Roumanian Archives of Microbiology and Immunology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

In Memoriam: Dr Geza Adalbert SZEGLI (17 January 1929-25 December 2014).
Authors: PMID: 26727848 [PubMed - in process] (Source: Roumanian Archives of Microbiology and Immunology)
Source: Roumanian Archives of Microbiology and Immunology - January 14, 2016 Category: Microbiology Tags: Roum Arch Microbiol Immunol Source Type: research

Screening of protease inhibitors resistance mutations in hepatitis c virus isolates infecting romanian patients unexposed to triple therapy.
SCREENING OF PROTEASE INHIBITORS RESISTANCE MUTATIONS IN HEPATITIS C VIRUS ISOLATES INFECTING ROMANIAN PATIENTS UNEXPOSED TO TRIPLE THERAPY. Roum Arch Microbiol Immunol. 2015 Jan-Jun;74(1-2):7-17 Authors: Dinu S, Calistru PI, Ceauşu E, Târdeil G, Oprişan G Abstract Although the European recommendations include the use of new antiviral drugs for the treatment of hepatitis C, in Romania the current treatment remains interferon plus ribavirin. First generation viral protease inhibitors (i.e. boceprevir, telaprevir), which have raised the chances of obtaining viral clearance in up ...
Source: Roumanian Archives of Microbiology and Immunology - January 14, 2016 Category: Microbiology Tags: Roum Arch Microbiol Immunol Source Type: research

Genomic analysis of hepatitis b virus strains infecting romanian patients.
This study was designed to improve the national laboratory surveillance of hepatitis B virus (HBV) infection, focusing on genomic analysis of isolates from Romanian patients. Sera from ten patients with HBV were collected and analyzed. Phylogenetic analysis was conducted on a DNA fragment spanning almost the entire genome. The occurrence of mutations was assessed for each open reading frame in the viral genome. Phylogenetic analysis revealed five isolates belonging to genotype A (subgenotype A2) and other five clustering with genotype D strains (subgenotype D1). Two patients treated with lamivudine were found to carry isol...
Source: Roumanian Archives of Microbiology and Immunology - January 14, 2016 Category: Microbiology Tags: Roum Arch Microbiol Immunol Source Type: research

Antimicrobial resistance and genetic diversity of shigella sonnei isolates from romania.
ANTIMICROBIAL RESISTANCE AND GENETIC DIVERSITY OF SHIGELLA SONNEI ISOLATES FROM ROMANIA. Roum Arch Microbiol Immunol. 2015 Jan-Jun;74(1-2):26-32 Authors: Cristea D, Oprea M, Ciontea AS, Usein CR Abstract Although not endemic in the European Union and European Economic Area, shigellosis is included among the priority food- and waterborne diseases carefully surveyed by the European Centre for Disease Prevention and Control. From 2010 to 2012, 1018 cumulated confirmed shigellosis cases were reported to the European Surveillance System by Romania. This retrospective study aimed to pro...
Source: Roumanian Archives of Microbiology and Immunology - January 14, 2016 Category: Microbiology Tags: Roum Arch Microbiol Immunol Source Type: research

E5HPV16 mRNA EXPRESSION PATTERN ANALYSIS IN PATIENTS WITH CERVICAL LESIONS IN VIRAL STATUS CONTEXT.
Authors: Iancu IV, Pleşa A, Botezatu A, Huică I, Stănescu AD, Socolov D, Anton G Abstract Human papilloma virus (HPV) may cause mostly transient infections of cutaneous and mucous epithelia. Persistent HPV genital infections may induce pre-malignant or malignant lesions. While E6 and E7 HPV genes' malignant character is known, E5 is still under debate. We evaluated the possible role of E5 gene in cervix oncogenesis, in patients with abnormal cytology and HPV1 6 positive, in the context of viral status correlated with potential targets (p21, EGFR). HPV DNA was detected and genotyped using Linear Array HP...
Source: Roumanian Archives of Microbiology and Immunology - January 14, 2016 Category: Microbiology Tags: Roum Arch Microbiol Immunol Source Type: research

The performance of a rapid test for anti-hcv screening in oral fluids.
CONCLUSIONS: Oral fluids could be an alternative to blood for detection of HCV-positive subjects. Anti-HCV rapid test may be useful in routine dental medicine. PMID: 26727853 [PubMed - in process] (Source: Roumanian Archives of Microbiology and Immunology)
Source: Roumanian Archives of Microbiology and Immunology - January 14, 2016 Category: Microbiology Tags: Roum Arch Microbiol Immunol Source Type: research

Host-pathogen interaction in infections due to staphylococcus aureus. staphylococcus aureus virulence factors.
HOST-PATHOGEN INTERACTION IN INFECTIONS DUE TO STAPHYLOCOCCUS AUREUS. STAPHYLOCOCCUS AUREUS VIRULENCE FACTORS. Roum Arch Microbiol Immunol. 2015 Jan-Jun;74(1-2):46-64 Authors: Drăgulescu EC, Codiţă I Abstract Staphylococcus aureus (S. aureus) is a major cause of hospital-acquired (HA-SA) and community-acquired (CA-SA) infections worldwide. It is isolated from many human body sites, from animals and from foods, from the environment. Pathogenesis is caused by many virulence factors and antibiotic resistance. The host immune system tries to keep under control this pathogen, but ma...
Source: Roumanian Archives of Microbiology and Immunology - January 14, 2016 Category: Microbiology Tags: Roum Arch Microbiol Immunol Source Type: research

Rapid communication-- polio vaccine coverage in the acute flaccid paralysis (afp) cases in romania.
RAPID COMMUNICATION-- POLIO VACCINE COVERAGE IN THE ACUTE FLACCID PARALYSIS (AFP) CASES IN ROMANIA. Roum Arch Microbiol Immunol. 2015 Jan-Jun;74(1-2):65-7 Authors: Băicuş A Abstract Poliovirus (PV), a member of the Enterovirus genus, is the etiological agent of poliomyelitis. A study carried out between 2013-2014 on 30 serum samples from acute flaccid paralysis (AFP) cases, showed a protective antibody level of 90% against poliovirus Sabin strains type 1 and type 2 and of 88% against type 3. No PV strains were isolated from 2009 to 2015 in Romania. Maintaining a high vaccine cov...
Source: Roumanian Archives of Microbiology and Immunology - January 14, 2016 Category: Microbiology Tags: Roum Arch Microbiol Immunol Source Type: research

Phenotypic and molecular methods used for identification of oral streptococci and related microorganisms.
Authors: Damian M, Palade AM, Băltoiu M, Petrini A, Păuna M, Roseanu A Abstract The oral cavity contains the greatest biodiversity, over 70 species being isolated from mouth mucosa, saliva, denture surfaces and/or dental-plaque. The oral streptococci, representing over 80% of the mouth micro flora, are able to synthesize glucosyl-transferases, enzymes involved in glucans production. Glucans are involved in production of an extracellular slime layer promoting adhesion and formation of a dental plaque biofilm. The 43 isolates studied obtained from partially and/or totally edentulous, were identified by VIT...
Source: Roumanian Archives of Microbiology and Immunology - December 12, 2015 Category: Microbiology Tags: Roum Arch Microbiol Immunol Source Type: research

Antimicrobial activity of some new of 2-(4-ethyl-phenoximethyl) benzoic acid thioureides against planktonic cells.
Authors: Drăcea O, Babeş C, Limban C, Delcaru C, Chifiriuc MC, Israil AM Abstract The aim of the present study was to evaluate the antimicrobial activity of new 2-(4-ethyl-phenoxymethyl) benzoic acid thioureides. The synthesis of the new compounds was done in three steps starting with the synthesis of 2-(4-ethyl-phenoxymethyl) benzoic acid. In the second stage, the 2-(4-ethyl-phenoxymethyl)-benzoyl chloride was prepared and the new thioureides were synthesized in the third step by the reaction of 2-(4-ethyl-phenoxymethyl) benzoyl isothiocyanate with various primary aromatic amines. The original compounds...
Source: Roumanian Archives of Microbiology and Immunology - December 12, 2015 Category: Microbiology Tags: Roum Arch Microbiol Immunol Source Type: research

Architecture and physiology of microbial biofilms.
Authors: Lazăr V, Chifiriuc MC Abstract The microbial biofilm, composed by a single or multiple species, is defined as a sessile community of microbial cells irreversibly attached to a substratum or an interface and also among them, embedded in a matrix of extracellular polymeric substances as their own products, exhibiting a modified phenotype concerning the rate of growth and gene transcription. The biofilm is considered a primitive form of cellular differentiation, with primitive circulatory system, homeostasis and "integrality", similar to eukaryotic tissues in their intercellular cooperation. A micro...
Source: Roumanian Archives of Microbiology and Immunology - December 12, 2015 Category: Microbiology Tags: Roum Arch Microbiol Immunol Source Type: research

TGF-beta signalling pathway factors in HPV-induced cervical lesions.
Authors: Iancu IV, Botezatu A, Goia-Ruşanu CD, Stănescu A, Huică I, Nistor E, Anton G, Pleşa A Abstract Human papillomaviruses (HPV) are considered the etiological agents of cervical cancer, especially high-risk genotypes. TGF-beta (transforming growth factor-beta) is well known for its anti-proliferative effects but the neoplastic cells often lose their sensitivity to TGF-beta. A characteristic alteration associated with malignant progression is the loss of responsiveness to TGF-beta1-induced cell growth inhibition. The aim of the present study was to establish the possible role of some members of TGF...
Source: Roumanian Archives of Microbiology and Immunology - December 12, 2015 Category: Microbiology Tags: Roum Arch Microbiol Immunol Source Type: research

Controversies in the laboratory diagnosis of celiac disease in children; new haplotypes discovered.
Authors: Samaşca G, Iancu M, Butnariu A, Pîrvan A, Andreica M, Miu N, Constantinescu I, Dejica D Abstract The latest consensus on celiac disease in 2008, under the auspices of the International Societies of Pediatric Gastroenterology, Hepatology and Nutrition, shows that HLA DQ2/DQ8 typing indicates the highest negative predictive value for celiac disease, which would exclude the diagnosis of celiac disease. In Romania, there are no studies on the implication of HLA-DQ2/DQ8 in celiac disease in children. The aim of our study was to analyze the significance of genetic tests, with a focus on negative HLA-D...
Source: Roumanian Archives of Microbiology and Immunology - December 12, 2015 Category: Microbiology Tags: Roum Arch Microbiol Immunol Source Type: research

Medical significance and new therapeutical strategies for biofilm associated infections.
Authors: Lazăr V, Chifiriuc MC Abstract Recent public announcements stated that 60% to 85% of all microbial infections involve biofilms developed on natural tissues (skin, mucosa, endothelial epithelia, teeth, bones) or artificial devices (central venous, peritoneal and urinary catheters, dental materials, cardiac valves, intrauterine contraceptive devices, contact lenses, different types of implants). Prosthetic medical devices are risk factors of chronic infections in developed countries and these infections are characterized by slow onset, middle intensity symptoms, chronic evolution and resistance to ...
Source: Roumanian Archives of Microbiology and Immunology - December 12, 2015 Category: Microbiology Tags: Roum Arch Microbiol Immunol Source Type: research

The modulation of hela cells secretory patterns by invasive Shigella spp. and enteroinvasive E. coli bacterial cells and their soluble components.
Authors: Chifiriuc MC, Bleotu C, Măruţescu L, Cristea D, Lazăr V Abstract Considering the important role of cytokines in the initiation and evolution of the inflammatory process induced by Shigella and EIEC strains, the purpose of this study was the characterization of the secretory patterns of HeLa cells induced by Shigella ssp. and EIEC strains and to link the obtained results with the invasiveness level of bacterial strains on this cellular line. During this study there were analyzed two EIEC strains and 12 strains of the following Shigella species: 2 Sh. flexneri 2a, 2 Sh. flexneri 3a, 2 Sh. flexner...
Source: Roumanian Archives of Microbiology and Immunology - December 12, 2015 Category: Microbiology Tags: Roum Arch Microbiol Immunol Source Type: research