Invited Editorial: Malaria by Plasmodium knowlesi, A Zoonosis Transmitted by Vectors.
Authors: Machado-Alba JE PMID: 25851255 [PubMed - in process] (Source: Recent Patents on Anti-Infective Drug Discovery)
Source: Recent Patents on Anti-Infective Drug Discovery - June 4, 2015 Category: Infectious Diseases Tags: Recent Pat Antiinfect Drug Discov Source Type: research

Invited editorial: zoonotic lymphatic filariasis in the americas: trends in epidemiology, diagnosis and treatment, with special emphasis on brugian filariasis.
Authors: Paniz Mondolfi AE, Sordillo EM PMID: 25851428 [PubMed - in process] (Source: Recent Patents on Anti-Infective Drug Discovery)
Source: Recent Patents on Anti-Infective Drug Discovery - June 4, 2015 Category: Infectious Diseases Tags: Recent Pat Antiinfect Drug Discov Source Type: research

Human anthrax as a re-emerging disease.
Authors: Doganay M, Demiraslan H Abstract Anthrax is primarily a disease of herbivores and the etiological agent is B. anthracis which is a gram-positive, aerobic, spore-forming, and rod shaped bacterium. Bacillus anthracis spores are highly resistant to heat, pressure, ultraviolet and ionizing radiation, chemical agents and disinfectants. For these reasons, B. anthracis spores are an attractive choice as biological agents for the use of bioweapon and/or bioterrorism. Soil is the main reservoir for the infectious agent. The disease most commonly affects wild and domestic mammals. Human are secondarily infe...
Source: Recent Patents on Anti-Infective Drug Discovery - June 4, 2015 Category: Infectious Diseases Tags: Recent Pat Antiinfect Drug Discov Source Type: research

Brucellosis and its particularities in children travelers.
Authors: Bosilkovski M, Rodriguez-Morales AJ Abstract Brucellosis is still endemic in many countries in the world, however, having a significantly higher incidence in developing countries. As consequence of travel, risk for children from non-endemic areas would be considerable when visiting developing countries. Then, the purpose of this review is to provide, after a bibliographical search, an update on the main aspects of this disease in the traveler children. For the general practitioner, but particularly for travel medicine practitioner and pediatricians, these clinicoepidemiological considerations shou...
Source: Recent Patents on Anti-Infective Drug Discovery - June 4, 2015 Category: Infectious Diseases Tags: Recent Pat Antiinfect Drug Discov Source Type: research

Bibliometric assessment of the latin-american contributions in dengue.
CONCLUSIONS: Brazil is the best producer in the region. In Puerto Rico and Brazil, there observed the epidemiologic burden of the disease. Scientific production in bibliographical data bases, particularly regional, is low, as compared to the high impact of the disease of in urban zones of the region. PMID: 25858260 [PubMed - in process] (Source: Recent Patents on Anti-Infective Drug Discovery)
Source: Recent Patents on Anti-Infective Drug Discovery - June 4, 2015 Category: Infectious Diseases Tags: Recent Pat Antiinfect Drug Discov Source Type: research

Dengue Patients Treated with Doxycycline Showed Lower Mortality Associated to a Reduction in IL-6 and TNF Levels.
CONCLUSION: The above findings suggest that doxycycline can provide a clinical benefit to dengue patients at high risk of complications. This effect could be mediated by decreasing pro-inflammatory cytokine levels. PMID: 25858261 [PubMed - in process] (Source: Recent Patents on Anti-Infective Drug Discovery)
Source: Recent Patents on Anti-Infective Drug Discovery - June 4, 2015 Category: Infectious Diseases Tags: Recent Pat Antiinfect Drug Discov Source Type: research

Bibliometric assessment of the contributions of literature on chagas disease in latin america and the Caribbean.
This study used SCI (1980-2013), MEDLINE/GOPUBMED (1802-2013), Scopus (1959-2013), SCIELO (2004-2013), and LILACS (1980-2013). Different study types have been characterized by years, origin city/country, journals and most productive authors, by country, cites and H-index. 2988 articles were retrieved from SCI (30.85% of total). Brazil was found to be the highest producer (31.22%), followed by Argentina (18.14%) and México (9.57%); the region received 47241 citations, 28.60% for Brazil (H-index=52), 18.26% of Argentina (Hindex= 43), 11.40% Bolivia (H-index=37). 4484 were retrieved from Scopus (30.20% of the total), 38.58% ...
Source: Recent Patents on Anti-Infective Drug Discovery - June 4, 2015 Category: Infectious Diseases Tags: Recent Pat Antiinfect Drug Discov Source Type: research

Scientific research in malaria: bibliometric assessment of the latin-american contributions.
CONCLUSIONS: Brazil has the highest output of the region, as Venezuela the scientific production in Malaria was related with the burden of disease. This was not the case for Colombia. Scientific production at bibliographical databases, particularly regionals, is low, compared to the high incidence of this disease that requires more research and control. PMID: 25858269 [PubMed - in process] (Source: Recent Patents on Anti-Infective Drug Discovery)
Source: Recent Patents on Anti-Infective Drug Discovery - June 4, 2015 Category: Infectious Diseases Tags: Recent Pat Antiinfect Drug Discov Source Type: research

Study of the scientific production on leishmaniasis in latin america.
CONCLUSIONS: Scientific production of Brazil predominates in the region, with one single institution generating more articles than Colombia and Venezuela together. Scientific production in bibliographical data bases, particularly regional, is still relatively low, and the disease neglected when compared to other tropical conditions such as dengue and malaria. PMID: 25858270 [PubMed - in process] (Source: Recent Patents on Anti-Infective Drug Discovery)
Source: Recent Patents on Anti-Infective Drug Discovery - June 4, 2015 Category: Infectious Diseases Tags: Recent Pat Antiinfect Drug Discov Source Type: research

Anti-toxoplasma activity of natural products: a review.
Authors: Sepulveda-Arias JC, Veloza LA, Mantilla-Muriel LE Abstract Toxoplasma gondii is an intracellular parasite widely distributed in nature. Infection is asymptomatic in immunocompetent individuals; however, various clinical manifestations may occur in immunocompromised individuals. Although there are medications for the treatment of toxoplasmosis, such as pyrimethamine and sulfonamide, they cannot always be used due to adverse reactions or to therapeutic failures related to intolerance or malabsorption of drugs and to parasite drug resistance. In recent years, the search for new antimicrobial agents d...
Source: Recent Patents on Anti-Infective Drug Discovery - June 4, 2015 Category: Infectious Diseases Tags: Recent Pat Antiinfect Drug Discov Source Type: research

Ocular toxocariasis: new diagnostic and therapeutic perspectives.
CONCLUSION: Toxocariasis is still a problem of public health, particularly in developing countries with an increasing epidemiological burden in terms of morbidity and mortality and most of the authors agree on the utmost relevance of its prevention. Clinical experience and suspicion of ophthalmologists make an important role in its diagnosis, but always with supportive diagnostic methods. Additional studies should explore new therapeutic options for toxocariasis. PMID: 25858303 [PubMed - in process] (Source: Recent Patents on Anti-Infective Drug Discovery)
Source: Recent Patents on Anti-Infective Drug Discovery - June 4, 2015 Category: Infectious Diseases Tags: Recent Pat Antiinfect Drug Discov Source Type: research

The present situation of human taeniases and cysticercosis in Asia.
Authors: Ito A, Wandra T, Li T, Dekumyoy P, Nkouawa A, Okamoto M, Budke CM Abstract Three human Taenia species, Taenia solium, Taenia saginata, and Taenia asiatica, are endemic in rural regions of Asia, with these species sympatrically distributed in parts of Thailand and China. The pork tapeworm, T. solium, is the most pathogenic to humans, causing cysticercosis and neurocysticercosis (NCC). Due to its public health impact, T. solium taeniasis/cysticercosis is one of 17 neglected tropical diseases (NTDs) prioritized by the World Health Organization. In this review, the current status of taeniasis and NCC ...
Source: Recent Patents on Anti-Infective Drug Discovery - June 4, 2015 Category: Infectious Diseases Tags: Recent Pat Antiinfect Drug Discov Source Type: research

Rabies in South Asia: fighting for elimination.
Authors: Chowdhury FR, Basher A, Amin MR, Hassan N, Patwary MI Abstract South Asia is regarded as the hot spot for the tourist and travelers. Unfortunately, three big countries (India, Pakistan and Bangladesh) of this region belong to top five rabies endemic countries of the world. Around 55,000 people die of rabies every year globally and 45% of them belong to South and South East Asia. Countries are now working on the elimination of rabies by the year 2020. Elimination of animal rabies is the pivotal of controlling human rabies. Dog (primary source) registration, population control and mass vaccination a...
Source: Recent Patents on Anti-Infective Drug Discovery - June 4, 2015 Category: Infectious Diseases Tags: Recent Pat Antiinfect Drug Discov Source Type: research

Geographical and occupational aspects of leptospirosis in the coffee-triangle region of Colombia, 2007-2011.
CONCLUSION: one of the 53 municipalities contributed with almost a quarter of the cases. Agriculture was significantly associated with the incidence. Use of GIS-based epidemiological maps allow to focus actions in prevention and control for risk zones for leptospirosis which still represents a significant issue in the region and Colombia, particularly in agriculture workers. PMID: 25858306 [PubMed - in process] (Source: Recent Patents on Anti-Infective Drug Discovery)
Source: Recent Patents on Anti-Infective Drug Discovery - June 4, 2015 Category: Infectious Diseases Tags: Recent Pat Antiinfect Drug Discov Source Type: research

Letter to editor: from imported to an endemic disease: impact of chikungunya virus disease in the hospital epidemiology, tolima, Colombia, 2014-2015.
Authors: Jimenez-Canizales CE, Medina-Gaitan DA, Mondragon-Cardona ÁE, Rodriguez-Morales AJ PMID: 25873098 [PubMed - in process] (Source: Recent Patents on Anti-Infective Drug Discovery)
Source: Recent Patents on Anti-Infective Drug Discovery - June 4, 2015 Category: Infectious Diseases Tags: Recent Pat Antiinfect Drug Discov Source Type: research