Leptospirosis in an urban setting: cases diagnosed at a private medical center of Western Colombia, 2008-2012(†).
CONCLUSION: Leptospirosis is an emerging infectious disease that has changed from an occupational disease of veterinarians, farmers, butchers, and other animal handlers to a cause of epidemics in poor and decayed urban communities in developing countries, including those in Latin America such as Colombia. PMID: 25873099 [PubMed - in process] (Source: Recent Patents on Anti-Infective Drug Discovery)
Source: Recent Patents on Anti-Infective Drug Discovery - June 4, 2015 Category: Infectious Diseases Tags: Recent Pat Antiinfect Drug Discov Source Type: research

MERS-CoV An Emerging Viral Zoonotic Disease: Three Years After and Counting.
Authors: Memish ZA PMID: 25876750 [PubMed - as supplied by publisher] (Source: Recent Patents on Anti-Infective Drug Discovery)
Source: Recent Patents on Anti-Infective Drug Discovery - June 4, 2015 Category: Infectious Diseases Tags: Recent Pat Antiinfect Drug Discov Source Type: research

Cancer targeted magic bullets for effective treatment of cancer.
Authors: Aneja P, Rahman M, Beg S, Aneja S, Dhingra V, Chugh R Abstract Cancer is a multifaceted disorder with serious threat across the globe. The vision for accomplishing an effective treatment strategy for cancer has always been a major concern worldwide. Although conventional drug therapy, esp. the chemotherapeutics provide benefits upto certain extent for treatment and management of cancers, yet it possesses umpteen challenges in terms of the associated side effects and adverse effects, lack of targeting ability, multi-drug resistance, poor patient acceptance and compliance, etc. at the desired site. ...
Source: Recent Patents on Anti-Infective Drug Discovery - June 4, 2015 Category: Infectious Diseases Tags: Recent Pat Antiinfect Drug Discov Source Type: research

Opinion paper: pharmacogenomics testing for type B adverse drug reactions to anti- infective drugs: the example of hypersensitivity to abacavir.
Authors: Agundez JA, Esguevillas G, Amo G, Garcia-Martin E PMID: 25891395 [PubMed - in process] (Source: Recent Patents on Anti-Infective Drug Discovery)
Source: Recent Patents on Anti-Infective Drug Discovery - June 4, 2015 Category: Infectious Diseases Tags: Recent Pat Antiinfect Drug Discov Source Type: research

Anti-Viral Agents in Neurodegenerative Disorders: New Paradigm for Targeting Alzheimer's Disease.
Authors: Faldu KG, Shah JS, Patel SS Abstract Alzheimer's disease (AD) is a neurodegenerative disease affecting geriatric populations for which several causes have been proposed. These include a relationship with known pathogens although the exact nature of such a relationship remains uncertain. Herpes simplex virus-1 has been proposed as potential cause of AD because of its ability to form ß amyloid(Aß) and neurofibrillary tangles due to tau hyperphosphorylation and action of beta & gamma secretase on amyloid precursor protein(APP) together with genetic association with apolipoprotein-E4(ApoE-Ɛ4), ...
Source: Recent Patents on Anti-Infective Drug Discovery - June 4, 2015 Category: Infectious Diseases Tags: Recent Pat Antiinfect Drug Discov Source Type: research

Editorial: Challenges for Fish Foodborne Parasitic Zoonotic Diseases (Part II).
Authors: Rodríguez-Morales AJ PMID: 26003167 [PubMed - in process] (Source: Recent Patents on Anti-Infective Drug Discovery)
Source: Recent Patents on Anti-Infective Drug Discovery - June 4, 2015 Category: Infectious Diseases Tags: Recent Pat Antiinfect Drug Discov Source Type: research

Nanomachines and "nanosolutions": they are changing the perspective of medical treatments.
NANOMACHINES AND "NANOSOLUTIONS": THEY ARE CHANGING THE PERSPECTIVE OF MEDICAL TREATMENTS. Recent Pat Antiinfect Drug Discov. 2015 May 29; Authors: da Silva LE Abstract In Medicinal Chemistry "size plays a role". With this expression known in many differents countries we stand today on the edge of a new frontier of nanotechnology: nominally known as nanoterapy. In this context nanomaterials applied in nanotherapeutic should have a plataform with capacity for carrying diverse molecular cargo such as small molecules, drugs with physiological properties, sIRNAs, peptides as well as i...
Source: Recent Patents on Anti-Infective Drug Discovery - June 4, 2015 Category: Infectious Diseases Tags: Recent Pat Antiinfect Drug Discov Source Type: research