Cardiac Calendar 2014-2020
(Source: Seminars in Cardiothoracic and Vascular Anesthesia)
Source: Seminars in Cardiothoracic and Vascular Anesthesia - October 28, 2014 Category: Anesthesiology Tags: Cardiac Calendar 2014-2020 Source Type: research

Successful One-Lung Ventilation in a Patient With the Fontan Circulation Undergoing Thoracoscopic Procedure
We present a case of successful one-lung ventilation in a patient with the Fontan circulation and describe the perioperative anesthetic management. (Source: Seminars in Cardiothoracic and Vascular Anesthesia)
Source: Seminars in Cardiothoracic and Vascular Anesthesia - October 28, 2014 Category: Anesthesiology Authors: Cvetkovic, D., Ramzy, W., Vitale, S., Malekan, R., Warsy, I. Tags: Clinical Challenge Source Type: research

Anesthetic Dilemmas for Dynamic Evaluation of the Pediatric Upper Airway
Sleep cine magnetic resonance imaging and drug-induced sleep endoscopy are currently used to examine the patterns of dynamic airway collapse in children with obstructive sleep apnea. Providing anesthesia that mimics physiologic sleep in these children is a challenge but is critical for accurate interpretation of the airway evaluation. Anesthetic agents might negatively affect the upper airway evaluation. The anesthetic technique in these patients must be tailored to improve patient safety and obtain optimal study. This review focuses on the periprocedural challenges and anesthetic management of children presenting for dyna...
Source: Seminars in Cardiothoracic and Vascular Anesthesia - October 28, 2014 Category: Anesthesiology Authors: Chatterjee, D., Friedman, N., Shott, S., Mahmoud, M. Tags: Congenital Cardiac Forum Source Type: research

Anesthetic Drugs in Congenital Heart Disease
The structural defects associated with the various forms of congenital heart disease lead to pathological and functional changes that place patients at risk for adverse events, and in fact the perioperative incidence of morbidity and mortality has been documented to be increased in children with congenital heart disease. Patients with congenital heart disease can present to the anesthesiologist in a relatively precarious state of balance of several hemodynamic factors, including preload, ventricular contractility, systemic vascular resistance, pulmonary vascular resistance, heart rate, and cardiac rhythm. Anesthetic drugs ...
Source: Seminars in Cardiothoracic and Vascular Anesthesia - October 28, 2014 Category: Anesthesiology Authors: Friesen, R. H. Tags: Congenital Cardiac Forum Source Type: research

Endpoints of Resuscitation: What Are They Anyway?
Hemodynamic optimization of surgical patients during and after surgery in the Surgical Intensive Care Unit is meant to improve outcomes. These outcomes have been measured by Length Of Stay (LOS), rate of infection, days on ventilator, etc. Unfortunately, the adaptation of modern technology to accomplish this has been slow in coming. Ever since Shoemaker described in 1988 using a pulmonary artery catheter (PAC) to guide fluid and inotropic administration to deliver supranormal tissue oxygenation, many authors have written about different techniques to achieve this "hemodynamic optimization". Since the PAC and CVC have both ...
Source: Seminars in Cardiothoracic and Vascular Anesthesia - October 28, 2014 Category: Anesthesiology Authors: Tseng, G. S., Wall, M. H. Tags: General Review Source Type: research

Update on Perioperative Right Heart Assessment Using Transesophageal Echocardiography
Purpose of the review. This review aims to summarize recent findings relevant for perioperative 2- and 3-dimensional imaging of the right heart with transesophageal echocardiography. Special attention is given to developments that are likely to affect future approaches for prevention and therapy of perioperative right heart failure. Recent findings. Three-dimensional transesophageal echocardiography techniques are becoming more common for the evaluation of anatomy, volumes, and functional indices. Summary. Right heart failure continues to contribute to morbidity and mortality in the context of cardiothoracic surgery. The a...
Source: Seminars in Cardiothoracic and Vascular Anesthesia - October 28, 2014 Category: Anesthesiology Authors: Bartels, K., Karhausen, J., Sullivan, B. L., Mackensen, G. B. Tags: Focus Section: Right Sided Disease Source Type: research

Pulmonary Endarterectomy: Part II. Operation, Anesthetic Management, and Postoperative Care
Chronic thromboembolic pulmonary hypertension (CTEPH) results from recurrent or incomplete resolution of pulmonary embolism. CTEPH is much more common than generally appreciated. Although pulmonary embolism (PE) affects a large number of Americans, chronic pulmonary thromboembolic hypertension remains underdiagnosed. It is imperative that all patients with pulmonary hypertension (PH) be screened for the presence of CTEPH since this form of PH is potentially curable with pulmonary endarterectomy (PEA) surgery. The success of this procedure depends greatly on the collaboration of a multidisciplinary team approach that includ...
Source: Seminars in Cardiothoracic and Vascular Anesthesia - October 28, 2014 Category: Anesthesiology Authors: Banks, D. A., Pretorius, G. V. D., Kerr, K. M., Manecke, G. R. Tags: Focus Section: Right Sided Disease Source Type: research

Pulmonary Endarterectomy: Part I. Pathophysiology, Clinical Manifestations, and Diagnostic Evaluation of Chronic Thromboembolic Pulmonary Hypertension
Chronic thromboembolic pulmonary hypertension (CTEPH) results from recurrent or incomplete resolution of pulmonary embolism. CTEPH is much more common than generally appreciated. Although pulmonary embolism (PE) affects a large number of Americans, chronic pulmonary hypertension (PH) remains underdiagnosed. It is imperative that all patients with PH be screened for the presence of CTEPH since this form of PH is potentially curable with pulmonary thromboendarterectomy (PTE) surgery. The success of this procedure depends greatly on the collaboration of a multidisciplinary team approach that includes pulmonary medicine, cardi...
Source: Seminars in Cardiothoracic and Vascular Anesthesia - October 28, 2014 Category: Anesthesiology Authors: Banks, D. A., Pretorius, G. V. D., Kerr, K. M., Manecke, G. R. Tags: Focus Section: Right Sided Disease Source Type: research

Perioperative Management of the Patient With Pulmonary Hypertension
Patients with pulmonary hypertension are at increased risk for perioperative morbidity and mortality. Elective surgery is generally discouraged in this patient population; however, there are times when surgery is deemed necessary. Currently, there are no guidelines for the preoperative risk assessment or perioperative management of subjects with pulmonary hypertension. The majority of the literature evaluating perioperative risk factors and mortality rates is observational and includes subjects with multiple etiologies of pulmonary hypertension. Subjects with pulmonary arterial hypertension, also referred to as World Healt...
Source: Seminars in Cardiothoracic and Vascular Anesthesia - October 28, 2014 Category: Anesthesiology Authors: Fox, D. L., Stream, A. R., Bull, T. Tags: Focus Section: Right Sided Disease Source Type: research

A Focus on Right-Sided Cardiac Disease
(Source: Seminars in Cardiothoracic and Vascular Anesthesia)
Source: Seminars in Cardiothoracic and Vascular Anesthesia - October 28, 2014 Category: Anesthesiology Authors: Weitzel, N. S. Tags: Editorial Source Type: research

Hemophilia C in a Patient Undergoing Cardiac Surgery: Perioperative Considerations
(Source: Seminars in Cardiothoracic and Vascular Anesthesia)
Source: Seminars in Cardiothoracic and Vascular Anesthesia - August 7, 2014 Category: Anesthesiology Authors: Leff, J. D., Zumberg, M. S., Widyn, J. G., DeAnda, A., Janelle, G. M. Tags: Roundtable Discussion Source Type: research

Efficacy of Evolving Early-Extubation Strategy on Early Postoperative Functional Recovery in Pediatric Open-Heart Surgery: A Matched Case-Control Study
We examined 50 consecutive pediatric cardiac surgery patients extubated in the operating room (February 2009 to July 2009) against a control group of delayed-extubation patients. No significant differences were found in preoperative variables except heart failure medication. Significant intraoperative variables included the following: blood products (363 vs 487 mL, P = .023), morphine (62% vs 6%, P < .0001), and inotropes (16% vs 60%, P < .0001) given. Postoperatively significant differences included hospital stay and lower inotrope scores in the early-extubation group (14.89 vs 31.68, P < .0001). The reintubation...
Source: Seminars in Cardiothoracic and Vascular Anesthesia - August 7, 2014 Category: Anesthesiology Authors: Hamilton, B. C. S., Honjo, O., Alghamdi, A. A., Caldarone, C. A., Schwartz, S. M., Van Arsdell, G. S., Holtby, H. Tags: Original Research Source Type: research

Perioperative Management of DORV
The diagnosis of double-outlet right ventricle (DORV) characterizes a complex heterogeneous group of congenital cardiac malformations for which multiple classification schemes have been used. A clear understanding of the anatomy is critical to understanding the physiologic consequences of the specific type of DORV. Perioperative considerations include the medical management of the patient during the preoperative period, anesthetic and surgical management, and postoperative care. Both anesthetic and surgical management strategies are very different depending on the type of DORV. Key principles for anesthetic management incl...
Source: Seminars in Cardiothoracic and Vascular Anesthesia - August 7, 2014 Category: Anesthesiology Authors: Spaeth, J. P. Tags: Congenital Cardiac Forum Source Type: research

The Role of Cyclooxygenase-1 and -2 in Sevoflurane-Induced Postconditioning Against Myocardial Infarction
Cyclooxygenase (COX)-2 mediates ischemic pre- and postconditioning as well as anesthetic-induced preconditioning. However, the role of COX-1 and -2 in anesthetic-induced postconditioning has not been investigated. We evaluated the role of COX-1 and -2 in sevoflurane-induced postconditioning in vivo. Pentobarbital-anaesthetized male C57BL/6 mice were subjected to 45 minutes of coronary artery occlusion and 3 hours of reperfusion. Animals received either no intervention, the vehicle dimethyl sulfoxide (DMSO, 10 µL/g intraperitoneally), acetylsalicylic acid (ASA, 5 µg/g intraperitoneally), the selective COX-1 inhi...
Source: Seminars in Cardiothoracic and Vascular Anesthesia - August 7, 2014 Category: Anesthesiology Authors: Stumpner, J., Tischer-Zeitz, T., Frank, A., Lotz, C., Redel, A., Lange, M., Kehl, F., Roewer, N., Smul, T. Tags: Original Research Source Type: research

Marfan Syndrome: Clinical, Surgical, and Anesthetic Considerations
Marfan syndrome is a multisystem connective tissue disorder, with primary involvement of the cardiovascular, ocular, and skeletal systems. This autosomal heritable disease is mainly attributable to a defect in the FBN1 gene. Clinical diagnosis of Marfan syndrome has been based on the Ghent criteria since 1996. In 2010, these criteria were updated, and the revised guidelines place more emphasis on aortic root dilation, ectopia lentis, and FBN1 mutation testing in the diagnostic assessment of Marfan syndrome. Among its many different clinical manifestations, cardiovascular involvement deserves special consideration, owing to...
Source: Seminars in Cardiothoracic and Vascular Anesthesia - August 7, 2014 Category: Anesthesiology Authors: Castellano, J. M., Silvay, G., Castillo, J. G. Tags: Reviews Source Type: research