An immunohistochemistry and histopathological study of ankaferd blood stopper in a rat model of cervical inflammation
CONCLUSION: Our data suggest that ABS is a highly effective alternative to induce normal cervical epithelium and can be used safely in the treatment of cervical inflammation with or without cervical erosion.RESUMO OBJETIVO: Ankaferd Blood Stopper (ABS) é um extrato de plantas medicinais utilizado topicamente como um agente hemostático, anti-inflamatório e antioxidante. O seu efeito citoproteico depende principalmente das suas propriedades pleiotrópicas por meio da modulação de mediadores inflamatórios tais como IL-1 β , IL-6 e TNF-a. O objetivo deste estudo é testar o possível efeito terapêutico do ABS no trata...
Source: Revista da Associacao Medica Brasileira - March 19, 2019 Category: General Medicine Source Type: research

Effect of FOLFOX6 chemotherapy on serum VEGF expression in advanced colorectal cancer patients
CONCLUSION: FOLFOX6 chemotherapy can decrease serum VEGF expression in patients with advanced colorectal cancer and enhance the curative effect with high safety, which is good for the improvement of patients' survival.RESUMO OBJETIVO: Explorar o efeito da quimioterapia Folfox6 na express ão do fator de crescimento endotelial vascular sérico (VEGF) em pacientes com câncer colorretal avançado. MÉTODOS: Uma análise retrospectiva de 81 pacientes com câncer colorretal avançado que visitaram nosso hospital de março de 2014 a fevereiro de 2016 foi realizada. Todos os pacientes fo ram tratados com quimioterapia Folfox6....
Source: Revista da Associacao Medica Brasileira - March 19, 2019 Category: General Medicine Source Type: research

Daily genital cares of female gynecologists: a descriptive study
Conclusion: Genital hygiene habits of female gynecologists can be improved, despite the high grade of scientific knowledge they hold.RESUMO INTRODU ÇÃO: A higiene genital pode desempenhar um papel importante na prevenção de desconfortos vulvovaginais e infecções. Evidências científicas sobre as melhores práticas em higiene genital são escassas, e o ginecologista, sem dúvida, é a melhor pessoa para discutir e orientar o assunto. OBJ ETIVO: Avaliar a higiene genital feminina usual de médicas ginecologistas. MÉTODOS: Estudo analítico descritivo que identificou higiene genital e práticas sexuais de 220 ginec...
Source: Revista da Associacao Medica Brasileira - March 19, 2019 Category: General Medicine Source Type: research

The primacy of ultrasound in the assessment of muscle architecture: precision, accuracy, reliability of ultrasonography. Physiatrist, radiologist, general internist, and family practitioner's experiences
CONCLUSION: Simple, reproducible, non-invasive ultrasound measurements of muscle structure easily demonstrated differences in muscle morphology. With a protocol and with objective and repeatable measurements, sonographers from different backgrounds could obtain an objective measurement of ultrasound images with little differences and low variability in results, thanks to the upgrading of diagnostic ultrasound imaging and their clinical skills.RESUMO OBJETIVO: N ós utilizamos ultrassonografia de alta resolução em tempo real para investigar os parâmetros da arquitetura muscular do vasto lateral em voluntários saudávei...
Source: Revista da Associacao Medica Brasileira - March 19, 2019 Category: General Medicine Source Type: research

Analgesic effects of a capacitive-resistive monopolar radiofrequency in patients with myofascial chronic neck pain: a pilot randomized controlled trial
CONCLUSIONS: Even though there were no differences between both groups, the monopolar capacitive, resistive RF could have a potential effect on pain intensity.RESUMO ANTECEDENTES: At é a data, há uma falta de estudos prévios para tratar a dor no pescoço por radiofrequência (RF) monopolar capacitiva resistiva. O objetivo deste estudo foi investigar o efeito imediato da radiofrequência monopolar capacitiva resistiva (RF = 448 kHz) versus placebo em (1) redução da intensida de da dor no pescoço em pontos de gatilho miofascial (MTrP), (2) diminuição da incapacidade do pescoço e (3) melhorando a amplitude de movime...
Source: Revista da Associacao Medica Brasileira - March 19, 2019 Category: General Medicine Source Type: research

Association between sex differences on foot health related to the quality of life in a sample of sedentary people
SUMMARY Sedentary (sitting) time may produce many anatomical and physiological consequences which are supposedly associated with a decreased quality of life (QoL) related to foot health. Accordingly, this study aimed to analyze the QoL impact on the overall health and the foot health among male and female sedentary people. A total of 312 participants with an age mean of 39.81 ± 15.40 years completed all phases of the study. In addition, self-reported data were registered. The participants' sedentary lifestyle was determined using the European Prospective Investigation into Cancer and Nutrition (EPIC) physical activity que...
Source: Revista da Associacao Medica Brasileira - March 19, 2019 Category: General Medicine Source Type: research

Determination of Mirabegron in rat plasma by UPLC–MS/MS after oral and intravenous administration
SUMMARY Mirabegron is a kind of β 3 adrenergic receptor agonist which is an effective drug for the treatment of overactive bladder. In this research, a UPLC – MS/MS method is developed and validated for the study of mirabegron pharmacokinetic in rats. A protein precipitation method is applied for sample preparation with acetonitrile. m/z 397.3 → 379.6, m/z 326.4 → 121.0 for mirabegron, tolterodine (IS), respectively in the positive ion mode was performed for quantitation. The method is reliable and reproducible in our study (intra-day precision ≤ 11.06%, inter-day precision ≤ 11.43%) with concentration curves li...
Source: Revista da Associacao Medica Brasileira - March 19, 2019 Category: General Medicine Source Type: research

Primary infratentorial diffuse large b-cell lymphoma: a challenging diagnosis in an immunocompetent patient
We describe the case of a female patient, 52 years old, with dizziness and left motor incoordination for 2 weeks. Brain MRI magnetic resonance imaging) revealed a hyperintense lesion on T2-weighted images, without restricted diffusion, in the left middle cerebellar peduncle. Spectroscopy demonstrated peak of lipids and perfusion did not show any elevation in relative cerebral blood volume (rCBV). The patient underwent an open biopsy and resection, and the diagnosis of diffuse large B-cell lymphoma (DLBCL) was established. The patient received intravenous dexamethasone with symptoms remission, followed by four cycles of met...
Source: Revista da Associacao Medica Brasileira - March 19, 2019 Category: General Medicine Source Type: research

Non-puerperal uterine inversion associated with myomatosis
SUMMARY Uterine inversion is an uncommon complication of the puerperium and it is an even rarer complication of the non-puerperal period. In this way, uterine inversions are classified into two groups, being of puerperal origin due to obstetric problems and non-puerperal origin due to gynecological problems. In general, a non-puerperal uterine inversion occurs as a possible complication of a sub mucosal leiomyoma, after an expansive process, a dilation of the cervix occurs and thus its protuberance over the vaginal canal.RESUMO A invers ão uterina é uma complicação incomum do puerpério e é uma complicação ainda mai...
Source: Revista da Associacao Medica Brasileira - March 19, 2019 Category: General Medicine Source Type: research

Non-ketotic hyperosmolar hyperglycemic chorea
We report this case of a rare complication of chronic pancreatitis to show that color-Doppler ultrasound is a non-invasive and effective diagnostic tool for pseudoaneurysm, which enables early detection and prompt treatment without the need for invasive diagnostic modalities. (Source: Revista da Associacao Medica Brasileira)
Source: Revista da Associacao Medica Brasileira - March 19, 2019 Category: General Medicine Source Type: research

A pancreatic hemorrhagic pseudocyst with pseudoaneurysm and the role of doppler ultrasonography: a case report
We report this case of a rare complication of chronic pancreatitis to show that color-Doppler ultrasound is a non-invasive and effective diagnostic tool for pseudoaneurysm, which enables early detection and prompt treatment without the need for invasive diagnostic modalities. (Source: Revista da Associacao Medica Brasileira)
Source: Revista da Associacao Medica Brasileira - March 19, 2019 Category: General Medicine Source Type: research

APnet, an innovative multidisciplinary medical information platform for acute pancreatitis
SUMMARY The APnet information platform aims at assisting patients suffering from acute pancreatitis, health professionals and patients' relatives in the acute pancreatitis care pathway by providing an integrated information system. The system consists of a mobile platform and a Clinical Information System. The system is currently on the formal operation phase focusing on addressing the needs of citizens of China.RESUMO A plataforma de informa ções APnet tem como objetivo auxiliar pacientes que sofrem de pancreatite aguda, profissionais da saúde e familiares de pacientes no percurso de cuidados para a pancreatite aguda, ...
Source: Revista da Associacao Medica Brasileira - March 19, 2019 Category: General Medicine Source Type: research

The overexpression of lncRNA H19 as a diagnostic marker for coronary artery disease
Conclusion: H19 overexpression participates in the pathogenesis of CAD by increasing the expression level of TGF- β 1, and H19 expression level may serve as a diagnostic marker for CAD.RESUMO OBJETIVO Nosso estudo teve como objetivo investigar o valor diagn óstico do lncRNA H19 para doença arterial coronariana (DAC) e explorar os possíveis mecanismos. Métodos Um total de 30 pacientes com DAC e 30 pessoas saudáveis, bem como pacientes com diferentes doenças cardiovasculares foram incluídos neste estudo. O sangue foi extraído de cada participant e para preparar amostras de soro e a expressão de lncRNA H19 foi det...
Source: Revista da Associacao Medica Brasileira - March 19, 2019 Category: General Medicine Source Type: research

Observations on multi-generational interactions in academic surgical practice and education
SUMMARY Although there is a natural passage of responsibilities and duties from one generation to the next in any organization, academic or otherwise, managing intergenerational differences is challenging. In academic surgery, in which there are duties to patients, institutional administrators, faculty colleagues, resident trainees, and medical students are faced with multi-generations of individuals who have their own perspectives of what is “ required ” of them and what is “ fulfilling ” to them. The purpose of this essay is to relate our observations of the challenges and opportunities to manage these relation...
Source: Revista da Associacao Medica Brasileira - March 19, 2019 Category: General Medicine Source Type: research

Laparoscopic renal biopsy
The Guidelines Project, an initiative of the Brazilian Medical Association, aims to combine information from the medical field in order to standardize producers to assist the reasoning and decision-making of doctors. The information provided through this project must be assessed and criticized by the physician responsible for the conduct that will be adopted, depending on the conditions and the clinical status of each patient. (Source: Revista da Associacao Medica Brasileira)
Source: Revista da Associacao Medica Brasileira - March 19, 2019 Category: General Medicine Source Type: research