Impact of implementing a protocol of respiratory care measures and optimization of mechanical ventilation in potential lung donors
RESUMEN Objetivo: Describir los resultados de la implementaci ón de un protocolo de cuidados respiratorios y de ventilación mecánica en el potencial donante de pulmón, que cumplen las condiciones para ser procurados. El objetivo secundario es comparar los resultados con datos históricos. Métodos: Estudio retrospectivo y observacional. Incluye potenciale s donantes aptos para procuración de órganos con muerte encefálica internados en las áreas críticas de la Ciudad Autónoma de Buenos Aires, desde abril de 2017 hasta marzo de 2018. Variables principales: número de potencial donante de pulmón que alcanzan el o...
Source: Revista Brasileira de Terapia Intensiva - January 13, 2021 Category: Intensive Care Source Type: research

Hemodynamically stable oliguric patients usually do not respond to fluid challenge
Conclusion: After achieving hemodynamic stability, oliguric patients did not increase urine output after a fluid challenge. Systemic hemodynamic, perfusion or renal parameters were weak predictors of urine responsiveness. Our results suggest that volu me replacement to correct oliguria in patients without obvious hypovolemia should be done with caution. (Source: Revista Brasileira de Terapia Intensiva)
Source: Revista Brasileira de Terapia Intensiva - January 13, 2021 Category: Intensive Care Source Type: research

Impact of the use of nephrotoxic drugs in critically ill pediatric patients
Conclusion: It is necessary for intensivist physicians to have knowledge of the main nephrotoxic drugs to predict, reduce or avoid damage to their patients. (Source: Revista Brasileira de Terapia Intensiva)
Source: Revista Brasileira de Terapia Intensiva - January 13, 2021 Category: Intensive Care Source Type: research

Clinical outcome of children with fluid-refractory septic shock treated with dopamine or epinephrine. A retrospective study at a pediatric emergency department in Argentina
Conclusiones: En nuestro centro, no observamos diferencias en uso de ventilación mecánica invasiva y tiempo de inotrópicos, estancia hospitalaria y cuidados intensivos y mortalidad entre niños ingresados al servicio de urgencias pediátrico con diagnóstico de shock séptico refr actario a volumen tratados inicialmente con dopamina o adrenalina.Abstract Objective: To analyze the clinical outcome of children with fluid-refractory septic shock initially treated with dopamine or epinephrine. Methods: A retrospective cohort study was conducted at a pediatric emergency department of a tertiary hospital. Population: childr...
Source: Revista Brasileira de Terapia Intensiva - January 13, 2021 Category: Intensive Care Source Type: research

Outcomes after intra-aortic balloon pump insertion in cardiac surgery patients
Conclusion: Preoperative insertion of an intra-aortic balloon pump was not associated with a lower 30-day mortality or reduced length of postoperative hospital stay compared to intraoperative insertion. (Source: Revista Brasileira de Terapia Intensiva)
Source: Revista Brasileira de Terapia Intensiva - January 13, 2021 Category: Intensive Care Source Type: research

Viability and validity of the bispectral index to measure sleep in patients in the intensive care unit
Conclusion: The bispectral index is an instrument with limited viability to monitor the sleep of lucid patients and patients wi th low to moderate disease severity in the intensive care unit. Patients with higher total sleep volume, total sleep time, and continuous sleep volume had better overall sleep perception. (Source: Revista Brasileira de Terapia Intensiva)
Source: Revista Brasileira de Terapia Intensiva - January 13, 2021 Category: Intensive Care Source Type: research

Mechanical ventilation withdrawal as a palliative procedure in a Brazilian intensive care unit
Conclusion: In this Brazilian report, mechanical ventilation withdrawal represented 11% of all patients with treatment limitations and was not associated with increased hospital mortality after propensity score matching on relevant covariates. (Source: Revista Brasileira de Terapia Intensiva)
Source: Revista Brasileira de Terapia Intensiva - January 13, 2021 Category: Intensive Care Source Type: research

Comparison of SAPS 3 performance in patients with and without solid tumor admitted to an intensive care unit in Brazil: a retrospective cohort study
Conclusion: SAPS 3 performed differently between oncological and nononcological patients in our single-center cohort, and variation over time (mainly calibration) was observed. This finding should be taken into account when evaluating severity-of-illness score performance. (Source: Revista Brasileira de Terapia Intensiva)
Source: Revista Brasileira de Terapia Intensiva - January 13, 2021 Category: Intensive Care Source Type: research

Incidence of low-triiodothyronine syndrome in patients with septic shock
Conclusion: Patients with septic shock have a high incidence of alteration of the thyroid axis, and this dysfunction is associated with higher mortality. (Source: Revista Brasileira de Terapia Intensiva)
Source: Revista Brasileira de Terapia Intensiva - January 13, 2021 Category: Intensive Care Source Type: research

Value of the urea/creatinine index in isolated urine to estimate severe protein hypercatabolism in ventilated patients
Conclusion: The urea/creatinine index measured on the fourth day has a certain ability to estimate severe protein hypercatabolism (as defined by estimated total urinary nitrogen) but does not replace total urinary nitrogen in critically ventilated patients without kidney failure. Due to its reasonable sensitivity, it could be used as a screen to identify which patients to take a 24-hour urine sample from. (Source: Revista Brasileira de Terapia Intensiva)
Source: Revista Brasileira de Terapia Intensiva - January 13, 2021 Category: Intensive Care Source Type: research

Statistical analysis plan for the Balanced Solution versus Saline in Intensive Care Study (BaSICS)
Conclusion: This manuscript provides details on the first version of the statistical analysis plan for the BaSICS trial and will guide the study ’ s analysis when follow-up is finished. (Source: Revista Brasileira de Terapia Intensiva)
Source: Revista Brasileira de Terapia Intensiva - January 13, 2021 Category: Intensive Care Source Type: research

Clinical characteristics and predictors of mechanical ventilation in patients with COVID-19 hospitalized in Southern Brazil
Conclusion: Our findings describe the first wave of Brazilian patients hospitalized for COVID-19. Age was the strongest predictor of respiratory insufficiency and the need for mechanical ventilation in our population. (Source: Revista Brasileira de Terapia Intensiva)
Source: Revista Brasileira de Terapia Intensiva - January 13, 2021 Category: Intensive Care Source Type: research

Early mobilization in the time of COVID-19
(Source: Revista Brasileira de Terapia Intensiva)
Source: Revista Brasileira de Terapia Intensiva - January 13, 2021 Category: Intensive Care Source Type: research

To: Adequacy of enteral nutritional support in intensive care units does not affect short- and long-term prognosis of mechanically ventilated patients: a pilot study
We report the case of a 23-year-old male admitted to the Intensive Care Unit with sudden onset of fever, generalized muscle pain associated with liver failure, and disseminated intravascular coagulation. The results of conventional laboratory tests showed thrombocytopenia, whereas thromboelastometry suggested coagulopathy with slight hypofibrinogenemia, clotting factor consumption, and, consequently, an increased risk of bleeding. Unlike conventional laboratory tests, thromboelastometry identified the specific coagulation disorder and thereby guided hemostatic therapy. Both fibrinogen concentrates and vitamin K were admini...
Source: Revista Brasileira de Terapia Intensiva - October 12, 2020 Category: Intensive Care Source Type: research

Memory box: possibilities to support grief in the intensive care unit during the COVID-19 pandemic
We report the case of a 23-year-old male admitted to the Intensive Care Unit with sudden onset of fever, generalized muscle pain associated with liver failure, and disseminated intravascular coagulation. The results of conventional laboratory tests showed thrombocytopenia, whereas thromboelastometry suggested coagulopathy with slight hypofibrinogenemia, clotting factor consumption, and, consequently, an increased risk of bleeding. Unlike conventional laboratory tests, thromboelastometry identified the specific coagulation disorder and thereby guided hemostatic therapy. Both fibrinogen concentrates and vitamin K were admini...
Source: Revista Brasileira de Terapia Intensiva - October 12, 2020 Category: Intensive Care Source Type: research