Comment: “Mapping the scientific research on the negative aspects of the medical school learning environment”
Conclusion: Clinical presentations of UN are broad and non-specific; nonetheless, it is important to detect early changes in order to avoid its progression. The earlier UN is diagnosed and treated, the more successful are the clinical outcomes.RESUMO INTRODU ÇÃO: A neuropatia periférica (NU) é um distúrbio que afeta o corpo celular, o axônio ou a mielina do motor ou neurônios sensoriais periféricos e ocorre em 60%-100% dos pacientes que são submetidos à diálise por doença renal crônica. A neuropatia urêmica é atribuída à acumulação de resíduos orgânicos, evidente em pacientes com taxa de filtração ...
Source: Revista da Associacao Medica Brasileira - March 19, 2019 Category: General Medicine Source Type: research

Uremic neuropathy: an overview of the current literature
Conclusion: Clinical presentations of UN are broad and non-specific; nonetheless, it is important to detect early changes in order to avoid its progression. The earlier UN is diagnosed and treated, the more successful are the clinical outcomes.RESUMO INTRODU ÇÃO: A neuropatia periférica (NU) é um distúrbio que afeta o corpo celular, o axônio ou a mielina do motor ou neurônios sensoriais periféricos e ocorre em 60%-100% dos pacientes que são submetidos à diálise por doença renal crônica. A neuropatia urêmica é atribuída à acumulação de resíduos orgânicos, evidente em pacientes com taxa de filtração ...
Source: Revista da Associacao Medica Brasileira - March 19, 2019 Category: General Medicine Source Type: research

Advances in medical technology and new digital educational platforms
This study was carried out from the review of the scientific literature in PubMed and SciELO databases. Complete exclusion of conventional dairy products is not necessary since most individuals with LI can tolerate up to 12 grams of lactose daily in a single dose. Yogurts and cheeses matured for having low amounts of lactose are part of the strategy that allows consumption of dairy products by patients with LI. Currently, there is a diversity of products considered as “ milk substitutes ” and supplements aimed at individuals with LI. However, these strategies still require better-designed studies.RESUMO Os indiv íduo...
Source: Revista da Associacao Medica Brasileira - March 19, 2019 Category: General Medicine Source Type: research

Lactose intolerance: what is a correct management?
This study was carried out from the review of the scientific literature in PubMed and SciELO databases. Complete exclusion of conventional dairy products is not necessary since most individuals with LI can tolerate up to 12 grams of lactose daily in a single dose. Yogurts and cheeses matured for having low amounts of lactose are part of the strategy that allows consumption of dairy products by patients with LI. Currently, there is a diversity of products considered as “ milk substitutes ” and supplements aimed at individuals with LI. However, these strategies still require better-designed studies.RESUMO Os indiv íduo...
Source: Revista da Associacao Medica Brasileira - March 19, 2019 Category: General Medicine Source Type: research

Opioids in the immune system: from experimental studies to clinical practice
The objective of the study was to review the effects of opioids on the immune system. Methods: A search strategy was conducted in PubMed, Embase, and the Cochrane databases using the terms “ immunosuppression, ” “ immune system, ” “ surgical procedures, ” “ analgesics, ” “ opioids ” and “ perioperative care. ” Results: The immunosuppressive effect of opioids was identified over 30 years ago. They include signaling and acting directly through immune cells, including B and T lymphocytes, NK cells, monocytes, and macrophages, as well as activating the downstream pathways of the hypothalamic-pituita...
Source: Revista da Associacao Medica Brasileira - March 19, 2019 Category: General Medicine Source Type: research

Intraoperative vancomycin powder and post-operative infection after spinal surgery: a systematic review and meta-analysis
SUMMARY (Source: Revista da Associacao Medica Brasileira)
Source: Revista da Associacao Medica Brasileira - March 19, 2019 Category: General Medicine Source Type: research

Use of sodium-glucose cotransporter-2 inhibitors and urinary tract infections in type 2 diabetes patients: a systematic review
SUMMARY Sodium-glucose cotransporter-2 inhibitors (SGLT2i) are drugs that act by maintaining glycosuria. Recent studies have shown promising effects of these in the treatment of type 2 diabetes mellitus (DM2). However, there may be an increased risk of developing urinary tract infections (UTIs) in patients treated with these. Our study aims to analyze the association between the risk of UTI in patients treated with SGLT2i. A systematic review of the literature was carried out by randomized clinical trials, totalizing at the end of the selection 23 articles that were statistically evaluated. The incidence of UTI was general...
Source: Revista da Associacao Medica Brasileira - March 19, 2019 Category: General Medicine Source Type: research

The importance of the early diagnosis of aorta coarctation
CONCLUSION: Coarctation of the aorta is, therefore, a cardiac malformation of significant importance due to its incidence and its significant mortality risk. In this sense, the early diagnosis stands out as an essential piece for better prognosis of the patient.RESUMO INTRODU ÇÃO: A coarctação da aorta é uma cardiopatia congênita caracterizada por um estreitamento que ocorre na artéria aorta. Essa constrição pode ocorrer em qualquer local ao longo de toda a sua extensão, entretanto, é mais comum entre a origem da artéria subclávia esquerda e o ducto arterios o. Sua incidência corresponde a três casos a cada...
Source: Revista da Associacao Medica Brasileira - March 19, 2019 Category: General Medicine Source Type: research

Mapping scientific research on the negative aspects of the medical school learning environment
CONCLUSION: There is a definite increase in scientific articles on negative aspects of the medical school LE in high-quality journals, especially in the 21st century. However, more studies are needed to investigate negative LE aspects with greater attention to experimental, longitudinal, and cross-cultural study designs.RESUMO OBJETIVO: Buscou-se entender o panorama dos artigos publicados sobre os ambientes de aprendizagem (AA) das escolas m édicas em todo o mundo, com um foco explícito nos aspectos potencialmente negativos do AA como um esforço para identificar áreas especificamente necessitadas de remediação ou in...
Source: Revista da Associacao Medica Brasileira - March 19, 2019 Category: General Medicine Source Type: research

Nutritional and hematological factors associated with the progression of Alzheimer's disease: a cohort study
CONCLUSION: The hypothesis that patients are likely to be overweight or obese before the development of AD and that this may be associated with an increased risk of dementia is sugg ested.RESUMO OBJETIVO: Foram estudados os usu ários do programa de distribuição de medicamentos especializados da rede pública de saúde de Guarapuava, Paraná, Brasil. MÉTODOS: Uma coorte prospectiva, em que os idosos foram examinados em dois momentos, com um intervalo de três anos, com 30 pacientes na fase I e 16 na fase II. A metodolo gia foi composta por visitas domiciliares, avaliação antropométrica; avaliação nutricional e he...
Source: Revista da Associacao Medica Brasileira - March 19, 2019 Category: General Medicine Source Type: research

Treatment of aortic dissecting aneurysm involving visceral arteries with multi-layer bare stents
CONCLUSION: The treatment for aortic dissecting aneurysm involving the visceral arteries using multi-layer bare stents technique is safe and reliable with a higher patency rate of postoperative accumulated branch arteries.RESUMO Objetivo: Aneurismas dissecantes da aorta envolvendo art érias viscerais são de difícil tratamento clínico. O objetivo deste estudo foi explorar a eficácia e segurança clínica da técnica de stents multicamadas não farmacológicos para o tratamento de aneurismas dissecantes da aorta envolvendo artérias viscerais. Métodos: Foi feito um estudo re trospectivo usando os dados de 16 paciente...
Source: Revista da Associacao Medica Brasileira - March 19, 2019 Category: General Medicine Source Type: research

Unison of movements in football players with different nervous systems
In this study, we investigated the effect of typological features of nervous system properties on the ability to unite the movements of young football players. A total of 36 young football players aged 11-12 years participated in this experiment. Of them, 18 were engaged in an experimental differentiated method, which is based on using the same exercise and methods for developing the ability to unite movements but with different load components; for players with a strong nervous system (9 children), the load was intensive, but for players with a weak nervous system (9 children) - the load was volumetric. The other 18 athle...
Source: Revista da Associacao Medica Brasileira - March 19, 2019 Category: General Medicine Source Type: research

Ameliorative effect of certolizumab on experimentally induced acute necrotic pancreatitis in rats
CONCLUSION: The results support the idea that certolizumab might be beneficial for the severity of AP.RESUMO OBJETIVO: Os efeitos de Certolizumab, um anticorpo monoclonal pegilado para o fator de necrose tumoral α , na pancreatite aguda induzida experimentalmente (PA) foram examinados. M ÉTODO: Trinta e seis ratos Wistar Albino foram divididos aleatoriamente em quatro grupos. O Grupo I foi considerado o grupo controle e não recebeu medicação; o Grupo II foi o grupo Certolizumab e recebeu 100 ml/kg de soro fisiológico administrado no ducto biliopancreático e dose única de 10 m g Certolizumab administrada por via i...
Source: Revista da Associacao Medica Brasileira - March 19, 2019 Category: General Medicine Source Type: research

Axis screws: results and complications of a large case series
CONCLUSION: Axis screw instrumentation proved to be a safe and efficient method for cervical stabilization. Laminar and pars screws were the most commonly usedRESUMO OBJETIVO: Apresentar os resultados cir úrgicos de pacientes submetidos à instrumentação com parafusos do áxis, discutindo nuances cirúrgicas e complicações das técnicas utilizadas. MÉTODOS: Série retrospectiva de pacientes submetidos à instrumentação do áxis utilizando parafusos. RESULTADOS: Sessenta e cinco pacientes fo ram incluídos neste estudo. A causa mais comum de instabilidade foi trauma raquimedular envolvendo o áxis (36 pacientes ...
Source: Revista da Associacao Medica Brasileira - March 19, 2019 Category: General Medicine Source Type: research

Differentiation between stercoral perforation and colorectal cancer perforation
CONCLUSION: Fecaloma in the proximal colon and layered enhancing wall thickening adjacent to perforation site are likely due to stercoral perforation. Eccentric bowel wall thickening at the distal portion of the perforation site with many enlarged pericolonic lymph nodes is most likely due to colorectal cancer perforation.RESUMO OBJETIVO: Determinar os sinais de CT associados à perfuração estercoral e perfuração do câncer colorretal. MÉTODOS: De maio de 2003 a fevereiro de 2015, todos os pacientes cirurgicamente e patologicamente confirmados com perfuração estercoral (n = 8, idade média de 68,3 anos) ou perfura...
Source: Revista da Associacao Medica Brasileira - March 19, 2019 Category: General Medicine Source Type: research