Modulation of the chemokine/chemokine receptor axis as a novel approach for glioma therapy
Publication date: Available online 11 December 2020Source: Pharmacology & TherapeuticsAuthor(s): Gregory P. Takacs, Joseph A. Flores-Toro, Jeffrey K. Harrison (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - December 12, 2020 Category: Drugs & Pharmacology Source Type: research

A deep dive into UV-based phototherapy: Mechanisms of action and emerging molecular targets in inflammation and cancer
Publication date: Available online 11 December 2020Source: Pharmacology & TherapeuticsAuthor(s): Pablo A. Vieyra-Garcia, Peter Wolf (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - December 12, 2020 Category: Drugs & Pharmacology Source Type: research

Functional and Biochemical Consequences of Disease Variants in Neurotransmitter Transporters: A Special Emphasis on Folding and Trafficking Deficits
Publication date: Available online 10 December 2020Source: Pharmacology & TherapeuticsAuthor(s): Shreyas Bhat, Ali El-Kasaby, Michael Freissmuth, Sonja Sucic (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - December 12, 2020 Category: Drugs & Pharmacology Source Type: research

The evolving obesity challenge: Targeting the vagus nerve and the inflammatory reflex in the response
Publication date: Available online 10 December 2020Source: Pharmacology & TherapeuticsAuthor(s): Valentin A. Pavlov (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - December 12, 2020 Category: Drugs & Pharmacology Source Type: research

Medicinal chemistry, pharmacology, and therapeutic potential of α-conotoxins antagonizing the α9α10 nicotinic acetylcholine receptor
Publication date: Available online 10 December 2020Source: Pharmacology & TherapeuticsAuthor(s): Xiao Li, Han-Shen Tae, Yanyan Chu, Tao Jiang, David J. Adams, Rilei Yu (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - December 11, 2020 Category: Drugs & Pharmacology Source Type: research

The multifaceted functions of RNA helicases in the adaptive cellular response to hypoxia: From mechanisms to therapeutics
Publication date: Available online 8 December 2020Source: Pharmacology & TherapeuticsAuthor(s): Yijie Wang, Guangqiang Li, Mingxia Deng, Xiong Liu, Weixiao Huang, Yao Zhang, Min Liu, Yan Chen (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - December 9, 2020 Category: Drugs & Pharmacology Source Type: research

PET imaging of immune checkpoint proteins in oncology
Publication date: Available online 8 December 2020Source: Pharmacology & TherapeuticsAuthor(s): Alizée Bouleau, Vincent Lebon, Charles Truillet (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - December 9, 2020 Category: Drugs & Pharmacology Source Type: research

Transglutaminase 2 as a novel target in chronic kidney disease – Methods, mechanisms and pharmacological inhibition
Publication date: Available online 9 December 2020Source: Pharmacology & TherapeuticsAuthor(s): Judit Prat-Duran, Estéfano Pinilla, Rikke Nørregaard, Ulf Simonsen, Niels Henrik Buus (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - December 9, 2020 Category: Drugs & Pharmacology Source Type: research

Molecular mechanisms and cardiovascular implications of cancer therapy-induced senescence
Publication date: Available online 1 December 2020Source: Pharmacology & TherapeuticsAuthor(s): Ibrahim Y. Abdelgawad, Karim T. Sadak, Diana W. Lone, Mohamed S. Dabour, Laura J. Niedernhofer, Beshay N. Zordoky (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - December 2, 2020 Category: Drugs & Pharmacology Source Type: research

A comprehensive guide to the pharmacologic regulation of angiotensin converting enzyme 2 (ACE2), the SARS-CoV-2 entry receptor
Publication date: Available online 1 December 2020Source: Pharmacology & TherapeuticsAuthor(s): Murat Oz, Dietrich Ernst Lorke, Nadine Kabbani (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - December 2, 2020 Category: Drugs & Pharmacology Source Type: research

The emerging role of leukemia inhibitory factor in cancer and therapy
Publication date: Available online 28 November 2020Source: Pharmacology & TherapeuticsAuthor(s): Cen Zhang, Juan Liu, Jianming Wang, Wenwei Hu, Zhaohui Feng (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - November 29, 2020 Category: Drugs & Pharmacology Source Type: research

Tumor microenvironment as a therapeutic target in cancer
Publication date: Available online 28 November 2020Source: Pharmacology & TherapeuticsAuthor(s): Yi Xiao, Dihua Yu (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - November 29, 2020 Category: Drugs & Pharmacology Source Type: research

Targeted treatment of alcoholic liver disease based on inflammatory signalling pathways
Publication date: Available online 27 November 2020Source: Pharmacology & TherapeuticsAuthor(s): Bingjian Wen, Chengcheng Zhang, Jingwen Zhou, Zhengyan Zhang, Qishi Che, Hua Cao, Yan Bai, Jiao Guo, Zhengquan Su (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - November 28, 2020 Category: Drugs & Pharmacology Source Type: research

Sirtuins' control of autophagy and mitophagy in cancer
Publication date: Available online 24 November 2020Source: Pharmacology & TherapeuticsAuthor(s): Michele Aventaggiato, Enza Vernucci, Federica Barreca, Matteo A. Russo, Marco Tafani (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - November 25, 2020 Category: Drugs & Pharmacology Source Type: research

Assay design and development strategies for finding Hsp90 inhibitors and their role in human diseases
Publication date: Available online 24 November 2020Source: Pharmacology & TherapeuticsAuthor(s): Monimoy Banerjee, Ishita Hatial, Bradley M. Keegan, Brian S.J. Blagg (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - November 24, 2020 Category: Drugs & Pharmacology Source Type: research