: Seminars in Cardiothoracic and Vascular Anesthesia)
Source: Seminars in Cardiothoracic and Vascular Anesthesia - May 29, 2014 Category: Anesthesiology Authors: Lighthall, G. K., Singh, S. Tags: Reviews Source Type: research