Longitudinal Echocardiographic Evaluation of an Unusual Presentation of X-Linked Myxomatous Valvular Dystrophy Caused by Filamin A Mutation
We present a patient with significant echocardiographic findings of mitral and tricuspid valvar regurgitation, aortic dilatation, and intraoperative findings of aortic ectasia. In our case, a detailed family history led to a preoperative echocardiogram revealing myxomatous mitral and tricuspid valve degeneration with significant regurgitation and aortic dilatation. Genetic evaluation led to the diagnosis of a Filamin A mutation. Pre- and postrepair echocardiographic assessments of valvar function played a key role in the management of this patient. Continued surveillance of his aortic dilation and evaluation of postrepair ...
Source: Seminars in Cardiothoracic and Vascular Anesthesia - July 18, 2016 Category: Anesthesiology Authors: Ma, P. H., Sachdeva, R., Wilson, E. C., Guzzetta, N. A. Tags: Case Report Source Type: research

Echocardiographic Discovery of Doubled Interatrial Septum: An Incidental Finding
A double-walled interatrial septum is a rare congenital cardiac anomaly characterized by a distinct echolucent cavity between the atria formed by 2 separate interatrial septae. It may be a variant of other well-recognized cardiac anomalies such as persistent venous valve of the sinus venosus or cor triatriatum. Although uncommon, it may be associated with thromboembolic disease due to stagnant flow in the septal cavity. Awareness of this rare entity and its clinical significance along with a thorough echocardiographic examination to rule out similarly presenting or coexisting conditions are the key to an accurate diagnosis...
Source: Seminars in Cardiothoracic and Vascular Anesthesia - July 18, 2016 Category: Anesthesiology Authors: Kumar, P. A., Martinelli, S. M., Kyle, R. W., Arora, H. Tags: Clinical Challenges Source Type: research

Anomalous Coronary Artery: Run of a Lifetime
The anatomy of the coronary circulation is well described with incidence of congenital anomalies of approximately 0.3% to 1.0%. Although often incidental, 20% are life-threatening. A 25-year-old woman with syncopal episodes collapsed following a 10-km run. Coronary anatomy evaluation showed an anomalous left main coronary artery originating from the right sinus of valsalva and following a course between the aorta and the pulmonary outflow tract. Percutaneous coronary intervention was followed by eventual surgical revascularization. Abnormal course of coronary arteries plays a role in the pathogenesis of sudden death on exe...
Source: Seminars in Cardiothoracic and Vascular Anesthesia - July 18, 2016 Category: Anesthesiology Authors: Green, M. S., Sehgal, S., Smukler, N., Suber, L. J., Saththasivam, P. Tags: Clinical Challenges Source Type: research

Intraoperative Embolization and Cognitive Decline After Cardiac Surgery: A Systematic Review
Since the advent of cardiac surgery, complications have existed in many forms. Recent work has focused on the safety of current cardiac surgery with particular emphasis on cognitive outcomes. Cardiopulmonary bypass has improved the safety of operative practice; however, increasing concern surrounds the measurable and immeasurable impact embolization has on the brain. New ischemic lesions have been associated with distant emboli, which intraoperatively enter the cardiovascular system. This has prompted better characterization of the nature of emboli manifesting as cognitive impairment postoperatively. The difficulty in attr...
Source: Seminars in Cardiothoracic and Vascular Anesthesia - July 18, 2016 Category: Anesthesiology Authors: Patel, N., Minhas, J. S., Chung, E. M. L. Tags: Reviews Source Type: research

Near-Infrared Spectroscopy: The New Must Have Tool in the Intensive Care Unit?
Standard hemodynamic monitoring such as blood pressure and pulse oximetry may only provide a crude estimation of organ perfusion in the critical care setting. Near-infrared spectroscopy (NIRS) is based on the same principle as a pulse oximeter and allows continuous noninvasive monitoring of hemoglobin oxygenation and deoxygenation and thus tissue saturation "StO2." This review aims to provide an overview of NIRS technology principles and discuss its current clinical use in the critical care setting. The study selection was performed using the PubMed database to find studies that investigated the use of NIRS in both the cri...
Source: Seminars in Cardiothoracic and Vascular Anesthesia - July 18, 2016 Category: Anesthesiology Authors: Green, M. S., Sehgal, S., Tariq, R. Tags: Reviews Source Type: research

Effects of Parasternal Block on Acute and Chronic Pain in Patients Undergoing Coronary Artery Surgery
Conclusion. Parasternal block had a benefical effect on the management of postoperative acute pain and decreased opioid consumption after surgery but had no significant effect in chronic post surgical pain. (Source: Seminars in Cardiothoracic and Vascular Anesthesia)
Source: Seminars in Cardiothoracic and Vascular Anesthesia - July 18, 2016 Category: Anesthesiology Authors: Dogan Bakı, E., Kavrut Ozturk, N., Ayoglu, R. U., Emmiler, M., Karslı, B., Uzel, H. Tags: Original Research Source Type: research

Trends in the Management of Patients With Left Ventricular Assist Devices Presenting for Noncardiac Surgery: A 10-Year Institutional Experience
In our institution, the vast majority of patients presenting for noncardiac surgery (NCS) while supported by a left ventricular assist device (LVAD) are now cared for by noncardiac-trained anesthesiologists as the result of a decade of educational intervention to effect this transition. This represents a significant departure from the published experiences of other institutions. With institutional review board approval, we queried the database of our anesthesia record keeping system (CompuRecord) to determine various aspects of the perioperative management of these patients from July 1, 2003, through June 30, 2013, during ...
Source: Seminars in Cardiothoracic and Vascular Anesthesia - July 18, 2016 Category: Anesthesiology Authors: Stone, M., Hinchey, J., Sattler, C., Evans, A. Tags: Original Research Source Type: research

Multiparameter Predictor of Fluid Responsiveness in Cardiac Surgical Patients Receiving Tidal Volumes Less Than 10 mL/kg
Conclusion. While integration of multiple physiologic waveforms as well as ventilator parameters improves the predictability of fluid responsive metrics in the setting of lung-protective ventilation, the composite index may still be of limited predictive value. (Source: Seminars in Cardiothoracic and Vascular Anesthesia)
Source: Seminars in Cardiothoracic and Vascular Anesthesia - July 18, 2016 Category: Anesthesiology Authors: Ikeda, K., Smith, G., Renehan, J., Isbell, J., McMurry, T., Rosner, M., Thiele, R. Tags: Original Research Source Type: research

Meet the Demand: Challenges of Practicing Cardiac Anesthesiology
(Source: Seminars in Cardiothoracic and Vascular Anesthesia)
Source: Seminars in Cardiothoracic and Vascular Anesthesia - July 18, 2016 Category: Anesthesiology Authors: Kertai, M. D. Tags: Editorial Source Type: research

Cardiac Calendar 2016-2020
(Source: Seminars in Cardiothoracic and Vascular Anesthesia)
Source: Seminars in Cardiothoracic and Vascular Anesthesia - May 3, 2016 Category: Anesthesiology Tags: Cardiac Calendar 2016-2020 Source Type: research

Cardiac Arrest in a Heart Transplant Patient Receiving Dexmedetomidine During Cardiac Catheterization
We present such a patient who had a cardiac arrest while receiving dexmedetomidine during cardiac catheterization. Because acute cellular rejection of the cardiac conduction system is difficult to diagnose, dexmedetomidine should be used with caution in pediatric heart transplant patients. (Source: Seminars in Cardiothoracic and Vascular Anesthesia)
Source: Seminars in Cardiothoracic and Vascular Anesthesia - May 3, 2016 Category: Anesthesiology Authors: Schwartz, L. I., Miyamoto, S. D., Stenquist, S., Twite, M. D. Tags: Congenital Forum Source Type: research

Challenging Argatroban Management of a Child on Extracorporeal Support and Subsequent Heart Transplant
A 6-year-old child developed heparin-induced thrombocytopenia while on extracorporeal life support. Hours after a difficult transition from heparin to argatroban for anticoagulation therapy, the child underwent heart transplantation. Intraoperative management was plagued with circuit thrombus formation while on cardiopulmonary bypass and subsequent massive hemorrhage after bypass. We review the child’s anticoagulation management, clinical challenges encountered, and review current literature related to the use of argatroban in pediatric cardiac surgery. (Source: Seminars in Cardiothoracic and Vascular Anesthesia)
Source: Seminars in Cardiothoracic and Vascular Anesthesia - May 3, 2016 Category: Anesthesiology Authors: Latham, G. J., Jefferis Kirk, C., Falconer, A., Dickey, R., Albers, E. L., McMullan, D. M. Tags: Congenital Forum Source Type: research

Quadruple Vessel Coronary Artery Bypass Grafting in a 14-Year-Old Child With Plasminogen Activator Inhibitor-1 4G/4G Gene Polymorphism
We present the case of a 14-year-old boy who underwent quadruple-vessel coronary artery bypass grafting with bilateral pedicled internal mammary artery and bilateral radial artery grafting. We try to highlight a rare but important 4G variant PAI-1 (SERPINE 1) gene mutation as the etiology of severe coronary artery disease in our patient. To the best of our knowledge, he is one of the youngest patients who underwent coronary artery bypass surgery with 4 arterial grafts. (Source: Seminars in Cardiothoracic and Vascular Anesthesia)
Source: Seminars in Cardiothoracic and Vascular Anesthesia - May 3, 2016 Category: Anesthesiology Authors: Cvetkovic, D., Lafaro, R., Giamelli, J., Suvro, S., Erb, M., Yaghoubian, S. Tags: Congenital Forum Source Type: research

Transfemoral Transcatheter Aortic Valve Replacement for Mixed Aortic Valve Disease in Childs Class C Liver Disease Prior to Orthotopic Liver Transplantation: A Case Report
We report our experience of liver transplantation in a patient with severe aortic stenosis and moderate aortic insufficiency who underwent transcatheter aortic valve replacement with Child-Pugh Class C disease at a Model For End-Stage Liver Disease score of 29. The patient had a difficult post procedure course that was successfully medically managed. After liver transplantation the patient was discharged to home on postoperative day 11. The combination of cardiac disease and end stage liver disease is challenging but these patients can have a successful outcome despite very severe illness. (Source: Seminars in Cardiothorac...
Source: Seminars in Cardiothoracic and Vascular Anesthesia - May 3, 2016 Category: Anesthesiology Authors: Wilkey, B. J., Hanson, R., Reece, T. B., Forman, L., Burton, J. R., Messenger, J. C., Kim, M. S., Cleveland, J. C., Fiegel, M. J., Nydam, T. L., Mandell, M. S. Tags: Clinical Challenges Source Type: research

A Practical Approach to Managing Transcatheter Aortic Valve Replacement With Sedation
We describe an anesthetic protocol that avoids general anesthesia and utilizes transthoracic echocardiography for procedural guidance. (Source: Seminars in Cardiothoracic and Vascular Anesthesia)
Source: Seminars in Cardiothoracic and Vascular Anesthesia - May 3, 2016 Category: Anesthesiology Authors: Neuburger, P. J., Saric, M., Huang, C., Williams, M. R. Tags: Reviews Source Type: research